{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T17:18:39Z","timestamp":1775841519353,"version":"3.50.1"},"reference-count":33,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/22448-0"],"award-info":[{"award-number":["2019\/22448-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["19\/02679-7"],"award-info":[{"award-number":["19\/02679-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/18230-6"],"award-info":[{"award-number":["2018\/18230-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/26928-6"],"award-info":[{"award-number":["2019\/26928-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.503842\/2020-00"],"award-info":[{"award-number":["88887.503842\/2020-00"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has infected over 90 million people worldwide, therefore it is considered a pandemic. SARS-CoV-2 infection can lead to severe pneumonia, acute respiratory distress syndrome (ARDS), septic shock, and\/or organ failure. Individuals receiving a heart transplantation (HT) may be at higher risk of adverse outcomes attributable to COVID-19 due to immunosuppressives, as well as concomitant infections that may also influence the prognoses. Herein, we describe the first report of two cases of HT recipients with concomitant infections by SARS-CoV-2, Trypanosoma cruzi, and cytomegalovirus (CMV) dissemination, from the first day of hospitalization due to COVID-19 in the intensive care unit (ICU) until the death of the patients.<\/jats:p>","DOI":"10.3390\/tropicalmed6010022","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T16:12:10Z","timestamp":1613146330000},"page":"22","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["SARS-CoV-2 Infection and CMV Dissemination in Transplant Recipients as a Treatment for Chagas Cardiomyopathy: A Case Report"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5937-2402","authenticated-orcid":false,"given":"Sarah Cristina","family":"Gozzi-Silva","sequence":"first","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, 05508-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gil","family":"Benard","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3602-3306","authenticated-orcid":false,"given":"Ricardo Wesley","family":"Alberca","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0067-8933","authenticated-orcid":false,"given":"Tatiana Mina","family":"Yendo","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5622-903X","authenticated-orcid":false,"given":"Franciane Mouradian Emidio","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, 05508-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5546-1977","authenticated-orcid":false,"given":"Luana de Mendon\u00e7a","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle Rosa","family":"Beserra","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Julia","family":"Pietrobon","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, 05508-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily Araujo de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, 05508-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Cl\u00e1udia Calvielli Castelo","family":"Branco","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology and Immunodeficiencies (LIM-56), Institute of Tropical Medicine of School of Medicine of S\u00e3o Paulo (FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of 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(FMUSP), 05403-000 S\u00e3o Paulo, Brazil"},{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, 05508-000 S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical Features of Patients Infected with 2019 Novel Coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/s41577-020-0308-3","article-title":"COVID-19: Immunopathology and Its Implications for Therapy","volume":"20","author":"Cao","year":"2020","journal-title":"Nat. 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