{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:54:46Z","timestamp":1789750486405,"version":"4.0.1"},"reference-count":83,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>While chronic schistosomiasis is pathologically well defined, the acute form of the disease is less well understood. It is generally agreed that early lesions, such as lung nodules and bladder polyps, are reversible, which impedes identification of the time elapsed since exposure. The intermediate stage between the acute and the chronic forms of schistosomiasis requires further investigation, as does the clinical stage due to lesions remaining after treatment. With current schistosomiasis control efforts gradually progressing to elimination, there is a need to focus on post-transmission schistosomiasis, which not only refers to remaining lesions from previous infections, but also accounts for the potential presence of surviving worms after treatment. This issue is particularly salient for migrants from endemic to non-endemic countries and should be kept in mind for returning expatriates from schistosomiasis-endemic countries. Negative stool examination or urine filtration are generally taken as indicative of cure since rectoscopy for Schistosoma mansoni infection, or cystoscopy for S. haematobium infection, are rarely performed. However, pathology of affected organs may persist indefinitely, while potentially remaining live worms could produce additional pathology. Hence, post-transmission schistosomiasis can prevail for years after elimination of the disease, and thus, warrant further attention.<\/jats:p>","DOI":"10.3390\/tropicalmed7040055","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T21:29:15Z","timestamp":1648762155000},"page":"55","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Schistosomiasis at the Crossroad to Elimination: Review of Eclipsed Research with Emphasis on the Post-Transmission Agenda"],"prefix":"10.3390","volume":"7","author":[{"given":"Michal","family":"Giboda","sequence":"first","affiliation":[{"name":"Institute of Parasitology, Czech Academy of Science, CZ 370 01 \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0190-1084","authenticated-orcid":false,"given":"Robert","family":"Bergquist","sequence":"additional","affiliation":[{"name":"Ingerod 407, 545 30 Brastad, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrg","family":"Utzinger","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, CH-4123 Allschwil, Switzerland"},{"name":"University of Basel, CH-4003 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"ref_1","first-page":"72","article-title":"Fernere Beobachtungen \u00fcber das die Pfortader des Menschen bewohnende Distomum haematobium und sein Verh\u00e4ltnis zu gewissen pathologischen Bildungen, von Dr. Th. Bilharz in Cairo (aus brieflichen Mittheilungen an Professor v. Siebold vom 29 M\u00e4rz 1852)","volume":"4","author":"Bilharz","year":"1853","journal-title":"Z. Wiss. Zool."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/bmj.1.2881.411","article-title":"On the relation between the terminal spined and lateral-spined eggs of bilharzia","volume":"1","author":"Leiper","year":"1916","journal-title":"Br. Med. J."},{"key":"ref_3","first-page":"129","article-title":"Praziquantel, a new broad-spectrum antischistosomal agent","volume":"52","author":"Andrews","year":"1979","journal-title":"Z. Parasitenkd."},{"key":"ref_4","first-page":"767","article-title":"Multicentre trials of praziquantel in human schistosomiasis: Design and techniques","volume":"57","author":"Davis","year":"1979","journal-title":"Bull. World Health Organ."},{"key":"ref_5","unstructured":"Jamieson, B.G.M. (2016). Acute schistosomiasis. Schistosoma: Biology, Pathology and Control, CRC Press."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1017\/S0031182000040889","article-title":"\u201cHost\u201d antigens associated with schistosomes: Observations on their attachment and their nature","volume":"61","author":"Clegg","year":"1970","journal-title":"Parasitology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4269\/ajtmh.2005.72.115","article-title":"Schistosoma japonicum and occult blood loss in endemic villages in Leyte, the Philippines","volume":"72","author":"Kanzaria","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"862","DOI":"10.4269\/ajtmh.2012.12-0248","article-title":"Mechanism of anemia in Schistosoma mansoni-infected school children in western Kenya","volume":"87","author":"Butler","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e1004246","DOI":"10.1371\/journal.ppat.1004246","article-title":"Schistosome feeding and regurgitation","volume":"10","author":"Skelly","year":"2014","journal-title":"PLoS Pathog."