{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:52:24Z","timestamp":1792806744116,"version":"4.5.0"},"reference-count":90,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Background: Toxoplasmosis has been of public health concern due to direct associations with socioeconomic vulnerability and inadequate living conditions. Methods: Accordingly, the present study aimed to assess antibodies against T. gondii, historical reported toxoplasmosis cases and associated socio-environmental risk factors in Pinhais, a full urban area of Curitiba, currently the eighth biggest metropolitan area of Brazil. Anti-Toxoplasma gondii antibodies were assessed by an indirect immunofluorescence reaction (RIFI). Owner and dog samples were also tested by IFAT to anti-Leishmania spp. and anti-Trypanosoma cruzi antibodies. Results: Overall, 20\/135 (14.8%) persons and 13\/133 (9.8%) dogs from 25 different households were considered seropositive to T. gondii. All samples were seronegative to Leishmania spp. and Trypanosoma cruzi. Conclusions: Although no significant covariates were found in the regression model, statistically associated risk factors in the bivariate analysis included no public water use (p = 0.016) and drinking raw milk (p = 0.041) for owners, and obesity (p = 0.028) and tick infestation (p = 0.03) for dogs. In addition, a spatial cluster of T. gondii seropositivity for both owners and their dogs overlapped the location of historic reported cases of human acquired, gestational and congenital toxoplasmosis. Finally, the results herein showed tick infestation as an indicator of socio-environmental risk for T. gondii exposure in the household environment, and dogs may be used as sentinels for human toxoplasmosis cases.<\/jats:p>","DOI":"10.3390\/tropicalmed9070143","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T05:22:38Z","timestamp":1719552158000},"page":"143","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["One Health Approach to Toxoplasmosis: Owner and Dog Seropositivity as Spatial Indicators of Risk Areas for Acquired, Gestational and Congenital Transmission"],"prefix":"10.3390","volume":"9","author":[{"given":"Natacha","family":"Sohn-Hausner","sequence":"first","affiliation":[{"name":"Graduate College of Cell and Molecular Biology, Federal University of Paran\u00e1, Curitiba 80035-050, PR, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2512-1525","authenticated-orcid":false,"given":"Ricardo Guedes","family":"Correa","sequence":"additional","affiliation":[{"name":"Graduate College of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba 80035-050, PR, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6579-1278","authenticated-orcid":false,"given":"Louise Bach","family":"Kmetiuk","sequence":"additional","affiliation":[{"name":"Graduate College of Cell and Molecular Biology, Federal University of Paran\u00e1, Curitiba 80035-050, PR, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn Cristine","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Veterinary Hygiene and Public Health, Sao Paulo State University, Botucatu 18618-681, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Nunes","family":"de Moraes","sequence":"additional","affiliation":[{"name":"Department of Veterinary Hygiene and Public Health, Sao Paulo State University, Botucatu 18618-681, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle dos Santos","family":"Rocha","sequence":"additional","affiliation":[{"name":"Department of Veterinary Hygiene and Public Health, Sao Paulo State University, Botucatu 18618-681, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5127-0762","authenticated-orcid":false,"given":"Helio","family":"Langoni","sequence":"additional","affiliation":[{"name":"Department of Veterinary Hygiene and Public Health, Sao Paulo State University, Botucatu 18618-681, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4182-5821","authenticated-orcid":false,"given":"Alexander Welker","family":"Biondo","sequence":"additional","affiliation":[{"name":"Graduate College of Cell and Molecular Biology, Federal University of Paran\u00e1, Curitiba 80035-050, PR, Brazil"},{"name":"Graduate College of Veterinary Medicine, Federal University of Paran\u00e1, Curitiba 80035-050, PR, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"ref_1","first-page":"256","article-title":"Construction and evaluation of the Toxoplasma gondii DNA vaccine targeting DEC-205","volume":"42","author":"Chen","year":"2022","journal-title":"Pak. Vet. