{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T14:31:17Z","timestamp":1793457077643,"version":"4.5.0"},"reference-count":35,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Global Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Tuberculosis Preventive Treatment (TPT) is a powerful tool for preventing the TB infection from developing into active TB disease, and has recently been expanded to all household contacts of TB cases in India. This study employs a mixed-methods approach to conduct a situational analysis of the initial phase of TPT implementation among household contacts of pulmonary TB patients in three districts of Delhi, India. It was completed using a checklist based assessments, care cascade data, and qualitative analysis. Our observations indicated that organizational structure and planning were established, but implementation of TPT was suboptimal with issues in drug availability and procurement, budget, human resources, and training. Awareness and motivation, and shorter regimen, telephonic assessment, and collaboration with NGOs emerged as enablers. Apprehension about taking TPT, erratic drug supply, long duration of treatment, side effects, overburden, large population, INH resistance, data entry issues, and private provider reluctance emerged as barriers. The study revealed potential solutions for optimizing TPT implementation. It is evident that, while progress has been made in TPT implementation, there is room for improvement and refinement across various domains.<\/jats:p>","DOI":"10.3390\/tropicalmed9010024","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T10:39:47Z","timestamp":1705487987000},"page":"24","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Situation Analysis of Early Implementation of Programmatic Management of Tuberculosis Preventive Treatment among Household Contacts of Pulmonary TB Patients in Delhi, India"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8601-4440","authenticated-orcid":false,"given":"Yasir","family":"Alvi","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi 110062, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1531-9519","authenticated-orcid":false,"given":"Sairu","family":"Philip","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Government Medical College, Kottayam 686008, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanu","family":"Anand","sequence":"additional","affiliation":[{"name":"Scientist E, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, New Delhi 110029, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8320-1016","authenticated-orcid":false,"given":"Palanivel","family":"Chinnakali","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzana","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi 110062, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1340-3146","authenticated-orcid":false,"given":"Neeta","family":"Singla","sequence":"additional","affiliation":[{"name":"Department of Training, National Institute of TB & Respiratory Disease, New Delhi 110030, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5257-5074","authenticated-orcid":false,"given":"Pruthu","family":"Thekkur","sequence":"additional","affiliation":[{"name":"Centre for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwani","family":"Khanna","sequence":"additional","affiliation":[{"name":"Delhi State NTEP, New Delhi 110002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BK","family":"Vashishat","sequence":"additional","affiliation":[{"name":"State TB Cell, Gulabi Bagh, New Delhi 110007, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"ref_1","unstructured":"WHO (2022). 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