},{"key":"ref_10","unstructured":"Jamieson, B.G.M. (2016). Diagnostic tests for schistosomiasis. Schistosoma: Biology, Pathology and Control, CRC Press."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S1473-3099(07)70053-1","article-title":"Katayama syndrome","volume":"7","author":"Ross","year":"2007","journal-title":"Lancet Infect. Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1086\/341895","article-title":"Schistosomiasis and international travel","volume":"35","author":"Corachan","year":"2002","journal-title":"Clin. Infect. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.parint.2008.04.004","article-title":"Effect of floods on the transmission of schistosomiasis in the Yangtze River valley, People\u2019s Republic of China","volume":"57","author":"Wu","year":"2008","journal-title":"Parasitol. Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.tmaid.2010.11.002","article-title":"Schistosomiasis in travellers and migrants","volume":"9","author":"Clerinx","year":"2011","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/QCO.0b013e328318978f","article-title":"Praziquantel: Mechanisms of action, resistance and new derivatives for schistosomiasis","volume":"21","author":"Doenhoff","year":"2008","journal-title":"Curr. Opin. Infect. Dis."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s40249-017-0286-2","article-title":"Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?","volume":"6","author":"Bergquist","year":"2017","journal-title":"Infect. Dis. Poverty"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/S0140-6736(13)61949-2","article-title":"Human schistosomiasis","volume":"383","author":"Colley","year":"2014","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jinf.2005.07.022","article-title":"Imported Katayama fever: Clinical and biological features at presentation and during treatment","volume":"52","author":"Bottieau","year":"2006","journal-title":"J. Infect."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1469-0691.2009.03131.x","article-title":"Acute schistosomiasis, a diagnostic and therapeutic challenge","volume":"16","author":"Paris","year":"2010","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.pt.2020.05.009","article-title":"New insights on acute and chronic schistosomiasis: Do we need a redefinition?","volume":"36","author":"Gobbi","year":"2020","journal-title":"Trends Parasitol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.7861\/clinmedicine.15-1-67","article-title":"Schistosomiasis in non-endemic countries","volume":"15","author":"Coltart","year":"2015","journal-title":"Clin. Med."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Roure, S., Valerio, L., P\u00e9rez-Qu\u00edlez, O., Fern\u00e1ndez-Rivas, G., Mart\u00ednez-Cuevas, O., Alc\u00e1ntara-Rom\u00e1n, A., Viasus, D., Pedro-Botet, M.L., Sabri\u00e0, M., and Clotet, B. (2017). Epidemiological, clinical, diagnostic and economic features of an immigrant population of chronic schistosomiasis sufferers with long-term residence in a non-endemic country (North Metropolitan area of Barcelona, 2002\u20132016). PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0185245"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s40249-018-0440-5","article-title":"Shistosomiasis in immigrants, refugees and travellers in an Italian referral centre for tropical diseases","volume":"7","author":"Marchese","year":"2018","journal-title":"Infect. Dis. Poverty"},{"key":"ref_24","first-page":"373","article-title":"Migration of the people and parasites: Facts from survey of 5511 foreigners","volume":"157","author":"Giboda","year":"2018","journal-title":"Cas. Lek. Cesk."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e18481","DOI":"10.1097\/MD.0000000000018481","article-title":"Chronic schistosomiasis in African immigrants in Israel: Lessons for the non-endemic setting","volume":"98","author":"Paran","year":"2019","journal-title":"Medicine"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"101508","DOI":"10.1016\/j.tmaid.2019.101508","article-title":"Severe complications of imported schistosomiasis, Spain: A retrospective observational study","volume":"35","year":"2020","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0035-9203(84)90129-9","article-title":"A review of schistosomiasis in immigrants in Western Australia, demonstrating the unusual longevity of Schistosoma mansoni","volume":"78","author":"Harris","year":"1984","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"144","DOI":"10.7205\/MILMED.172.2.144","article-title":"Latent schistosomiasis in Portuguese soldiers","volume":"172","author":"Vieira","year":"2007","journal-title":"Mil. Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0169-4758(99)01487-8","article-title":"Post-transmission schistosomiasis","volume":"15","author":"Giboda","year":"1999","journal-title":"Parasitol. Today"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0001-706X(00)00120-0","article-title":"Post-transmission schistosomiasis: A new agenda","volume":"77","author":"Giboda","year":"2000","journal-title":"Acta Trop."},{"key":"ref_31","first-page":"159","article-title":"Field studies of a rapid, accurate means of quantifying Schistosoma haematobium eggs in urine samples","volume":"54","author":"Peters","year":"1976","journal-title":"Bull. World Health Organ."},{"key":"ref_32","first-page":"397","article-title":"A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni","volume":"14","author":"Katz","year":"1972","journal-title":"Rev. Inst. Med. Trop. S\u00e3o Paulo"},{"key":"ref_33","unstructured":"WHO (1991). Bench Aids for the Diagnosis of Intestinal Parasites, World Health Organization. [2nd ed.]. Available online: https:\/\/apps.who.int\/iris\/handle\/10665\/324883."},{"key":"ref_34","first-page":"346","article-title":"Efficacy of praziquantel treatment of schistosomiasis in a non-endemic country: A follow-up of parasitological, clinical and immunological parameters","volume":"36","author":"Giboda","year":"1992","journal-title":"J. Hyg. Epidemiol. Microbiol. Immunol."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"B\u00e4renbold, O., Raso, G., Coulibaly, J.T., N\u2019Goran, E.K., Utzinger, J., and Vounatsou, P. (2017). Estimating sensitivity of the Kato-Katz technique for the diagnosis of Schistosoma mansoni and hookworm in relation to infection intensity. PLoS Negl. Trop. Dis., 11.","DOI":"10.1371\/journal.pntd.0005953"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2307\/2530597","article-title":"Size and shape analysis of schistomsome egg-counts in Egyptian autopsy data","volume":"34","author":"Mosimann","year":"1978","journal-title":"Biometrics"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Danso-Appiah, A., Utzinger, J., Liu, J., and Olliaro, P. (2008). Drugs for treating urinary schistosomiasis. Cochrane Database Syst. Rev., CD000053.","DOI":"10.1002\/14651858.CD000053.pub2"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Danso-Appiah, A., Olliaro, P.L., Donegan, S., Sinclair, D., and Utzinger, J. (2013). Drugs for treating Schistosoma mansoni infection. Cochrane Database Syst. Rev., CD000528.","DOI":"10.1002\/14651858.CD000528.pub2"},{"key":"ref_39","first-page":"130","article-title":"Ultrasonographic assessment of urinary tract lesions due to Schistosoma haematobium after consecutive years of treatment with praziquantel","volume":"21","author":"Laurent","year":"1990","journal-title":"Trop. Med. Parasitol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/BF01002772","article-title":"Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections","volume":"11","author":"Junqueira","year":"1979","journal-title":"Histochem. J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0014-4894(65)90037-8","article-title":"In vitro cultivation of Schistosoma mansoni","volume":"16","author":"Clegg","year":"1965","journal-title":"Exp. Parasitol."},{"key":"ref_42","first-page":"98","article-title":"Schistosoma mansoni eggs as a target for praziquantel: Efficacy of oral application in mice","volume":"97","author":"Giboda","year":"1994","journal-title":"J. Trop. Med. Hyg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"990","DOI":"10.3181\/00379727-130-33706","article-title":"Schistosoma mansoni eggs: An electron microscopic study of shell pores and microbarbs","volume":"130","author":"Race","year":"1969","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4269\/ajtmh.1988.39.52","article-title":"The ultrastructure of the Schistosoma mansoni egg","volume":"39","author":"Neill","year":"1988","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_45","first-page":"63","article-title":"The ultrastructure of Schistosoma mansoni egg: The line of hatching","volume":"29","author":"Giboda","year":"1992","journal-title":"Helminthologia"},{"key":"ref_46","first-page":"55","article-title":"Alkaline phosphatase as marker of Schistosoma mansoni egg viability","volume":"41","author":"Giboda","year":"1994","journal-title":"Folia Parasitol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0022-2011(80)90040-3","article-title":"The fine structure of the miracidium of Schistosoma mansoni","volume":"36","author":"Pan","year":"1980","journal-title":"J. Invertebr. Path."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/0014-4894(90)90104-K","article-title":"The hatching of schistosome eggs","volume":"70","author":"Xu","year":"1990","journal-title":"Exp. Parasitol."