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"4126","DOI":"10.1016\/j.ygeno.2021.10.019","article-title":"Development of CRISPR-CAS9 based RNA drugs against Eimeria tenella infection","volume":"113","author":"Mohsin","year":"2021","journal-title":"Genomics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40249-020-0630-9","article-title":"Neglected tropical diseases: An effective global response to local poverty-related disease priorities","volume":"9","author":"Engels","year":"2020","journal-title":"Infect. Dis. Poverty"},{"key":"ref_4","unstructured":"(2024, May 15). CDC Parasites, Available online: https:\/\/www.cdc.gov\/parasites\/index.html."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.rvsc.2020.10.019","article-title":"Foodborne transmission of Toxoplasma gondii infection in the last decade. An overview","volume":"135","author":"Almeria","year":"2021","journal-title":"Res. Vet. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1128\/microbiolspec.PFS-0011-2015","article-title":"Toxoplasma gondii as a Parasite in Food: Analysis and Control","volume":"4","author":"Hill","year":"2016","journal-title":"Microbiol. Spectr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0304-4017(97)00048-4","article-title":"Mechanical transmission of Toxoplasma gondii oocysts by dogs","volume":"73","author":"Lindsay","year":"1997","journal-title":"Vet. Parasitol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/j.1749-6632.1996.tb53546.x","article-title":"An Apparent Role of Dogs in the Transmission of Toxoplasma gondii: The Probable Importance of Xenosmophilia","volume":"791","author":"FRENKEL","year":"1996","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"189","DOI":"10.5433\/1679-0359.2008v29n1p189","article-title":"Toxoplasmose canina: Aspectos cl\u00ednicos e patol\u00f3gicos","volume":"29","author":"Bresciani","year":"2008","journal-title":"Semin. Ci\u00eancias Agr\u00e1rias"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.bjid.2013.11.009","article-title":"Congenital toxoplasmosis in a reference center of Paran\u00e1, Southern Brazil","volume":"18","author":"Capobiango","year":"2014","journal-title":"Braz. J. Infect. Dis."},{"key":"ref_11","unstructured":"(2024, May 15). Zoonosis y Enfermedades Transmisibles Comunes al Hombre y a los Animales: Parasitosis, v.3, 3 ed. Available online: https:\/\/iris.paho.org\/handle\/10665.2\/3323?show=full&locale-attribute=pt."},{"key":"ref_12","first-page":"803","article-title":"Neglected parasitic infections: What every family physician needs to know","volume":"89","author":"Woodhall","year":"2014","journal-title":"Am. Fam. Physician"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1017\/S0031182012000765","article-title":"Toxoplasmosis in humans and animals in Brazil: High prevalence, high burden of disease, and epidemiology","volume":"139","author":"Dubey","year":"2012","journal-title":"Parasitology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"326","DOI":"10.3201\/eid1202.041115","article-title":"Waterborne toxoplasmosis, Brazil, from field to gene","volume":"12","author":"Wada","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1590\/S1413-81232011000700071","article-title":"Aspectos sociopol\u00edticos da epidemia de toxoplasmose em Santa Isabel do iva\u00ed (PR)","volume":"16","author":"Freire","year":"2011","journal-title":"Cienc. Saude Coletiva"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"s74","DOI":"10.1017\/S1049023X19001602","article-title":"Outbreak of Toxoplasmosis in the City of Santa Maria, Brazil","volume":"34","author":"Burguez","year":"2019","journal-title":"Prehosp. Disaster Med."},{"key":"ref_17","unstructured":"Dubey, J.P. (2023). Toxoplasmosis of Animals and Humans, CRC Press."