{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:42:27Z","timestamp":1793727747596,"version":"4.6.1"},"reference-count":45,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"German Center for Infection Research (DZIF)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Chromobacterium violaceum is a Gram-negative, facultative anaerobe proteobacterium. Its natural habitat is water and soil in tropical and subtropical regions. Human infections are characterized by rapid dissemination that can lead to high fatality rates. Here, we describe the first case of a C. violaceum infection reported from Germany. A German national with permanent residence in French Guyana contracted a C. violaceum infection presumably while bathing in a barrier lake in Brazil. The patient presented with a high fever and a crusty, erythematous skin lesion at an emergency department in Hamburg, Germany. Ultrasound and a CT scan of the abdomen revealed multiple liver abscesses. C. violaceum was detected in blood and from aspirates of the liver abscesses, using traditional culture methods and modern molecular assays. Prolonged treatment with meropenem and ciprofloxacin led to full recovery. Rapid pathogen detection and treatment initiation are of high importance in C. violaceum infections as mortality rates are overall declining but have still tended to reach up to 25% in recent years in systemic infections. Due to its broad natural drug resistance, antibiotic treatment is challenging. Increased travel activities may lead to more frequent presentation of patients with environmental pathogens of the tropics such as C. violaceum.<\/jats:p>","DOI":"10.3390\/tropicalmed9100242","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T05:50:05Z","timestamp":1729230605000},"page":"242","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Severe Systemic Chromobacterium violaceum Infection: A Case Study of a German Long-Term Resident in French Guyana"],"prefix":"10.3390","volume":"9","author":[{"given":"Caroline","family":"Klenk","sequence":"first","affiliation":[{"name":"I. Medical Department, Division of Tropical Medicine, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"},{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Schnieders","sequence":"additional","affiliation":[{"name":"I. Medical Department, Division of Tropical Medicine, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melina","family":"Heinemann","sequence":"additional","affiliation":[{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany"},{"name":"I. Medical Department, Division of Infectious Diseases, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Wiegard","sequence":"additional","affiliation":[{"name":"I. Medical Department, Ultrasound Unit, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5086-4961","authenticated-orcid":false,"given":"Henning","family":"B\u00fcttner","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9259-1885","authenticated-orcid":false,"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[{"name":"I. Medical Department, Division of Tropical Medicine, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"},{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany"},{"name":"German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel, Inhoffenstr. 7, 38124 Braunschweig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Jordan","sequence":"additional","affiliation":[{"name":"I. Medical Department, Division of Tropical Medicine, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"},{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany"},{"name":"I. Medical Department, Division of Infectious Diseases, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Sophia","family":"Mackroth","sequence":"additional","affiliation":[{"name":"Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany"},{"name":"I. Medical Department, Division of Infectious Diseases, University Medical Centre Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany"},{"name":"German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel, Inhoffenstr. 7, 38124 Braunschweig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"ref_1","first-page":"181946","article-title":"Chromobacterium violaceum Isolated from a Wound Sepsis: A Case Study from Nepal","volume":"2015","author":"Ansari","year":"2015","journal-title":"Case Rep. Infect. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"740","DOI":"10.12659\/AJCR.894509","article-title":"Chromobacterium violaceum Sepsis: Rethinking Conventional Therapy to Improve Outcome","volume":"16","author":"Richard","year":"2015","journal-title":"Am. J. 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