{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:01:56Z","timestamp":1792065716689,"version":"4.4.0"},"reference-count":31,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["COV20\/00021"],"award-info":[{"award-number":["COV20\/00021"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Pregnant women are particularly vulnerable to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. In addition to unfavorable perinatal outcomes, there has been an increase in obstetric interventions. With this study, we aimed to clarify the reasons, using Robson\u2019s classification model, and risk factors for cesarean section (C-section) in SARS-CoV-2-infected mothers and their perinatal results. This was a prospective observational study that was carried out in 79 hospitals (Spanish Obstetric Emergency Group) with a cohort of 1704 SARS-CoV-2 PCR-positive pregnant women that were registered consecutively between 26 February and 5 November 2020. The data from 1248 pregnant women who delivered vaginally (vaginal + operative vaginal) was compared with those from 456 (26.8%) who underwent a C-section. C-section patients were older with higher rates of comorbidities, in vitro fertilization and multiple pregnancies (p &lt; 0.05) compared with women who delivered vaginally. Moreover, C-section risk was associated with the presence of pneumonia (p &lt; 0.001) and 41.1% of C-sections in patients with pneumonia were preterm (Robson\u2019s 10th category). However, delivery care was similar between asymptomatic and mild\u2013moderate symptomatic patients (p = 0.228) and their predisposing factors to C-section were the presence of uterine scarring (due to a previous C-section) and the induction of labor or programmed C-section for unspecified obstetric reasons. On the other hand, higher rates of hemorrhagic events, hypertensive disorders and thrombotic events were observed in the C-section group (p &lt; 0.001 for all three outcomes), as well as for ICU admission. These findings suggest that this type of delivery was associated with the mother\u2019s clinical conditions that required a rapid and early termination of pregnancy.<\/jats:p>","DOI":"10.3390\/v13112330","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T03:12:56Z","timestamp":1638328376000},"page":"2330","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["SARS-CoV-2 Infection and C-Section: A Prospective Observational Study"],"prefix":"10.3390","volume":"13","author":[{"given":"Eva","family":"Mor\u00e1n Antol\u00edn","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4214-0293","authenticated-orcid":false,"given":"Jos\u00e9 Rom\u00e1n","family":"Broull\u00f3n Molanes","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Puerta del Mar University Hospital, 1109 C\u00e1diz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Luisa","family":"de la Cruz Conty","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n de Investigaci\u00f3n Biom\u00e9dica, Puerta de Hierro University Hospital of Majadahonda, 28222 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Bego\u00f1a","family":"Encinas Pardilla","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Puerta de Hierro University Hospital of Majadahonda, 28222 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda del Pilar","family":"Guadix Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Virgen de la Macarena University Hospital, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9571-3219","authenticated-orcid":false,"given":"Jos\u00e9 Antonio","family":"Sainz Bueno","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, G. Chacon (Viamed Santa Angela de la Cruz Hospital), 41014 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Forc\u00e9n Acebal","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, 12 de Octubre University Hospital, 28041 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Pintado Recarte","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4077-912X","authenticated-orcid":false,"given":"Ana","family":"\u00c1lvarez Bartolom\u00e9","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Resuscitation, Puerta de Hierro University Hospital of Majadahonda, 28222 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Pedro","family":"Mart\u00ednez Cend\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Santa Lucia University Hospital, 30202 Cartagena, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1457-3446","authenticated-orcid":false,"given":"\u00d3scar","family":"Mart\u00ednez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Puerta de Hierro University Hospital of Majadahonda, 28222 Madrid, Spain"},{"name":"Medical Simulation Department, Universidad Cat\u00f3lica de Murcia, 30107 Murcia, Spain"},{"name":"Obstetric and Gynecology Department, Universidad Aut\u00f3noma de Madrid, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Spanish Obstetric Emergency Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"ref_1","unstructured":"WHO (2021, May 25). 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