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1080\/14787210.2019.1682550","article-title":"Tick transmission of toxoplasmosis","volume":"17","year":"2019","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"ref_19","first-page":"333","article-title":"Preliminary study on the occurrence of Toxoplasma gondii in Ixodes ricinus ticks from north-western Poland with the use of PCR","volume":"15","author":"Sroka","year":"2008","journal-title":"Ann. Agric. Environ. Med."},{"key":"ref_20","first-page":"185","article-title":"The role of ticks in transmission cycle of Toxoplasma gondii","volume":"62","author":"Skotarczak","year":"2016","journal-title":"Ann. Parasitol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40249-016-0106-0","article-title":"Epidemiology of toxoplasmosis: Role of the tick Haemaphysalis longicornis","volume":"5","author":"Zhou","year":"2016","journal-title":"Infect. Dis. Poverty"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1127\/0941-2948\/2013\/0507","article-title":"K\u00f6ppen\u2019s climate classification map for Brazil","volume":"22","author":"Alvares","year":"2013","journal-title":"Meteorol. Z."},{"key":"ref_23","unstructured":"Pinhais, P.-P.M. (2024, May 15). de Plano de Habita\u00e7\u00e3o e Regulariza\u00e7\u00e3o Fundi\u00e1ria: Diagn\u00f3stico Final, 2010. Available online: https:\/\/silo.tips\/queue\/prefeito-municipal-luis-goularte-alves?&queue_id=-1&v=1713631289&u=MjgwNDozODk6YzAzMjoxZWRiOmFjMDI6NjgwYzphMzk0OjdiZg==."},{"key":"ref_24","first-page":"112","article-title":"Introdu\u00e7\u00e3o \u00e0s t\u00e9cnicas de imunofluoresc\u00eancia","volume":"10","author":"Camargo","year":"1974","journal-title":"Rev. Bras. Patol. Cl\u00ednica"},{"key":"ref_25","first-page":"227","article-title":"Fluorescent antibody test for the serodiagnosis of American trypanosomiasis. Technical modification employing preserved culture forms of Trypanosoma cruzi in a slide test","volume":"8","author":"Camargo","year":"1966","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"ref_26","unstructured":"(2024, June 18). Minist\u00e9rio da Sa\u00fade, Available online: https:\/\/bvsms.saude.gov.br\/bvs\/saudelegis\/gm\/2014\/prt1271_06_06_2014.html."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00436-009-1716-2","article-title":"Serological prevalence of Toxoplasma gondii antibodies in pregnant women from Southern Brazil","volume":"106","author":"Vaz","year":"2010","journal-title":"Parasitol. Res."},{"key":"ref_28","first-page":"504","article-title":"Serosurvey for Leishmania spp., Toxoplasma gondii, Trypanosoma cruzi and Neospora caninum in neighborhood dogs in Curitiba-Paran\u00e1, Brazil","volume":"25","author":"Constantino","year":"2016","journal-title":"Rev. Bras. Parasitol. Vet. = Braz. J. Vet. Parasitol. Orgao Col. Bras. Parasitol. Vet."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1590\/S1984-29612010000100012","article-title":"Surveillance of canine visceral leishmaniasis in a disease-free area","volume":"19","author":"Frehse","year":"2010","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"ref_30","first-page":"63","article-title":"Soroepidemiologia da toxoplasmose em gestantes a partir da implanta\u00e7\u00e3o do Programa de Vigil\u00e2ncia da Toxoplasmose Adquirida e Cong\u00eanita em munic\u00edpios da regi\u00e3o oeste do Paran\u00e1","volume":"34","author":"Bittencourt","year":"2012","journal-title":"Rev. Bras. Ginecol. Obs."},{"key":"ref_31","first-page":"e42102","article-title":"Seroepidemiology of toxoplasmosis in humans and dogs from a small municipality in parana, Brazil","volume":"18","author":"Benitez","year":"2017","journal-title":"Ci\u00eancia Anim. Bras."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.ijpara.2009.04.003","article-title":"Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis","volume":"39","author":"Pappas","year":"2009","journal-title":"Int. J. Parasitol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"101814","DOI":"10.1016\/j.jogoh.2020.101814","article-title":"Toxoplasmosis screening during pregnancy in France: Opinion of an expert panel for the CNGOF","volume":"49","author":"Picone","year":"2020","journal-title":"J. Gynecol. Obstet. Hum. Reprod."