{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T22:04:41Z","timestamp":1768514681358,"version":"3.49.0"},"reference-count":80,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T00:00:00Z","timestamp":1646438400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["RC IZSVE 03\/20"],"award-info":[{"award-number":["RC IZSVE 03\/20"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of Health","award":["B29C20000250001"],"award-info":[{"award-number":["B29C20000250001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Norovirus, an ssRNA + virus of the family Caliciviridae, is a leading disease burden in humans worldwide, causing an estimated 600 million cases of acute gastroenteritis every year. Since the discovery of norovirus in the faeces of swine in Japan in the 1990s, swine norovirus has been reported in several countries on several continents. The identification of the human-associated GII.4 genotype in swine has raised questions about this animal species as a reservoir of norovirus with zoonotic potential, even if species-specific P-types are usually detected in swine. This review summarises the available data regarding the geographic distribution of norovirus in swine, the years of detection, the genotype characterisation, and the prevalence in specific production groups. Furthermore, we discuss the major bottlenecks for the detection and characterisation of swine noroviruses.<\/jats:p>","DOI":"10.3390\/v14030537","type":"journal-article","created":{"date-parts":[[2022,3,6]],"date-time":"2022-03-06T20:40:38Z","timestamp":1646599238000},"page":"537","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Swine Norovirus: Past, Present, and Future"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6464-5065","authenticated-orcid":false,"given":"Lara","family":"Cavicchio","sequence":"first","affiliation":[{"name":"Diagnostic Virology Laboratory, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVE), Viale dell\u2019Universit\u00e0 10, Legnaro, 35020 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0102-7021","authenticated-orcid":false,"given":"Andrea","family":"Laconi","sequence":"additional","affiliation":[{"name":"Department of Comparative Biomedicine and Food Science, University of Padua, Viale dell\u2019Universit\u00e0 16, Legnaro, 35020 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6207-4721","authenticated-orcid":false,"given":"Alessandra","family":"Piccirillo","sequence":"additional","affiliation":[{"name":"Department of Comparative Biomedicine and Food Science, University of Padua, Viale dell\u2019Universit\u00e0 16, Legnaro, 35020 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5891-1267","authenticated-orcid":false,"given":"Maria Serena","family":"Beato","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for African Swine Fever and Ruminant retroviruses, Istituto Zooprofilattico Sperimentale dell\u2019Umbria e delle Marche (IZSUM), Via G. Salvemini, 1, 06126 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1073\/pnas.1522680112","article-title":"Opinion: Specimen collections should have a much bigger role in infectious disease research and response","volume":"113","author":"DiEuliis","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_2","unstructured":"(2021, December 29). Norovirus Worldwide|CDC, Available online: https:\/\/www.cdc.gov\/norovirus\/trends-outbreaks\/worldwide.html."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"European Food Safety Autority (EFSA) (2021). The European Union One Health 2020 Zoonoses Report. EFSA J., 19, e06971.","DOI":"10.2903\/j.efsa.2021.6971"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Gosh, S., Malik, S.Y., and Kobayashi, N. (2020). Animal Caliciviruses. Animal\u2014Origin Viral Zoonoses, Livestock Diseases Singapore, Springer.","DOI":"10.1007\/978-981-15-2651-0"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1099\/vir.0.059634-0","article-title":"Norovirus gene expression and replication","volume":"95 Pt 2","author":"Thorne","year":"2014","journal-title":"J. Gen. Virol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e2134","DOI":"10.7717\/peerj.2134","article-title":"Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteins","volume":"4","author":"Olspert","year":"2016","journal-title":"PeerJ"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"11603","DOI":"10.1128\/JVI.77.21.11603-11615.2003","article-title":"The 3\u2032 End of Norwalk Virus mRNA Contains Determinants That Regulate the Expression and Stability of the Viral Capsid Protein VP1: A Novel Function for the VP2 Protein","volume":"77","author":"Crawford","year":"2003","journal-title":"J. Virol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1093\/nar\/gkn096","article-title":"Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses","volume":"36","author":"Simmonds","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1099\/00222615-11-4-441","article-title":"Isolation of Small Viruses Resembling Astroviruses and Caliciviruses from Acute Enteritis of Calves","volume":"11","author":"Woode","year":"1978","journal-title":"J. Med. Microbiol."