{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:33:23Z","timestamp":1760146403090,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo (FAPESP)","doi-asserted-by":"publisher","award":["2016\/21171-6","2019\/22175-3","2021\/00171-6","2022\/06176-2","405235\/2021-6"],"award-info":[{"award-number":["2016\/21171-6","2019\/22175-3","2021\/00171-6","2022\/06176-2","405235\/2021-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq)","award":["2016\/21171-6","2019\/22175-3","2021\/00171-6","2022\/06176-2","405235\/2021-6"],"award-info":[{"award-number":["2016\/21171-6","2019\/22175-3","2021\/00171-6","2022\/06176-2","405235\/2021-6"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>In South America, cutaneous leishmaniasis is caused by several species of the parasite of the genus Leishmania. Here, we describe an imported case of cutaneous leishmaniasis acquired in Peru by a Brazilian patient during her travel to Iquitos. Infection by Leishmania parasites was confirmed by histopathologic examination, and the patient was treated with pentavalent antimony (Pentostam), without clinical response. Molecular typing was performed by sequencing the ribosomal DNA internal transcribed spacer and heat-shock protein 70 gene, which identified the parasites as Leishmania guyanensis. The clinical isolate was similarly susceptible to amphotericin B, pentamidine, and miltefosine as the reference strain, while for pentavalent antimony, this clinical isolate was more susceptible than the reference strain, even though its susceptibility in vitro was still considered low. The patient was then treated with liposomal amphotericin B, with clinical improvement of the lesions.<\/jats:p>","DOI":"10.3390\/tropicalmed9110264","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T05:30:53Z","timestamp":1730784653000},"page":"264","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Imported Cutaneous Leishmaniasis from Peru Caused by Leishmania (Viannia) guyanensis in a Brazilian Patient: Case Report and In Vitro Drug Susceptibility Analysis"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8664-2009","authenticated-orcid":false,"given":"Elizabeth M.","family":"Coser","sequence":"first","affiliation":[{"name":"Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-862, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana I.","family":"Aoki","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-862, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiele","family":"Saborito","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-862, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephane","family":"de la Roca","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-862, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9752-377X","authenticated-orcid":false,"given":"Jo\u00e3o Paulo T.","family":"Brufatto","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-894, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Angerami","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-894, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael F.","family":"Stelini","sequence":"additional","affiliation":[{"name":"Departamento de Patologia, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-894, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Eduardo N. F.","family":"Velho","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-894, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0659-6269","authenticated-orcid":false,"given":"Adriano C.","family":"Coelho","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-862, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0140-6736(18)31204-2","article-title":"Leishmaniasis","volume":"392","author":"Burza","year":"2018","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Kato, H., C\u00e1ceres, A.G., Seki, C., Silupu Garc\u00eda, C.R., Holgu\u00edn Mauricci, C., Castro Mart\u00ednez, S.C., Moreno Paico, D., Castro Muniz, J.L., Troyes Rivera, L.D., and Villegas Briones, Z.I. 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