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1017\/S0950268813002756","article-title":"Incidence and prevalence of Toxoplasma gondii infection in women in France, 1980\u20132020: Model-based estimation","volume":"142","author":"Nogareda","year":"2014","journal-title":"Epidemiol. Infect."},{"key":"ref_35","unstructured":"Minist\u00e9rio da Sa\u00fade (BR) (2024, May 15). Protocolo de Notifica\u00e7\u00e3o e Investiga\u00e7\u00e3o: Toxoplasmose Gestacional e Cong\u00eanita, Available online: https:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/protocolo_notificacao_investigacao_toxoplasmose_gestacional_congenita.pdf."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1590\/s1984-29612019043","article-title":"Epidemiological relevance of dogs for the prevention of Toxoplasma gondii, Neospora caninum and Leptospira spp.","volume":"28","author":"Pasquali","year":"2019","journal-title":"Rev. Bras. Parasitol. Veterin\u00e1ria"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Freitas, A.R., Delai, R.R., Kmetiuk, L.B., da Silva, E.C., Martini, R., Brand\u00e3o, A.P.D., Giuffrida, R., de Barros-Filho, I.R., Costa da Silva, R., and Langoni, H. (2022). Seropositivity of Anti-Toxoplasma gondii Antibodies in Owners and Their Dogs Living on Island and Mainland Seashore Areas of Southern Brazil. Trop. Med. Infect. Dis., 7.","DOI":"10.3390\/tropicalmed7100252"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e00049","DOI":"10.1016\/j.fawpar.2019.e00049","article-title":"Environmental transmission of Toxoplasma gondii: Oocysts in water, soil and food","volume":"15","author":"Shapiro","year":"2019","journal-title":"Food Waterborne Parasitol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"729","DOI":"10.34119\/bjhrv3n1-057","article-title":"Soropreval\u00eancia e fatores de risco para toxoplasmose em gestantes na regi\u00e3o metropolitana de Goi\u00e2nia, Goi\u00e1s, Brasil","volume":"3","author":"Silveira","year":"2020","journal-title":"Braz. J. Health Rev."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1678-9199-19-23","article-title":"Toxoplasmosis, leptospirosis and brucellosis in stray dogs housed at the shelter in Umuarama municipality, Parana, Brazil","volume":"19","author":"Goncalves","year":"2013","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"253","DOI":"10.5433\/1679-0359.2015v36n1p253","article-title":"Zoonosis in dogs and cats attended by the Birth Control Project: Toxoplasma gondii, Leishmania spp. and Leptospira spp., serodiagnosis and epidemiology","volume":"36","author":"Caldart","year":"2015","journal-title":"Semin. Agrar."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"da Cunha, G.R., Pellizzaro, M., Martins, C.M., Rocha, S.M., Yamakawa, A.C., da Silva, E.C., dos Santos, A.P., Morikawa, V.M., Langoni, H., and Biondo, A.W. (2020). Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0233305"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/S0020-7519(00)00124-7","article-title":"Toxoplasma gondii: From animals to humans","volume":"30","author":"Tenter","year":"2000","journal-title":"Int. J. Parasitol."},{"key":"ref_44","first-page":"115","article-title":"Ocurrence of anti-Toxoplasma gondii antibodies and the risk factors associated with canine infection at ilh\u00e9us-itabuna region in the state of Bahia","volume":"32","author":"Carlos","year":"2010","journal-title":"Rev. Bras. Med. Vet."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1590\/S0103-84782013001100020","article-title":"Ocorr\u00eancia e fatores de risco associados \u00e0s infec\u00e7\u00f5es por Toxoplasma gondii e Neospora caninum em c \u00e3es no munic\u00edpio de Natal, Estado do Rio Grande do Norte, Nordeste do Brasil","volume":"43","author":"Dantas","year":"2013","journal-title":"Cienc. Rural"},{"key":"ref_46","first-page":"1","article-title":"Occurrence of Toxoplasma gondii antibodies in sera from dogs of the urban and rural areas from Brazil","volume":"12","author":"Gennari","year":"2003","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Machado, F.P., Kmetiuk, L.B., Teider-Junior, P.I., Pellizzaro, M., Yamakawa, A.C., Martins, C.M., Bach, R.V.W., Morikawa, V.M., de Barros-Filho, I.R., and Langoni, H. (2019). Seroprevalence of anti-Toxoplasma gondii antibodies in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0223474"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"109223","DOI":"10.1016\/j.vetpar.2020.109223","article-title":"Toxoplasma gondii infections in dogs: 2009\u20132020","volume":"287","author":"Dubey","year":"2020","journal-title":"Vet. Parasitol."