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Bhar, S., and Jones, M.K. (2019). In Vitro Replication of Human Norovirus. Viruses, 11.","DOI":"10.3390\/v11060547"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1126\/science.aaf5211","article-title":"Replication of human noroviruses in stem cell-derived human enteroids","volume":"353","author":"Ettayebi","year":"2016","journal-title":"Science"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e01136-20","DOI":"10.1128\/mSphere.01136-20","article-title":"New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids","volume":"6","author":"Ettayebi","year":"2021","journal-title":"mSphere"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"5453","DOI":"10.1016\/j.vaccine.2006.12.032","article-title":"Porcine enteric caliciviruses: Genetic and antigenic relatedness to human caliciviruses, diagnosis and epidemiology","volume":"25","author":"Wang","year":"2007","journal-title":"Vaccine"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"10372","DOI":"10.1128\/JVI.00809-06","article-title":"Pathogenesis of a Genogroup II Human Norovirus in Gnotobiotic Pigs","volume":"80","author":"Cheetham","year":"2006","journal-title":"J. Virol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.4014\/jmb.1810.09061","article-title":"Pathogenesis of Human Norovirus Genogroup II Genotype 4 in Post-Weaning Gnotobiotic Pigs","volume":"28","author":"Park","year":"2018","journal-title":"J. Microbiol. Biotechnol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1099\/vir.0.054080-0","article-title":"Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age","volume":"94","author":"Bui","year":"2013","journal-title":"J. Gen. Virol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"9183","DOI":"10.1128\/JVI.00558-07","article-title":"Cytokine and Antibody Responses in Gnotobiotic Pigs after Infection with Human Norovirus Genogroup II.4 (HS66 Strain)","volume":"81","author":"Souza","year":"2007","journal-title":"J. Virol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ludwig-Begall, L., Mauroy, A., and Thiry, E. (2021). Noroviruses\u2014The State of the Art, Nearly Fifty Years after Their Initial Discovery. Viruses, 13.","DOI":"10.3390\/v13081541"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s007050050369","article-title":"Detection of Norwalk-like virus genes in the caecum contents of pigs","volume":"143","author":"Sugieda","year":"1998","journal-title":"Arch. Virol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1128\/JCM.43.2.657-661.2005","article-title":"Seroprevalence of Noroviruses in Swine","volume":"43","author":"Farkas","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1128\/JCM.00341-08","article-title":"Identification of a Porcine Calicivirus Related Genetically to Human Sapoviruses","volume":"46","author":"Martella","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s11262-008-0198-0","article-title":"Genetic heterogeneity of porcine enteric caliciviruses identified from diarrhoeic piglets","volume":"36","author":"Martella","year":"2008","journal-title":"Virus Genes"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e00344-13","DOI":"10.1128\/genomeA.00344-13","article-title":"First Complete Genome Sequence of a Genogroup II Genotype 18 Porcine Norovirus, Strain QW125","volume":"1","author":"Oka","year":"2013","journal-title":"Genome Announc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1007\/s00705-014-2076-5","article-title":"Detection and characterization of porcine caliciviruses in Italy","volume":"159","author":"Tofani","year":"2014","journal-title":"Arch. Virol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s11250-014-0685-3","article-title":"High frequency of porcine norovirus infection in finisher units of Brazilian pig-production systems","volume":"47","author":"Silva","year":"2015","journal-title":"Trop. Anim. Health Prod."