{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T14:04:13Z","timestamp":1781186653160,"version":"3.54.1"},"reference-count":36,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad de Antioquia and Universidad Cooperativa de Colombia","award":["INV3161"],"award-info":[{"award-number":["INV3161"]}]},{"name":"Universidad Cooperativa de Colombia","award":["INV3161"],"award-info":[{"award-number":["INV3161"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>This study compared the clinical\u2013parasitological profiles of gestational (GM), placental (PM), and congenital (CM) malaria in northwestern Colombia. A cross-sectional study with 829 pregnant women, 549 placentas, and 547 newborns was conducted. The frequency of GM was 35.8%, PM 20.9%, and CM 8.5%. P. vivax predominated in GM; in PM, the proportion of P. vivax and P. falciparum was similar; in CM, P. falciparum predominated. The main clinical findings were headache (49%), anemia (32%), fever (24%), and musculoskeletal pain (13%). The clinical manifestations were statistically higher in P. vivax infections. In submicroscopic GM (positive with qPCR and negative with thick blood smear), the frequency of anemia, sore throat, and a headache was statistically higher compared with pregnant women without malaria. GM, PM, and CM reduce birth weight and head circumference. In Colombia, this is the first research on the clinical characteristics of GM, PM, and CM; contrary to evidence from other countries, P. vivax and submicroscopic infections are associated with clinical outcomes.<\/jats:p>","DOI":"10.3390\/tropicalmed8060292","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T02:00:19Z","timestamp":1685066419000},"page":"292","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical and Parasitological Profiles of Gestational, Placental and Congenital Malaria in Northwestern Colombia"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7101-929X","authenticated-orcid":false,"given":"Jaiberth Antonio","family":"Cardona-Arias","sequence":"first","affiliation":[{"name":"School of Microbiology, Universidad de Antioquia (UdeA), Medell\u00edn 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1361-3124","authenticated-orcid":false,"given":"Luis Felipe","family":"Higuita-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"School of Microbiology, Universidad de Antioquia (UdeA), Medell\u00edn 050010, Colombia"},{"name":"School of Medicine, Universidad Cooperativa de Colombia, Medell\u00edn 050012, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0428-9887","authenticated-orcid":false,"given":"Jaime","family":"Carmona-Fonseca","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n Salud y Comunidad C\u00e9sar Uribe Piedrah\u00edta, Universidad de Antioquia, Medell\u00edn 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2023, January 15). 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