},{"key":"ref_49","first-page":"9","article-title":"Serological detection of Toxoplasma gondii in domestic dogs in the western region of Cuba","volume":"9","author":"Navarrete","year":"2017","journal-title":"Vet. Parasitol. Reg. Stud. Rep."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Gebremedhin, E.Z., Sarba, E.J., Tola, G.K., Endalew, S.S., Marami, L.M., Melkamsew, A.T., Lo Presti, V.D.M., and Vitale, M. (2021). Prevalence and risk factors of Toxoplasma gondii and Leishmania spp. infections in apparently healthy dogs in west Shewa zone, Oromia, Ethiopia. BMC Vet. Res., 17.","DOI":"10.1186\/s12917-021-02992-w"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/1756-3305-5-118","article-title":"Seroprevalence of Toxoplasma gondii infection in pet dogs in Kunming, Southwest China","volume":"5","author":"Duan","year":"2012","journal-title":"Parasit. Vectors"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1590\/S1678-91992006000100012","article-title":"Serological profile of anti-Toxoplasma gondii antibodies in apparently healthy dogs of the city of Botucatu, S\u00e3o Paulo State, Brazil","volume":"12","author":"Langoni","year":"2006","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.35172\/rvz.2022.v29.704","article-title":"Atualiza\u00e7\u00f5es e padr\u00f5es da toxoplasmose humana e animal: Revis\u00e3o de literatura","volume":"29","author":"Manzini","year":"2022","journal-title":"Vet. Zootec."},{"key":"ref_54","unstructured":"Havlik, O. (1951). Experiment\u00e1ln\u012d prenos toxoplasmosy kl\u012d\u015bt\u0115tem Ornithodorus moubata. Casop\u00eds L\u00e9kar\u016f \u010cesk\u00fdch, 90, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/14905455\/."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2307\/3273853","article-title":"Experimental results on possible arthropod transmission of toxoplasmosis","volume":"39","author":"Woke","year":"1953","journal-title":"J. Parasitol."},{"key":"ref_56","unstructured":"Tanaka, T., Maeda, H., Galay, R.L., Boldbattar, D., Umemiya-Shirafuji, R., Suzuki, H., Xuan, X., Tsuji, N., and Fujisaki, K. (2012). Tick longicin implicated in the arthropod transmission of Toxoplasma gondii. J. Vet. Sci. Technol., 3."},{"key":"ref_57","first-page":"121","article-title":"Ixodes ricinus as a potential vector of Toxoplasma gondii","volume":"10","author":"Sroka","year":"2003","journal-title":"Ann. Agric. Environ. Med."},{"key":"ref_58","first-page":"613","article-title":"Isolement de Toxoplasma gondii chez des ixodid\u00e9s du genre Amblyomma naturellement infect\u00e9s","volume":"109","author":"Gidel","year":"1965","journal-title":"Ann. l\u201dInstitut. Pasteur."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3347\/kjp.2020.58.3.327","article-title":"Molecular Detection of Toxoplasma gondii in Haemaphysalis Ticks in Korea","volume":"58","author":"Kim","year":"2020","journal-title":"Korean J. Parasitol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"e009819","DOI":"10.1590\/s1984-29612019083","article-title":"Autochthonous canine visceral leishmaniasis cases occur in Paran\u00e1 state since 2012: Isolation and identification of Leishmania infantum","volume":"29","author":"Dias","year":"2020","journal-title":"Rev. Bras. Parasitol. Veterin\u00e1ria"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"347","DOI":"10.46551\/rc24482692202214","article-title":"Distribui\u00e7\u00e3o espacial dos casos de leishmaniose visceral humana e canina na \u00e1rea urbana do munic\u00edpio de Virgem da Lapa, Minas Gerais, Brasil","volume":"20","author":"Pacheco","year":"2022","journal-title":"Rev. Cerrados"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"5846","DOI":"10.36489\/saudecoletiva.2021v11i65p5846-5857","article-title":"Aspectos