{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T03:36:35Z","timestamp":1778038595376,"version":"3.51.4"},"reference-count":41,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2018,2,19]],"date-time":"2018-02-19T00:00:00Z","timestamp":1518998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Melioidosis continues to be a major health care problem in Brunei Darussalam. The age of patients, gender distribution, risk factors, and clinical presentations are similar to those reported from other countries in the region. The incidence of melioidosis was high during the wet months and in the Temburong district, which has the highest annual rainfall. In spite of adequate facilities for diagnosis and treatment, the mortality remains high (27%). Women and those presenting with septic shock had higher mortality. There is a case for making melioidosis a notifiable disease in Brunei Darussalam. Coordinated efforts between policy-makers and various stakeholders are required to effectively combat the disease.<\/jats:p>","DOI":"10.3390\/tropicalmed3010020","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T03:54:22Z","timestamp":1519098862000},"page":"20","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Melioidosis in Brunei Darussalam"],"prefix":"10.3390","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1096-6231","authenticated-orcid":false,"given":"Ketan","family":"Pande","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BG 1710, Negara Brunei Darussalam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khairul Azmi","family":"Abd Kadir","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BG 1710, Negara Brunei Darussalam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosmonaliza","family":"Asli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BG 1710, Negara Brunei Darussalam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vui Heng","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Medicine, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BG 1710, Negara Brunei Darussalam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Limmathurotsakul, D., Golding, N., Dance, D.A.B., Messina, J.P., Pigott, D.M., Moyes, C.L., Rolim, D.B., Bertherat, E., Day, N.P.J., and Peacock, S.J. 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