{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T01:13:52Z","timestamp":1775351632096,"version":"3.50.1"},"reference-count":59,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"State University of Santa Cruz (UESC)","award":["001"],"award-info":[{"award-number":["001"]}]},{"DOI":"10.13039\/501100002322","name":"Bahia State Research Support Foundation (FAPESB)","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis.<\/jats:p>","DOI":"10.3390\/tropicalmed8030142","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T02:04:11Z","timestamp":1677463451000},"page":"142","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Treatment of Animal Tungiasis: What\u2019s New?"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8940-2548","authenticated-orcid":false,"given":"Katharine Costa","family":"dos Santos","sequence":"first","affiliation":[{"name":"Departamento de Ci\u00eancias Agr\u00e1rias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Ilh\u00e9us 45662-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2961-8069","authenticated-orcid":false,"given":"Paula Elisa","family":"Brand\u00e3o Guedes","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Agr\u00e1rias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Ilh\u00e9us 45662-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamille Bispo de Carvalho","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Agr\u00e1rias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Ilh\u00e9us 45662-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiani Vitor","family":"Harvey","sequence":"additional","affiliation":[{"name":"Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7879-1824","authenticated-orcid":false,"given":"Renata Santiago Alberto","family":"Carlos","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Agr\u00e1rias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Ilh\u00e9us 45662-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2915.2009.00807.x","article-title":"Sand flea (Tunga spp.) infections in man and domestic animals: State of the art","volume":"23","author":"Panmpiglione","year":"2009","journal-title":"Med. 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