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Gu, K., Li, Y.-S., Driguez, P., Zeng, Q.-G., Yu, X.-L., Sun, H., Cai, L., He, Y.-K., Wang, W.S.-Y., and McManus, D.P. (2017). Clinical diagnostic value of viable Schistosoma japonicum eggs detected in host tissues. BMC Infect. Dis., 17.","DOI":"10.1186\/s12879-017-2362-4"},{"key":"ref_50","unstructured":"WHO (2022, March 12). Factsheet Schistosomiasis. Dated 8 January 2022. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/schistosomiasis."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41572-018-0013-8","article-title":"Schistosomiasis","volume":"4","author":"McManus","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1056\/NEJMoa1812165","article-title":"Schistosomiasis\u2014assessing progress toward the 2020 and 2025 global goals","volume":"381","author":"Deol","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Khieu, V., Sayasone, S., Muth, S., Kirinoki, M., Laymanivong, S., Ohmae, H., Huy, R., Chanthapaseuth, T., Yajima, A., and Phetsouvanh, R. (2019). Elimination of schistosomiasis mekongi from endemic areas in Cambodia and the Lao People\u2019s Democratic Republic: Current status and plans. Trop. Med. Infect. Dis., 4.","DOI":"10.3390\/tropicalmed4010030"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.actatropica.2012.04.013","article-title":"Time to set the agenda for schistosomiasis elimination","volume":"128","author":"Rollinson","year":"2013","journal-title":"Acta Trop."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S1473-3099(21)00090-6","article-title":"Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: A spatiotemporal modelling study","volume":"22","author":"Kokaliaris","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4269\/ajtmh.1982.31.92","article-title":"Schistosomiasis control in the People\u2019s Republic of China","volume":"31","author":"Mao","year":"1982","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.actatropica.2005.08.004","article-title":"Conquering schistosomiasis in China: The long march","volume":"96","author":"Utzinger","year":"2005","journal-title":"Acta Trop."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Chen, J., Xu, J., Bergquist, R., Li, S.-Z., and Zhou, X.-N. (2018). \u201cFarewell to the God of Plague\u201d: The importance of political commitment towards the elimination of schistosomiasis. Trop. Med. Infect. Dis., 3.","DOI":"10.3390\/tropicalmed3040108"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Wang, W., Bergquist, R., King, C.H., and Yang, K. (2021). Elimination of schistosomiasis in China: Current status and future prospects. PLoS Negl. Trop. Dis., 15.","DOI":"10.1371\/journal.pntd.0009578"},{"key":"ref_60","first-page":"3","article-title":"The war against a regional disease in Japan: A history of the eradication of schistosomiasis japonica","volume":"39","author":"Kajihara","year":"2011","journal-title":"Trop. Med. Health"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1017\/S0031182016000883","article-title":"Elimination of urogenital schistosomiasis in Iran: Past history and the current situation","volume":"143","author":"Khademvatan","year":"2016","journal-title":"Parasitology"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"3868970","DOI":"10.1155\/2020\/3868970","article-title":"Review of the urinary schistosomiasis control in Morocco (1960\u20132018)","volume":"2020","author":"Balahbib","year":"2020","journal-title":"Interdiscip. Perspect. Infect. Dis."},{"key":"ref_63","first-page":"186","article-title":"Global distribution of schistosomiasis. CEGET\/WHO Atlas","volume":"37","author":"Doumenge","year":"1984","journal-title":"World Health Stat. Q."},{"key":"ref_64","first-page":"125","article-title":"The incidence and distribution of Schistosoma mansoni and other and absence of helminths in Puerto Rico","volume":"21","author":"Weller","year":"1945","journal-title":"P. R. J. Public Health Trop. Med."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4269\/ajtmh.1977.26.109","article-title":"Morbidity from Schistosoma mansoni in a Puerto Rican community: A population-based study","volume":"26","author":"Cline","year":"1977","journal-title":"Am. J. Trop. Hyg."