{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:32:32Z","timestamp":1785407552394,"version":"3.56.0"},"reference-count":33,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1184406"],"award-info":[{"award-number":["GNT1184406"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2008697"],"award-info":[{"award-number":["2008697"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"award":["GNT1184406"],"award-info":[{"award-number":["GNT1184406"]}],"id":[{"id":"https:\/\/ror.org\/011kf5r70","id-type":"ROR","asserted-by":"publisher"}]},{"award":["2008697"],"award-info":[{"award-number":["2008697"]}],"id":[{"id":"https:\/\/ror.org\/011kf5r70","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015539","name":"Australian Government","doi-asserted-by":"publisher","award":["Research Training Program Domestic Scholarship"],"award-info":[{"award-number":["Research Training Program Domestic Scholarship"]}],"id":[{"id":"10.13039\/100015539","id-type":"DOI","asserted-by":"publisher"}]},{"award":["Research Training Program Domestic Scholarship"],"award-info":[{"award-number":["Research Training Program Domestic Scholarship"]}],"id":[{"id":"https:\/\/ror.org\/0314h5y94","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Opisthorchis viverrini (OV) is a liver fluke endemic to the Lower Mekong Basin. Infections often begin in childhood and are causally linked to cholangiocarcinoma, an often-fatal bile duct cancer. Anthelmintic treatment is the primary control strategy, but infection can recur. Therefore, additional strategies are needed. This study assessed the impact of \u201cThe Magic Glasses Opisthorchiasis\u201d (MGO), a cartoon-based intervention, on schoolchildren\u2019s OV-related knowledge, attitudes and practices (KAP). A cluster (school)-randomised controlled trial was conducted in Cambodia, Laos and Thailand. Clusters were randomised into either school health education only or with MGO. OV KAP was measured using a standardised questionnaire. FGDs and interviews were also conducted in intervention schools with schoolchildren, parents, and teachers. Cambodia intervention knowledge and attitude scores improved by 19.2 (p &lt; 0.001) and 25.3 (p &lt; 0.001) percentage points, respectively, relative to the control. Laos intervention knowledge and attitude scores improved by 19.0 (p &lt; 0.001) and 14.2 (p &lt; 0.001) percentage points. However, Thailand\u2019s intervention knowledge and attitude scores declined by 23.3 (p &lt; 0.001) and 15.8 percentage points (p &lt; 0.001). There were no improvements in behaviour scores in any country, but parents and schoolchildren in Cambodia and Laos reported improved fish preparation practices, suggesting positive spillover effects from MGO. The findings support MGO as an effective tool for school-based health education.<\/jats:p>","DOI":"10.3390\/tropicalmed11070174","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T01:03:56Z","timestamp":1782349436000},"page":"174","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of \u201cThe Magic Glasses Opisthorchiasis\u201d on Schoolchildren\u2019s Knowledge, Attitudes and Practices Surrounding Opisthorchis viverrini in the Lower Mekong Basin, a Cluster-Randomised Controlled Trial"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7657-839X","authenticated-orcid":false,"given":"Suji Y.","family":"O\u2019Connor","sequence":"first","affiliation":[{"name":"National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia"},{"name":"School of Clinical Medicine, University of New South Wales, Sydney, NSW 2033, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Lorraine","family":"Mationg","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia"},{"name":"Population Health Program, QIMR Berghofer, Brisbane, QLD 4006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7963-2139","authenticated-orcid":false,"given":"Matthew J.","family":"Kelly","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4822-5263","authenticated-orcid":false,"given":"Gail M.","family":"Williams","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Queensland, Brisbane, QLD 4006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archie C. A.","family":"Clements","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Queen\u2019s University Belfast, Belfast BT7 1NN, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8899-5919","authenticated-orcid":false,"given":"Banchob","family":"Sripa","sequence":"additional","affiliation":[{"name":"Department of Tropical Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"},{"name":"Tropical Disease Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8219-9567","authenticated-orcid":false,"given":"Somphou","family":"Sayasone","sequence":"additional","affiliation":[{"name":"Lao Tropical and Public Health Institute, Ministry of Health, Vientiane 01000, Laos"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1725-3843","authenticated-orcid":false,"given":"Virak","family":"Khieu","sequence":"additional","affiliation":[{"name":"National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh 12101, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinley","family":"Wangdi","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia"},{"name":"HEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Canberra, ACT 2617, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7588-7273","authenticated-orcid":false,"given":"Donald E.","family":"Stewart","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Griffith University, Gold Coast, QLD 4215, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5662-8636","authenticated-orcid":false,"given":"Sirikachorn","family":"Tangkawattana","sequence":"additional","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"},{"name":"Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apiporn T.","family":"Suwannatrai","sequence":"additional","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"},{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanthanom","family":"Savathdy","sequence":"additional","affiliation":[{"name":"Lao Tropical and Public Health Institute, Ministry of Health, Vientiane 01000, Laos"},{"name":"Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland"},{"name":"University of Basel, 4001 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3269-4193","authenticated-orcid":false,"given":"Visal","family":"Khieu","sequence":"additional","affiliation":[{"name":"National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh 12101, Cambodia"},{"name":"Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland"},{"name":"University of Basel, 4001 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Odermatt","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland"},{"name":"University of Basel, 4001 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine A.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Population Health Program, QIMR Berghofer, Brisbane, QLD 4006, Australia"},{"name":"School of Medicine, University of Queensland, Brisbane, QLD 4072, Australia"},{"name":"School of Biological Sciences, Queensland University of Technology, Brisbane, QLD 4001, Australia"},{"name":"Centre for Tropical Health and Emerging Diseases, QIMR Berghofer, Brisbane, QLD 4006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangduan","family":"Wannachart","sequence":"additional","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald P.","family":"McManus","sequence":"additional","affiliation":[{"name":"Population Health Program, QIMR Berghofer, Brisbane, QLD 4006, 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