{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T08:44:29Z","timestamp":1767084269318,"version":"build-2065373602"},"reference-count":16,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:00:00Z","timestamp":1548633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Melioidosis is rare in the United States and endemic to Southeast Asia and Australia. Treatment includes an initial intensive phase of intravenous ceftazidime or meropenem monotherapy depending on severity. The following report describes a case of persistent bacteremia with ceftazidime failure and prolonged meropenem therapy on a ceftazidime-susceptible strain of Burkholderia pseudomallei.<\/jats:p>","DOI":"10.3390\/tropicalmed4010020","type":"journal-article","created":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T03:40:55Z","timestamp":1548733255000},"page":"20","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Persistent Burkholderia pseudomallei Bacteremia in A Filipino Immigrant to the United States: A Case Report"],"prefix":"10.3390","volume":"4","author":[{"given":"Sumbul","family":"Meraj","sequence":"first","affiliation":[{"name":"HSHS St. Elizabeth\u2019s Hospital, O\u2019Fallon, IL 62269, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandy","family":"Rodenberg","sequence":"additional","affiliation":[{"name":"HSHS St. Elizabeth\u2019s Hospital, O\u2019Fallon, IL 62269, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Thannum","sequence":"additional","affiliation":[{"name":"HSHS St. Elizabeth\u2019s Hospital, O\u2019Fallon, IL 62269, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jared","family":"Sheley","sequence":"additional","affiliation":[{"name":"HSHS St. Elizabeth\u2019s Hospital, O\u2019Fallon, IL 62269, USA"},{"name":"School of Pharmacy, Southern Illinois University Edwardsville, Edwardsville, IL 62025, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jena","family":"Foreman","sequence":"additional","affiliation":[{"name":"HSHS St. Elizabeth\u2019s Hospital, O\u2019Fallon, IL 62269, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,1,28]]},"reference":[{"key":"ref_1","unstructured":"Melioidosis (2018, December 01). 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Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"17165","DOI":"10.1073\/pnas.1111020108","article-title":"Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in, B. pseudomallei","volume":"1","author":"Chantratita","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1128\/AAC.48.5.1763-1765.2004","article-title":"Outcomes of Patients with Melioidosis Treated with Meropenem","volume":"48","author":"Cheng","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ijantimicag.2014.01.005","article-title":"Treatment and prophylaxis of melioidosis","volume":"43","author":"Dance","year":"2014","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_14","unstructured":"Clinicaltrials.gov (2019, January 16). A Randomized Double Blinded Comparison of Ceftazidime and Meropenem in Severe Melioidosis (ATOM), Available online: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00579956?cond=melioidosis&rank=3."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"858","DOI":"10.4269\/ajtmh.2011.10-0618","article-title":"Repeat blood culture positive for, B. pseudomallei indicates an increased risk of death from melioidosis","volume":"84","author":"Limmathurotsakul","year":"2011","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_16","unstructured":"(2019, January 18). Lexicomp Online, Lexi-Drugs Online, Hudson, Ohio: Wolters Kluwer Clinical Drug Information, Inc.. 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