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"564","DOI":"10.4269\/ajtmh.1997.57.564","article-title":"Human schistosomiasis in Puerto Rico: Reduced prevalence rate and absence of Biomphalaria gabrata","volume":"57","author":"Giboda","year":"1997","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"671","DOI":"10.4269\/ajtmh.1998.58.671","article-title":"A case of ectopic schistosomiasis in Puerto Rico with some observations on the biology of the parasite","volume":"58","author":"File","year":"1998","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Hewitt, R., and Willingham, A.L. (2019). Status of schistosomiasis elimination in the Caribbean region. Trop. Med. Infect. Dis., 4.","DOI":"10.3390\/tropicalmed4010024"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0140-6736(02)09781-7","article-title":"Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: A longitudinal study","volume":"360","author":"Karanja","year":"2002","journal-title":"Lancet"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0001-706X(00)00126-1","article-title":"Laparoscopic diagnosis and clinical course of chronic schistosomiasis japonica","volume":"77","author":"Hayashi","year":"2000","journal-title":"Acta Trop."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1443-1661.2010.00935.x","article-title":"Schistosomiasis japonica identified by laparoscopic and colonoscopic examination","volume":"22","author":"Hosho","year":"2010","journal-title":"Dig. Endosc."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/dc.20725","article-title":"Diagnosis of schistosomiasis japonica infection coincident with hepatocellular carcinoma by fine-needle aspiration","volume":"35","author":"Chen","year":"2007","journal-title":"Diagn. Cytopathol."},{"key":"ref_73","first-page":"1001","article-title":"The circumoval precipitin test in Schistosoma mansoni. A study of 300 patients","volume":"182","author":"Gonzalez","year":"1962","journal-title":"JAMA"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1001\/jama.1953.13.1081","article-title":"Studies in human subjects on active immunization against poliomyelitis. 1. A preliminary report","volume":"151","author":"Salk","year":"1953","journal-title":"J. Am. Med. Assoc."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/j.1749-6632.1955.tb42551.x","article-title":"Characteristics and genetic potentialities of experimentally produced and naturally occurring variants of poliomyelitis virus","volume":"61","author":"Sabin","year":"1955","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"5458","DOI":"10.1128\/JCM.42.12.5458-5461.2004","article-title":"Diagnosis of schistosomiasis by reagent strip test for detection of circulating cathodic antigen","volume":"42","author":"Wichers","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0001-706X(00)00115-7","article-title":"Immunodiagnosis of schistosomiasis by determination of the circulating antigens CAA and CCA, in particular in individuals with recent or light infections","volume":"77","author":"Polderman","year":"2000","journal-title":"Acta Trop."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.actatropica.2014.08.004","article-title":"An ultra-sensitive assay targeting the circulating anodic antigen for the diagnosis of Schistosoma japonicum in a low-endemic area, People\u2019s Republic of China","volume":"141","author":"Xu","year":"2015","journal-title":"Acta Trop."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.4269\/ajtmh.2012.12-0177","article-title":"Field evaluation of a PCR test for Schistosoma japonicum egg detection in low-prevalence regions of China","volume":"87","author":"Fung","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4269\/ajtmh.12-0639","article-title":"A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of schistosomiasis mansoni","volume":"88","author":"Colley","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"409","DOI":"10.4269\/ajtmh.12-0741","article-title":"Good things are worth waiting for","volume":"88","author":"Bergquist","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Masong, M.C., Wepnje, G.B., Marlene, N.T., Gamba, V., Mengue, M.-T., Kouokam, E., Stothard, J.R., and Ekobo, A.L.S. (2021). Female genital schistosomiasis (FGS) in Cameroon: A formative epidemiological and socioeconomic investigation in eleven rural fishing communities. PLoS Glob. Public Health, 1.","DOI":"10.1371\/journal.pgph.0000007"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1016\/S0140-6736(13)60317-7","article-title":"Neurological presentation of schistosomiasis","volume":"381","author":"Szekeres","year":"2013","journal-title":"Lancet"}],"container-title":["Tropical Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2414-6366\/7\/4\/55\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:47:38Z","timestamp":1760136458000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2414-6366\/7\/4\/55"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":83,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4]]}},"alternative-id":["tropicalmed7040055"],"URL":"https:\/\/doi.org\/10.3390\/tropicalmed7040055","relation":{},"ISSN":["2414-6366"],"issn-type":[{"value":"2414-6366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,31]]}}}