{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:58:20Z","timestamp":1774533500277,"version":"3.50.1"},"reference-count":27,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T00:00:00Z","timestamp":1638921600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Rabies transmitted by sylvatic populations has become an increasing concern in Brazil. A total of 113 participants with a history of contact with sylvatic populations were interviewed in 27 municipalities of Cear\u00e1 State in northeast Brazil. Questionnaires included questions on knowledge, attitudes and practices (KAP) regarding sylvatic rabies. Most of the respondents (92%) knew about rabies and confirmed at least one species that transmitted the disease (79.6%). Of these respondents, 69% mentioned monkeys, and 67.2% mentioned dogs. However, 16% of the respondents listed an incorrect species. In general, knowledge on the symptoms and signs and on prevention measures was weak. The majority raised pets (93.8%), most commonly dogs and cats, and, of all the pets, 85.7% were claimed to be vaccinated against rabies. A total of 67.3% reported the appearance of free-living wild animals around their houses, mostly marmosets and wild canids; 18.3% reported that sylvatic populations had attacked animals or humans. Seventy-three percent had raised or still were raising wild animals as pets, mostly capuchin monkeys (79.5%) and marmosets (24.1%). This is the first KAP study on sylvatic rabies in Brazil. The data indicate important knowledge gaps and risk behavior within a high-risk population. There is a need for strengthening and improving sylvatic rabies surveillance and control, combined with the intensification of education and information campaigns.<\/jats:p>","DOI":"10.3390\/tropicalmed6040209","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T23:30:00Z","timestamp":1639006200000},"page":"209","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Knowledge, Attitudes and Practices Regarding Sylvatic Rabies among High-Risk Households in Cear\u00e1 State, Brazil"],"prefix":"10.3390","volume":"6","author":[{"given":"Nayl\u00ea Francelino Holanda","family":"Duarte","sequence":"first","affiliation":[{"name":"Postgraduate Program in Public Health, School of Medicine, Federal University of Cear\u00e1, Fortaleza 60430-140, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2863-0787","authenticated-orcid":false,"given":"Patr\u00edcia Pereira Lima","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Public Health, School of Medicine, Federal University of Cear\u00e1, Fortaleza 60430-140, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle Bastos","family":"Araujo","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana Regina","family":"Favoretto","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7017-9286","authenticated-orcid":false,"given":"Phyllis Catharina","family":"Romijn","sequence":"additional","affiliation":[{"name":"Agricultural Research Institute of Rio de Janeiro, Rio de Janeiro 24120-191, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael William Pontes","family":"Neres","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, Cear\u00e1 State University, Fortaleza 60714-903, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel Holanda","family":"Varela","sequence":"additional","affiliation":[{"name":"Department of Biology, Federal University of Cear\u00e1, Fortaleza 60440-900, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walber Feij\u00f3","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Brazilian Institute of Environment and Renewable Natural Resources, Wild Animal Sorting Center, Fortaleza 60843-150, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2967-532X","authenticated-orcid":false,"given":"Carlos Henrique","family":"Alencar","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Public Health, School of Medicine, Federal University of Cear\u00e1, Fortaleza 60430-140, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7845-5510","authenticated-orcid":false,"given":"Jorg","family":"Heukelbach","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Public Health, School of Medicine, Federal University of Cear\u00e1, Fortaleza 60430-140, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100155","DOI":"10.1016\/j.onehlt.2020.100155","article-title":"Review of rabies in Nepal","volume":"10","author":"Pantha","year":"2020","journal-title":"One Health"},{"key":"ref_2","unstructured":"World Health Organization (2018). Expert Consultation on Rabies: Third Report, World Health Organization."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Lacouture, M.E. (2013). Epidemiology and Burden of Disease. Dermatologic Principles and Practice in Oncology, John Wiley & Sons.","DOI":"10.1002\/9781118590638"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Hampson, K., Coudeville, L., Lembo, T., Sambo, M., Kieffer, A., Attlan, M., Barrat, J., Blanton, J.D., Briggs, D.J., and Cleaveland, S. (2015). Estimating the global burden of endemic canine rabies. PLoS Negl. Trop. Dis., 9.","DOI":"10.1371\/journal.pntd.0003786"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/zph.12670","article-title":"Increased detection of rabies virus in bats in Cear\u00e1 State (Northeast Brazil) after implementation of a passive surveillance programme","volume":"67","author":"Duarte","year":"2020","journal-title":"Zoonoses Public Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e2020354","DOI":"10.1590\/s1679-49742021000100010","article-title":"Epidemiologia da raiva humana no estado do Cear\u00e1, 1970 a 2019","volume":"30","author":"Duarte","year":"2021","journal-title":"Epidemiol. Serv. Sa\u00fade"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Da Costa, L.J.C., and Fernandes, M.E.F. (2016). Rabies: Knowledge and practices regarding rabies in rural communities of the Brazilian Amazon basin. PLoS Negl. Trop. Dis., 10.","DOI":"10.1371\/journal.pntd.0004474"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"105156","DOI":"10.1016\/j.actatropica.2019.105156","article-title":"Knowledge, attitude & practices (KAPs) regarding rabies endemicity among the community members, Pakistan","volume":"200","author":"Khan","year":"2019","journal-title":"Acta Trop."