{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:25:42Z","timestamp":1790717142161,"version":"4.1.0"},"reference-count":33,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2018,11,3]],"date-time":"2018-11-03T00:00:00Z","timestamp":1541203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Based on an ensemble of global circulation models (GCMs), four representative concentration pathways (RCPs) and several ongoing and planned Coupled Model Intercomparison Projects (CMIPs), the Intergovernmental Panel on Climate Change (IPCC) predicts that global, average temperatures will increase by at least 1.5 \u00b0C in the near future and more by the end of the century if greenhouse gases (GHGs) emissions are not genuinely tempered. While the RCPs are indicative of various amounts of GHGs in the atmosphere the CMIPs are designed to improve the workings of the GCMs. We chose RCP4.5 which represented a medium GHG emission increase and CMIP5, the most recently completed CMIP phase. Combining this meteorological model with a biological counterpart model accounted for replication and survival of the snail intermediate host as well as maturation of the parasite stage inside the snail at different ambient temperatures. The potential geographical distribution of the three main schistosome species: Schistosoma japonicum, S. mansoni and S. haematobium was investigated with reference to their different transmission capabilities at the monthly mean temperature, the maximum temperature of the warmest month(s) and the minimum temperature of the coldest month(s). The set of six maps representing the predicted situations in 2021\u20132050 and 2071\u20132100 for each species mainly showed increased transmission areas for all three species but they also left room for potential shrinkages in certain areas.<\/jats:p>","DOI":"10.3390\/tropicalmed3040117","type":"journal-article","created":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T10:43:45Z","timestamp":1541414625000},"page":"117","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Potential Impact of Climate Change on Schistosomiasis: A Global Assessment Attempt"],"prefix":"10.3390","volume":"3","author":[{"given":"Guo-Jing","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4002 Basel, Switzerland"},{"name":"University of Basel, CH-4002 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Bergquist","sequence":"additional","affiliation":[{"name":"Ingerod, SE-454 94 Brastad, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,3]]},"reference":[{"key":"ref_1","unstructured":"(2018, October 15). WHO. Available online: http:\/\/www.who.int\/neglected_diseases\/NTD_RoadMap_2012_Fullversion.pdf."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S1473-3099(06)70521-7","article-title":"Schistosomiasis and water resources development: Systematic review, meta-analysis, and estimates of people at risk","volume":"6","author":"Steinmann","year":"2006","journal-title":"Lancet Infect. Dis."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Hotez, P., Alvarado, M., Bas\u00e1\u00f1ez, M., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S., Brown, A., Buckle, G., and Budke, C. (2014). (DALYs and HALE Collaborators). The gobal burden of disease study 2010: Interpretation and implications for the neglected tropical diseases. PLoS Negl. Trop. Dis., 8.","DOI":"10.1371\/journal.pntd.0002865"},{"key":"ref_4","unstructured":"WHO (2018, August 20). Schistosomiasis Fact Sheet of 20 February 2018. Available online: http:\/\/www.who.int\/news-room\/fact-sheets\/detail\/schistosomiasis."},{"key":"ref_5","unstructured":"WHO (World Health Organization) (2002). Prevention and Control of Schistosomiasis and Soil-Transmitted Helminthiasis: Report of a WHO Expert Committee, World Health Organization."},{"key":"ref_6","first-page":"495","article-title":"The global burden of disease in 1990: Summary results, sensitivity analysis and future directions","volume":"723","author":"Murray","year":"1994","journal-title":"Bull. World Health Organ."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/S0140-6736(12)61689-4","article-title":"Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990\u20132010: A systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Murray","year":"2012","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/S0140-6736(17)32130-X","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990\u20132016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"39010100","author":"Hay","year":"2017","journal-title":"Lancet"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.actatropica.2013.12.001","article-title":"Health metrics for helminth infections","volume":"141","author":"King","year":"2015","journal-title":"Acta Trop."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"King, C.H. (2015). It\u2019s Time to Dispel the Myth of \u201cAsymptomatic\u201d Schistosomiasis. PLoS Negl. Trop. Dis., 92.","DOI":"10.1371\/journal.pntd.0003504"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(18)30098-9","article-title":"Underestimation of the global burden of schistosomiasis","volume":"39110118","author":"King","year":"2018","journal-title":"Lancet"},{"key":"ref_12","unstructured":"Jamieson, B.G.M. (2016). Diagnostic tests for schistosomiasis. Schistosoma: Biology, Pathology and Control, CRC Press."