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1111\/tbed.12582","article-title":"Risk Profile of Hepatitis E Virus from Pigs or Pork in Canada","volume":"64","author":"Wilhelm","year":"2017","journal-title":"Transbound. Emerg. Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1007\/s00705-015-2538-4","article-title":"Detection and molecular characterization of zoonotic viruses in swine fecal samples in Italian pig herds","volume":"160","author":"Monini","year":"2015","journal-title":"Arch. Virol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"9217","DOI":"10.1038\/s41598-020-66140-4","article-title":"Unrevealed genetic diversity of GII Norovirus in the swine population of North East Italy","volume":"10","author":"Cavicchio","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.rvsc.2009.12.013","article-title":"First detection of porcine norovirus GII.18 in Latin America","volume":"89","author":"Cunha","year":"2010","journal-title":"Res. Vet. Sci."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s00705-010-0695-z","article-title":"Genetic diversity of porcine enteric caliciviruses in pigs raised in Rio de Janeiro State, Brazil","volume":"155","author":"Cunha","year":"2010","journal-title":"Arch. Virol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1017\/S0950268809990872","article-title":"Enteric calicivirus and rotavirus infections in domestic pigs","volume":"138","author":"Halaihel","year":"2010","journal-title":"Epidemiol. Infect."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1007\/s00705-009-0501-y","article-title":"Porcine noroviruses and sapoviruses on Korean swine farms","volume":"154","author":"Keum","year":"2009","journal-title":"Arch. Virol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.vetmic.2013.10.018","article-title":"Detection and characterization of potentially zoonotic viruses in faeces of pigs at slaughter in Germany","volume":"168","author":"Machnowska","year":"2014","journal-title":"Vet. Microbiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.meegid.2009.11.010","article-title":"Detection and molecular characterisation of noroviruses and sapoviruses in asymptomatic swine and cattle in Slovenian farms","volume":"10","author":"Mijovski","year":"2010","journal-title":"Infect. Genet. Evol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1128\/JCM.02130-09","article-title":"Frequent Detection of Noroviruses and Sapoviruses in Swine and High Genetic Diversity of Porcine Sapovirus in Japan during Fiscal Year 2008","volume":"48","author":"Nakamura","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"305","DOI":"10.6090\/jarq.53.305","article-title":"Detection Frequency of Porcine Noroviruses in Healthy Pigs in Japan","volume":"53","author":"Okada","year":"2019","journal-title":"Jpn. Agric. Res. Q. JARQ"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s00705-006-0887-8","article-title":"Enteric caliciviruses in domestic pigs in Hungary","volume":"152","author":"Reuter","year":"2007","journal-title":"Arch. Virol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1007\/s00705-009-0487-5","article-title":"Molecular detection and prevalence of porcine caliciviruses in eastern China from 2008 to 2009","volume":"154","author":"Shen","year":"2009","journal-title":"Arch. Virol."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Shen, Q., Zhang, W., Yang, S., Yang, Z., Chen, Y., Cui, L., Zhu, J., and Hua, X. (2012). Recombinant porcine norovirus identified from piglet with diarrhea. BMC Vet. Res., 8.","DOI":"10.1186\/1746-6148-8-155"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1007\/s00705-013-1619-5","article-title":"Prevalence and molecular characterization of porcine enteric caliciviruses and first detection of porcine kobuviruses in US swine","volume":"158","author":"Sisay","year":"2013","journal-title":"Arch. Virol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1007\/s00705-016-2974-9","article-title":"First detection and molecular characterization of sapoviruses and noroviruses with zoonotic potential in swine in Ethiopia","volume":"161","author":"Sisay","year":"2016","journal-title":"Arch. Virol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1556\/004.2019.016","article-title":"Frequency of diarrhoea-associated viruses in swine of various ages in Hungary","volume":"67","author":"Marosi","year":"2019","journal-title":"Acta Vet. Hung."