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/0970-0218.42854","article-title":"Knowledge, attitude, behavior and practice study on dog-bites and its management in the context of prevention of rabies in a rural community of Gujarat","volume":"30","author":"Singh","year":"2005","journal-title":"Indian J. Community Med."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Kabeta, T., Deresa, B., Tigre, W., Ward, M.P., and Mor, S.M. (2015). Knowledge, attitudes and practices of animal bite victims attending an Anti-rabies Health Center in Jimma Town, Ethiopia. PLoS Negl. Trop. Dis., 9.","DOI":"10.1371\/journal.pntd.0003867"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.3201\/eid1212.060429","article-title":"Rabies virus maintained by dogs in humans and terrestrial wildlife, Cear\u00e1 State, Brazil","volume":"12","author":"Favoretto","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"ref_12","first-page":"17","article-title":"Integration of human rabies surveillance and preventive measures in the State of Cear\u00e1, Northeast Brazil","volume":"1","author":"Duarte","year":"2021","journal-title":"One Health Implement. Res."},{"key":"ref_13","unstructured":"Instituto Brasileiro de Estat\u00edstica e Geografia (2017). Censo Demogr\u00e1fico 2010."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/zph.12527","article-title":"Non-human primates as a reservoir for rabies virus in Brazil","volume":"66","author":"Kotait","year":"2019","journal-title":"Zoonoses Public Health"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e01042021","DOI":"10.1590\/0037-8682-0104-2021","article-title":"Clinical aspects of human rabies in the state of Cear\u00e1, Brazil: An overview of 63 cases","volume":"54","author":"Duarte","year":"2021","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref_16","unstructured":"Minist\u00e9rio da Sa\u00fade (2021, July 04). Raiva: O Que \u00e9, Causas, Sintomas, Tratamento, Diagn\u00f3stico e Preven\u00e7\u00e3o, Available online: http:\/\/www.saude.gov.br\/saude-de-a-z\/raiva\/#epidemiologia."},{"key":"ref_17","first-page":"2","article-title":"Reservat\u00f3rios silvestres do v\u00edrus da raiva: Um desafio para a sa\u00fade p\u00fablica","volume":"4","author":"Kotait","year":"2007","journal-title":"BEPA. Bol. Epidemiol. Paul."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ntampaka, P., Nyaga, P.N., Niragire, F., Gathumbi, J.K., and Tukei, M. (2019). Knowledge, attitudes and practices regarding rabies and its control among dog owners in Kigali city, Rwanda. PLoS ONE, 20.","DOI":"10.1101\/500595"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"409","DOI":"10.20506\/rst.37.2.2811","article-title":"Rabies control in Europe: An overview of past, current and future strategies","volume":"37","author":"Freuling","year":"2018","journal-title":"Rev. Sci. Tech."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0000549","article-title":"Oral rabies vaccination in North America: Opportunities, complexities and challenges","volume":"3","author":"Slate","year":"2009","journal-title":"PLoS Negl. Trop. Dis."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1590\/S0037-86821999000500011","article-title":"Resposta imune produzida por vacinas anti-r\u00e1bicas em sag\u00fcis (Callithrix sp)","volume":"32","author":"Andrade","year":"1999","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1590\/S0037-86822011005000031","article-title":"Risco de transmiss\u00e3o do v\u00edrus da raiva oriundo de sagui (Callithrix jacchus), domiciliado e semidomiciliado, para o homem na regi\u00e3o metropolitana de Fortaleza, estado do Cear\u00e1","volume":"44","author":"Aguiar","year":"2011","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Glasgow, L., Worme, A., Keku, E., and Forde, M. (2019). Knowledge, attitudes, and practices regarding rabies in Grenada. PLoS Negl. Trop. Dis., 13.","DOI":"10.1371\/journal.pntd.0007079"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Awuni, B., Tarkang, E., Manu, E., Amu, H., Ayanore, M.A., Aku, F.Y., Ziema, S.A., Bosoka, S.A., Adjuik, M., and Kweku, M. (2019). Dog Owners\u2019 knowledge about rabies and other factors that influence canine anti-rabies vaccination in the Upper East Region of Ghana. Trop. Med. Infect. Dis., 4.","DOI":"10.3390\/tropicalmed4030115"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Bihon, A., Meresa, D., and Tesfaw, A. (2020). Rabies: Knowledge, Attitude and Practices in and Around South Gondar, North West Ethiopia. Diseases, 8.","DOI":"10.3390\/diseases8010005"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Rinchen, S., Tenzin, T., Hall, D., van der Meer, F., Sharma, B., Dukpa, K., and Cork, S.C. (2019). A community-based knowledge, attitude, and practice survey on rabies among cattle owners in selected areas of Bhutan. PLoS Negl. Trop. Dis., 13.","DOI":"10.1371\/journal.pntd.0007305"},{"key":"ref_27","first-page":"1","article-title":"One Health & Implementation Research: Improving health for all","volume":"1","author":"Heukelbach","year":"2021","journal-title":"One Health Implement. Res."}],"container-title":["Tropical Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2414-6366\/6\/4\/209\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:43:04Z","timestamp":1760168584000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2414-6366\/6\/4\/209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,8]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["tropicalmed6040209"],"URL":"https:\/\/doi.org\/10.3390\/tropicalmed6040209","relation":{},"ISSN":["2414-6366"],"issn-type":[{"value":"2414-6366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,8]]}}}