},{"key":"ref_13","unstructured":"IPCC (2018, September 05). Principles Governing IPCC Work, Approved 1\u20133 October 1998, Last Amended 14\u201318 October 2013. Available online: https:\/\/ipcc.ch\/pdf\/ipcc-principles\/ipcc-principles.pdf."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1161-0301(00)00058-7","article-title":"Bases and limits to using \u2018degree.day\u2019 units","volume":"13","author":"Bonhomme","year":"2000","journal-title":"Eur. J. Agron."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1439-0418.1993.tb01222.x","article-title":"Experimental assessment of a degree-day model for predicting the development of parasites in the field","volume":"116","author":"Bernal","year":"1993","journal-title":"J. Appl. Entiron."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1007\/s00436-006-0315-8","article-title":"Effect of temperature on the development of Schistosoma japonicum within Oncomelania hupensis, and hibernation of O. hupensis","volume":"100","author":"Yang","year":"2007","journal-title":"Parasitol. Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"188","DOI":"10.4269\/ajtmh.2008.78.188","article-title":"Potential Impact of Climate Change on Schistosomiasis Transmission in China","volume":"78","author":"Zhou","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_18","first-page":"127","article-title":"Electrophoretic detection of genetic variability among Schistosoma japonicum isolates by sequence-related amplified polymorphism","volume":"47","author":"Yang","year":"2005","journal-title":"Parasitologia"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Zhu, G., Fan, J., and Peterson, A. (2017). Schistosoma japonicum transmission risk maps at present and under climate change in mainland China. PLoS Negl. Trop. Dis., 1110.","DOI":"10.1371\/journal.pntd.0006021"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13071-014-0617-0","article-title":"Predicting the effects of climate change on Schistosoma mansoni transmission in eastern Africa","volume":"8","author":"McCreesh","year":"2015","journal-title":"Parasit. Vectors"},{"key":"ref_21","first-page":"406","article-title":"Combining process-based and correlative models improves predictions of climate change effects on Schistosoma mansoni transmission in eastern Africa","volume":"11","author":"Stensgaard","year":"2016","journal-title":"Geosp. Health"},{"key":"ref_22","unstructured":"Moss, R., Babiker, M., Brinkman, S., Calvo, E., Carter, T., Edmonds, J., Elgizouli, I., Emori, S., Erda, L., and Hibbard, K. (2008). Towards New Scenarios for Analysis of Emissions: Climate Change, Impacts and Response Strategies, Intergovernmental Panel on Climate Change."},{"key":"ref_23","unstructured":"IPPC Working Group I (2018, September 05). The Scientific Basis. Available online: https:\/\/www.ipcc.ch\/ipccreports\/tar\/wg1\/029.htm."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1002\/joc.1276","article-title":"Very high resolution interpolated climate surfaces for global land areas","volume":"25","author":"Hijmans","year":"2005","journal-title":"Int. J. Clim."},{"key":"ref_25","first-page":"159","article-title":"Experimental epidemiology of schistosomiasis. I. The prepatent period and cercarial production of Schistosoma mansoni in Biomphalaria snails at various constant temperatures","volume":"63","year":"1980","journal-title":"Parasitol. Res."},{"key":"ref_26","first-page":"513","article-title":"Prepatency of Schistosoma haematobium in snails at different constant temperatures","volume":"13","author":"Roushdy","year":"1983","journal-title":"J. Egypt. Soc. Parasitol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0001-706X(01)00103-6","article-title":"Satellite climatology and the environmental risk of Schistosoma mansoni in Ethiopia and east Africa","volume":"79","author":"Malone","year":"2001","journal-title":"Acta Trop."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s40249-018-0424-5","article-title":"Schistosomiasis in Zambia: A systematic review of past and present experiences","volume":"71","author":"Kalinda","year":"2018","journal-title":"Infect. Dis. Poverty"},{"key":"ref_29","unstructured":"Hewitt, R., and Willingham, A.L. (2018). Elimination of Schistosomiasis in the Caribbean. TropicalMed, in press."},{"key":"ref_30","first-page":"453","article-title":"Predicting the spatial distribution of Biomphalaria straminea; a potential intermediate host for Schistosoma mansoni in China","volume":"113","author":"Habib","year":"2016","journal-title":"Geosp. Health"},{"key":"ref_31","first-page":"33","article-title":"The species of the genus Bulinus: Intermediate hosts of Schistosoma","volume":"331","year":"1965","journal-title":"Bull. World Health Organ."},{"key":"ref_32","first-page":"127","article-title":"A potential impact of climate change and water resource development on the transmission of Schistosoma japonicum in China","volume":"47","author":"Yang","year":"2005","journal-title":"Parassitologia"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.3201\/eid2009.140928","article-title":"Schistosomiasishaematobium, Corsica, France","volume":"209","author":"Berry","year":"2014","journal-title":"Emerg. Infect. 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