{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:43:40Z","timestamp":1760060620493,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T00:00:00Z","timestamp":1757203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Rudolf Geigy Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Understanding Plasmodium falciparum population genetic diversity is crucial to assess the impact of malaria control interventions. This study investigated P. falciparum genetic diversity using merozoite surface protein 1 (msp1), msp2 and glutamate-rich protein (glurp) in Korhogo district, Northern C\u00f4te d\u2019Ivoire. DNA was extracted from dried blood spots (DBSs) collected in the health district of Korhogo between 2019 and 2020. The msp1, msp2, and glurp genes were amplified by polymerase chain reaction (PCR), and amplicon sizes were determined by capillary electrophoresis. Out of 179 samples randomly selected and genotyped, 82% were successfully amplified for msp1, 85% for msp2, and 75% for glurp. For msp1, the K1 allelic family had 20 genotypes, MAD20 had 23, and RO33 had only one genotype. For msp2, there were 59 and 33 genotypes for 3D7 and FC27, respectively, and for glurp, 45 genotypes were detected. The parasite population was highly diverse with an expected heterozygosity (HE) of \u22650.9 for all 3 markers. Our study showed high genetic diversity of msp1, msp2, and glurp in P. falciparum isolates from Korhogo district, Northern C\u00f4te d\u2019Ivoire. These data could provide baseline information on P. falciparum genetic diversity for further epidemiological studies, needed to assess interventions implemented in this area.<\/jats:p>","DOI":"10.3390\/tropicalmed10090255","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T08:06:32Z","timestamp":1757318792000},"page":"255","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genetic Diversity of Plasmodium falciparum in Korhogo Health District, Northern C\u00f4te d\u2019Ivoire"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9729-3548","authenticated-orcid":false,"given":"Edjronk\u00e9 M. A.","family":"Beni\u00e9","sequence":"first","affiliation":[{"name":"Laboratoire de Biologie et Cytologie Animale, Unit\u00e9 de Formation et de Recherche Sciences de la Nature, Universit\u00e9 Nangui Abrogoua, Abidjan 02 BP 801, C\u00f4te d\u2019Ivoire"},{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te d\u2019Ivoire, Abidjan 01 BP 1303, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Beuret","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland"},{"name":"University of Basel, Petersplatz 1, 4001 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annina","family":"Schnoz","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland"},{"name":"University of Basel, Petersplatz 1, 4001 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6386-9872","authenticated-orcid":false,"given":"Sara L.","family":"Cantoreggi","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland"},{"name":"University of Basel, Petersplatz 1, 4001 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8409-3678","authenticated-orcid":false,"given":"Xavier C.","family":"Ding","sequence":"additional","affiliation":[{"name":"FIND, Campus Biotech, 9 Ch. des Mines, 1202 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1003-9294","authenticated-orcid":false,"given":"Kigbafori D.","family":"Silu\u00e9","sequence":"additional","affiliation":[{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te d\u2019Ivoire, Abidjan 01 BP 1303, C\u00f4te d\u2019Ivoire"},{"name":"Laboratoire de Biologie et Sant\u00e9, Unit\u00e9 de Formation et de Recherche Biosciences, Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, Abidjan 01 BP V34, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6944-3892","authenticated-orcid":false,"given":"Christian","family":"Nsanzabana","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland"},{"name":"University of Basel, Petersplatz 1, 4001 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,7]]},"reference":[{"key":"ref_1","unstructured":"WHO (2024, September 05). 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