{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:18:12Z","timestamp":1760231892893,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"],"award-info":[{"award-number":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"],"award-info":[{"award-number":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Tutor System","award":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"],"award-info":[{"award-number":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"]}]},{"name":"Schistosomiasis Japonica, Endemic Disease, and Parasitic Disease Foundation of Jiangsu Province","award":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"],"award-info":[{"award-number":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"]}]},{"name":"Suzhou \u201cScience and Education Revitalize Health\u201d Youth Science and Technology Project","award":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"],"award-info":[{"award-number":["2021YFC2300800","2021YFC2300803","32161143036","82072309","Qngg2021031","x202106","KJXW2021057"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>A new formulation (suspension concentrate, SC) of PBQ [1-(4-chlorophenyl)-3-(pyridin-3-yl) urea] was used in water network schistosomiasis-endemic areas to test its molluscicidal efficacy and the acute toxicity to crustaceans. PBQ (20% SC), 26% metaldehyde, and niclosamide suspension concentrate [MNSC (26% SC)] were used both in ditch and field experiments for the molluscicidal efficacy comparison. Acute toxicity tests of two molluscicides were conducted using Neocaridina denticulate and Eriocheir sinensis. Both in the field and ditch experiments, PBQ exhibited comparable molluscicidal efficacy with MNSC. At doses of 0.50 g\/m3 and 0.50 g\/m2, the snail mortalities were more than 90% three days after PBQ (20% SC) application. Compared with previous tests, PBQ (20% SC) exhibited higher molluscicidal activity than PBQ (25% wettable powder, 25% WP) used in Jiangling and showed similar mollucicidal activity to PBQ (25% WP) used in Dali and Poyang Lake. The 96 h LC50 value of MNSC against Eriocheir sinensis was 283.84 mg a.i.\/L. At the concentration of PBQ (20% SC) 1000 mg a.i.\/L, all Eriocheir sinensis were alive. The 96 h LC50 values of PBQ and MNSC against Neocaridina denticulate were 17.67 and 14.05 mg a.i.\/L, respectively. In conclusion, PBQ (20% SC) had a comparable molluscicidal efficacy with MNSC (26% SC) and PBQ (25% WP). Furthermore, it showed lower toxicity to the crustacean species, better solubility, no floating dust, and convenience for carriage. PBQ (20% SC) was suitable for controlling snails in the water network schistosomiasis-endemic areas.<\/jats:p>","DOI":"10.3390\/tropicalmed7100294","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T06:13:27Z","timestamp":1665468807000},"page":"294","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Biosafety Evaluation for Crustaceans: A Novel Molluscicide PBQ Using against Oncomelania hupensis, the Intermediate Host of Schistosoma japonica"],"prefix":"10.3390","volume":"7","author":[{"given":"Qianwen","family":"Shi","sequence":"first","affiliation":[{"name":"Suzhou Center for Disease Prevention and Control, Suzhou 215004, China"},{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Duan","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqiang","family":"Qin","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weisi","family":"Wang","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Shen","sequence":"additional","affiliation":[{"name":"Wuzhong District Center for Disease Control and Prevention, Suzhou 215100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuetao","family":"Hua","sequence":"additional","affiliation":[{"name":"Wuzhong District Center for Disease Control and Prevention, Suzhou 215100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling\u2019e","family":"Shen","sequence":"additional","affiliation":[{"name":"Suzhou Center for Disease Prevention and Control, Suzhou 215004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqian","family":"Cao","sequence":"additional","affiliation":[{"name":"Wuzhong District Center for Disease Control and Prevention, Suzhou 215100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fukang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Wuzhong District Center for Disease Control and Prevention, Suzhou 215100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingzhi","family":"Wu","sequence":"additional","affiliation":[{"name":"Suzhou Center for Disease Prevention and Control, Suzhou 215004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3172-5218","authenticated-orcid":false,"given":"Shizhu","family":"Li","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40249-018-0414-7","article-title":"Snail-borne parasitic diseases: An update on global epidemiological distribution, transmission interruption and control methods","volume":"7","author":"Lu","year":"2018","journal-title":"Infect. 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