{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:32:44Z","timestamp":1790616764465,"version":"4.1.0"},"reference-count":34,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV), are endemic in the Mediterranean region. In France, several autochthonous cases of TOSV infection have been described, causing either meningitis or encephalitis. The aim of the present study was to investigate the seroprevalence of TOSV and SFSV antibodies in a healthy population from Corsica. In this cross-sectional study, participants were enrolled (i) from a medical staff at the University of Corsica and (ii) from general practitioners of the Corsican Sentinelles Network. The seroprevalence study was based on a virus microneutralization assay. A total of 240 sera were tested. Altogether, 54 sera (22.5%) were confirmed positive for TOSV antibodies, whereas none were positive for SFSV (0\/240). The residential district of participants was significantly associated with TOSV seropositivity (p value = 0.005). The rate of the seropositivity against TOSV in our study suggests that the Corsican population is well exposed to the TOSV. These results encourage the implementation of a systematic surveillance system including entomological, microbiological, and medical aspects for the collection of better information on the diseases that are associated with phleboviruses in Corsica and beyond in the regions where these viruses are present.<\/jats:p>","DOI":"10.3390\/v11090817","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T03:22:36Z","timestamp":1567653756000},"page":"817","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Circulation of Toscana Virus in a Sample Population of Corsica, France"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3659-4512","authenticated-orcid":false,"given":"Shirley","family":"Masse","sequence":"first","affiliation":[{"name":"Universit\u00e9 de Corse Pascal Paoli, EA7310 BIOSCOPE, 20250 Corte, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazli","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des Virus Emergents (UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection), 13385 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3618-1582","authenticated-orcid":false,"given":"Lisandru","family":"Capai","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Corse Pascal Paoli, EA7310 BIOSCOPE, 20250 Corte, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Bosseur","sequence":"additional","affiliation":[{"name":"Sciences Pour l\u2019Environnement\u2014UMR CNRS 6134, Universit\u00e9 de Corse, 20250 Corte, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"de Lamballerie","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des Virus Emergents (UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection), 13385 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-8251","authenticated-orcid":false,"given":"R\u00e9mi","family":"Charrel","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des Virus Emergents (UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection), 13385 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Falchi","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Corse Pascal Paoli, EA7310 BIOSCOPE, 20250 Corte, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"19507","DOI":"10.2807\/ese.15.10.19507-en","article-title":"Arthropod-borne viruses transmitted by Phlebotomine sandflies in Europe: A review","volume":"15","author":"Depaquit","year":"2010","journal-title":"Eurosurveillance"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.antiviral.2013.07.005","article-title":"Sandfly-borne phleboviruses of Eurasia and Africa: Epidemiology, genetic diversity, geographic range, control measures","volume":"100","author":"Alkan","year":"2013","journal-title":"Antivir. 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