{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:09:39Z","timestamp":1760234979283,"version":"build-2065373602"},"reference-count":44,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>(1) Background: In an area with a high prevalence of multi-drug resistant Gram-negative bacteria (MDR-GNB), we investigated the colonization of nursing home residents by such organisms. (2) Methods: A point prevalence study was performed in six nursing homes of the Heraklion area on the island of Crete. A rectal swab was taken and cultured from each participant, while additional risk factors such as recent hospitalization or antimicrobial usage were recorded and evaluated. (3) Results: A total of 137 nursing home residents were included in the study. Their mean age was 82.1 years and 19.7% were males. In total, cultures yielded 255 GNB; E. coli, K. pneumoniae and P. aeruginosa were the most common. Among the microorganisms cultured, 17.6% had the extended-spectrum beta-lactamase phenotype, while 18% were MDR. A statistically significant association was found between recent antimicrobial use and colonization by MDR-GNB; (4) Conclusions: Colonization by MDR-GNB was found to be highly prevalent in nursing home residents. Recent antimicrobial use was associated with MDR-GNB carriage.<\/jats:p>","DOI":"10.3390\/tropicalmed6030123","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T22:02:04Z","timestamp":1625522524000},"page":"123","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Rectal Colonization by Drug Resistant Bacteria in Nursing Home Residents in Crete, Greece"],"prefix":"10.3390","volume":"6","author":[{"given":"Aikaterini","family":"Moschou","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Heraklion, Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1082-5674","authenticated-orcid":false,"given":"Petros","family":"Ioannou","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Heraklion, Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni","family":"Moraitaki","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, University Hospital of Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitra","family":"Stafylaki","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, University Hospital of Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0945-1732","authenticated-orcid":false,"given":"Sofia","family":"Maraki","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, University Hospital of Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Samonis","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Heraklion, Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diamantis P.","family":"Kofteridis","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Heraklion, Heraklion, PC 71110 Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ajic.2017.01.022","article-title":"Prevalence of Multidrug-Resistant Gram-Negative Bacteria among Nursing Home Residents: A Systematic Review and Meta-Analysis","volume":"45","author":"Aliyu","year":"2017","journal-title":"Am. 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