epidemiol\u00f3gicos e distribui\u00e7\u00e3o espacial da leishmaniose visceral em Picos, Piau\u00ed-, Brasil","volume":"11","year":"2021","journal-title":"Sa\u00fade Coletiva (Barueri)"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e2019422","DOI":"10.1590\/s1679-49742020000500002","article-title":"Visceral Leishmaniasis: Temporal and spatial distribution in Fortaleza, Cear\u00e1 State, Brazil, 2007\u20132017","volume":"29","author":"Almeida","year":"2020","journal-title":"Epidemiol. Serv. Saude"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1590\/S0103-84782010005000102","article-title":"Prevalence and epidemiology of visceral leishmaniasis in dogs and humans in the city Cuiaba, Mato Grosso, Brazil","volume":"40","author":"Almeida","year":"2010","journal-title":"Cienc. Rural"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"167","DOI":"10.14393\/Hygeia1024027","article-title":"An\u00e1lise espacial da Leishmaniose Visceral Americana no munic\u00edpio de Petrolina, Pernambuco, Brasil","volume":"10","author":"Maia","year":"2014","journal-title":"Hygeia-Rev. Bras. Geogr. M\u00e9dica Sa\u00fade"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.1590\/s1678-9946201961068","article-title":"Spatial analysis of leishmaniasis in Brazil: A systematized review","volume":"61","author":"Caldart","year":"2019","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Melo, H.A., Rossoni, D.F., and Teodoro, U. (2017). Spatial distribution of cutaneous leishmaniasis in the state of Paran\u00e1, Brazil. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0185401"},{"key":"ref_68","first-page":"32","article-title":"Diagnostic methods of canine visceral leishmaniasis","volume":"11","author":"Feitosa","year":"2006","journal-title":"Cl\u00ednica Veterin\u00e1ria"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00436-010-1890-2","article-title":"Occurrence of antibodies anti-Neospora caninum, anti-Toxoplasma gondii, and anti-Leishmania chagasi in serum of dogs from Par\u00e1 State, Amazon, Brazil","volume":"107","author":"Valadas","year":"2010","journal-title":"Parasitol. Res."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1590\/S1984-29612013005000024","article-title":"Canine visceral leishmaniasis and Chagas disease among dogs in Aragua\u00edna, Tocantins","volume":"22","author":"Morais","year":"2013","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.vetpar.2009.06.027","article-title":"Leishmania spp. and\/or Trypanosoma cruzi diagnosis in dogs from endemic and nonendemic areas for canine visceral leishmaniasis","volume":"164","author":"Troncarelli","year":"2009","journal-title":"Vet. Parasitol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijpara.2020.01.001","article-title":"Vaccination against canine leishmaniasis in Brazil","volume":"50","author":"Nogueira","year":"2020","journal-title":"Int. J. Parasitol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"e03565","DOI":"10.1590\/s1980-220x2018058603565","article-title":"Spatial distribution of Chagas disease and its correlation with health services","volume":"54","author":"Cardoso","year":"2020","journal-title":"Rev. Esc. Enferm. USP"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1590\/1980-5497201700040015","article-title":"An\u00e1lise espa\u00e7o-temporal da doen\u00e7a de chagas e seus fatores de risco ambientais e demogr\u00e1ficos no munic\u00edpio de Barcarena, Par\u00e1, Brasil","volume":"20","author":"Miranda","year":"2017","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Ferro, E., Silva, A.M., Sobral-Souza, T., Vancine, M.H., Muylaert, R.L., de Abreu, A.P., Pelloso, S.M., de Barros Carvalho, M.D., de Andrade, L., and Ribeiro, M.C. (2018). Spatial prediction of risk areas for vector transmission of Trypanosoma cruzi in the State of Paran\u00e1, southern Brazil. PLoS Negl. Trop. Dis., 12.","DOI":"10.1371\/journal.pntd.0006907"},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Mareze, M., Benitez, A.D.N., Brand\u00e3o, A.P.D., Pinto-Ferreira, F., Miura, A.C., Martins, F.D.C., Caldart, E.T., Biondo, A.W., Freire, R.L., and Mitsuka-Bregan\u00f3, R. (2019). Socioeconomic vulnerability associated to Toxoplasma gondii exposure in southern Brazil. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0212375"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3201\/eid0901.020160","article-title":"Highly endemic, waterborne toxoplasmosis in North Rio de Janeiro State, Brazil","volume":"9","author":"Jones","year":"2003","journal-title":"Emerg. Infect. Dis."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"504","DOI":"10.4269\/ajtmh.2008.78.504","article-title":"Prevalence of infection with Toxoplasma gondii among pregnant women in Cali, Colombia, South America","volume":"78","author":"Rosso","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1645\/GE-1829.1","article-title":"Seroepidemiology of Toxoplasma gondii infection in pregnant women in rural Durango, Mexico","volume":"95","author":"Liesenfeld","year":"2009","journal-title":"J. Parasitol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"528","DOI":"10.4269\/ajtmh.2010.10-0082","article-title":"Prevalence and risk factors of toxoplasmosis among pregnant women in Fortaleza, Northeastern Brazil","volume":"83","author":"Sroka","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.bjid.2012.12.003","article-title":"Gestational toxoplasmosis in Paran\u00e1 State, Brazil: Prevalence of IgG antibodies and associated risk factors","volume":"17","author":"Bittencourt","year":"2013","journal-title":"Braz. J. Infect. Dis."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"e000820","DOI":"10.1590\/s1984-29612020025","article-title":"Cumulative incidence and spatial distribution of dogs exposed to Toxoplasma gondii","volume":"29","author":"Olbera","year":"2020","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1051\/parasite\/2021049","article-title":"Toxoplasma gondii in domiciled dogs and cats in urban areas of Brazil: Risk factors and spatial distribution","volume":"28","author":"Arruda","year":"2021","journal-title":"Parasite"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.marpolbul.2012.01.040","article-title":"Climate and coastal habitat change: A recipe for a dirtier ocean","volume":"64","author":"Shapiro","year":"2012","journal-title":"Mar. Pollut. Bull."},{"key":"ref_85","unstructured":"Liberg, O., Sandell, M., Pontier, D., and Natoli, E. (2000). Density spatial organisation and reproductive tactics in the domestic cat and other felids. Incollection, 119\u2013148. Available online: https:\/\/hal.science\/hal-00427051\/document."},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Heim, R.R. (2015). An overview of weather and climate extremes\u2014Products and trends. Weather Clim. Extrem., 10.","DOI":"10.1016\/j.wace.2015.11.001"},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Semenza, J.C., and Suk, J.E. (2018). Vector-borne diseases and climate change: A European perspective. FEMS Microbiol. Lett., 365.","DOI":"10.1093\/femsle\/fnx244"},{"key":"ref_88","unstructured":"World Health Organization (2017). Global Vector Control Response 2017\u20132030, WHO."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"106432","DOI":"10.1016\/j.actatropica.2022.106432","article-title":"Toxoplasmosis in Human and Animals Around the World. Diagnosis and Perspectives in the One Health Approach","volume":"231","author":"Torrecilhas","year":"2022","journal-title":"Acta Trop."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.pt.2021.05.003","article-title":"The impact of COVID-19 on neglected parasitic diseases: What to expect?","volume":"37","author":"Miguel","year":"2021","journal-title":"Trends Parasitol."}],"container-title":["Tropical Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2414-6366\/9\/7\/143\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:06:47Z","timestamp":1760108807000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2414-6366\/9\/7\/143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":90,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["tropicalmed9070143"],"URL":"https:\/\/doi.org\/10.3390\/tropicalmed9070143","relation":{},"ISSN":["2414-6366"],"issn-type":[{"value":"2414-6366","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,28]]}}}