{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:24:20Z","timestamp":1790663060724,"version":"4.1.0"},"reference-count":47,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T00:00:00Z","timestamp":1643328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006048","name":"University of the Republic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006048","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PEDECIBA"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Alphaviruses (Togaviridae) are arthropod-borne viruses responsible for several emerging diseases, maintained in nature through transmission between hematophagous arthropod vectors and susceptible vertebrate hosts. Although bats harbor many species of viruses, their role as reservoir hosts in emergent zoonoses has been verified only in a few cases. With bats being the second most diverse order of mammals, their implication in arbovirus infections needs to be elucidated. Reports on arbovirus infections in bats are scarce, especially in South American indigenous species. In this work, we report the genomic detection and identification of two different alphaviruses in oral swabs from bats captured in Northern Uruguay. Phylogenetic analysis identified R\u00edo Negro virus (RNV) in two different species: Tadarida brasiliensis (n = 6) and Myotis spp. (n = 1) and eastern equine encephalitis virus (EEEV) in Myotis spp. (n = 2). Previous studies of our group identified RNV and EEEV in mosquitoes and horse serology, suggesting that they may be circulating in enzootic cycles in our country. Our findings reveal that bats can be infected by these arboviruses and that chiropterans could participate in the viral natural cycle as virus amplifiers or dead-end hosts. Further studies are warranted to elucidate the role of these mammals in the biological cycle of these alphaviruses in Uruguay.<\/jats:p>","DOI":"10.3390\/v14020269","type":"journal-article","created":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T01:43:27Z","timestamp":1643420607000},"page":"269","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Alphavirus Identification in Neotropical Bats"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0859-8081","authenticated-orcid":false,"given":"Luc\u00eda","family":"Moreira Marrero","sequence":"first","affiliation":[{"name":"Secci\u00f3n Virolog\u00eda, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"},{"name":"Programa para la Conservaci\u00f3n de los Murci\u00e9lagos de Uruguay, Museo Nacional de Historia Natural, Montevideo 11000, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4055-9277","authenticated-orcid":false,"given":"Germ\u00e1n","family":"Botto Nu\u00f1ez","sequence":"additional","affiliation":[{"name":"Programa para la Conservaci\u00f3n de los Murci\u00e9lagos de Uruguay, Museo Nacional de Historia Natural, Montevideo 11000, Uruguay"},{"name":"Departamento de M\u00e9todos Cuantitativos, Facultad de Medicina, Universidad de la Rep\u00fablica, Montevideo 11800, Uruguay"},{"name":"Departamento de Biodiversidad y Gen\u00e9tica, Instituto de Investigaciones Biol\u00f3gicas Clemente, Montevideo 11600, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Frabasile","sequence":"additional","affiliation":[{"name":"Secci\u00f3n Virolog\u00eda, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3701-9621","authenticated-orcid":false,"given":"Adriana","family":"Delfraro","sequence":"additional","affiliation":[{"name":"Secci\u00f3n Virolog\u00eda, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/nrmicro1006","article-title":"Transmission cycles, host range, evolution and emergence of arboviral disease","volume":"2","author":"Weaver","year":"2004","journal-title":"Nat. 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