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jviromet.2005.10.003","article-title":"Development of a new microwell hybridization assay and an internal control RNA for the detection of porcine noroviruses and sapoviruses by reverse transcription-PCR","volume":"132","author":"Wang","year":"2006","journal-title":"J. Virol. Methods"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1007\/s00705-008-0189-4","article-title":"Noroviruses and sapoviruses in pigs in Belgium","volume":"153","author":"Mauroy","year":"2008","journal-title":"Arch. Virol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40813-021-00245-8","article-title":"Epidemiology of Astrovirus, Norovirus and Sapovirus in Greek pig farms indicates high prevalence of Mamastrovirus suggesting the potential need for systematic surveillance","volume":"8","author":"Stamelou","year":"2022","journal-title":"Porc. Health Manag."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1863-2378.2012.01483.x","article-title":"Detection of Multiple Genotypes of Calicivirus Infection in Asymptomatic Swine in Taiwan","volume":"59","author":"Chao","year":"2012","journal-title":"Zoonoses Public Health"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.vetmic.2006.03.016","article-title":"Molecular detection of porcine enteric caliciviruses in Venezuelan farms","volume":"116","author":"Alcala","year":"2006","journal-title":"Vet. Microbiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s40813-020-00147-1","article-title":"Identification of two divergent swine Noroviruses detected at the slaughterhouse in North East Italy","volume":"6","author":"Laconi","year":"2020","journal-title":"Porc. Health Manag."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.3201\/eid\/1706.101756","article-title":"Characterization and prevalence of a new porcine calicivirus in Swine, United States","volume":"17","author":"Wang","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1128\/JCM.00865-13","article-title":"Prevalence of Porcine Noroviruses, Molecular Characterization of Emerging Porcine Sapoviruses from Finisher Swine in the United States, and Unified Classification Scheme for Sapoviruses","volume":"51","author":"Scheuer","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ijfoodmicro.2014.05.006","article-title":"Survey of Canadian retail pork chops and pork livers for detection of hepatitis E virus, norovirus, and rotavirus using real time RT-PCR","volume":"185","author":"Wilhelm","year":"2014","journal-title":"Int. J. Food Microbiol."},{"key":"ref_52","first-page":"459","article-title":"Prevalence of hepatitis E virus and porcine caliciviruses in pig farms of Guizhou province, China","volume":"11","author":"Shen","year":"2011","journal-title":"Zahedan J. Res. Med. Sci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"7015","DOI":"10.1128\/JVI.00757-12","article-title":"Complete Genome Sequence of a New-Genotype Porcine Norovirus Isolated from Piglets with Diarrhea","volume":"86","author":"Shen","year":"2012","journal-title":"J. Virol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e00014-20","DOI":"10.1128\/MRA.00014-20","article-title":"Near-Complete Genome Sequence of a Swine Norovirus GII.11 Strain Detected in Japan in 2018","volume":"9","author":"Okada","year":"2020","journal-title":"Microbiol. Resour. Announc."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1017\/S0950268800052663","article-title":"Outbreaks of Norwalk-like virus-associated gastroenteritis traced to shellfish: Coexistence of two genotypes in one specimen","volume":"116","author":"Sugieda","year":"1996","journal-title":"Epidemiol. Infect."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0168-1702(02)00107-7","article-title":"Viruses detected in the caecum contents of healthy pigs representing a new genetic cluster in genogroup II of the genus \u2018Norwalk-like viruses\u2019","volume":"87","author":"Sugieda","year":"2002","journal-title":"Virus Res."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00705-009-0344-6","article-title":"Genetic diversity of porcine Norovirus and Sapovirus: Canada, 2005\u20132007","volume":"154","author":"Sansregret","year":"2009","journal-title":"Arch. Virol."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Schuele, L., Lizarazo-Forero, E., Strutzberg-Minder, K., Sch\u00fctze, S., L\u00f6bert, S., Lambrecht, C., Harlizius, J., Friedrich, A.W., Peter, S., and Rossen, J.W.A. (2021). Application of shotgun metagenomics sequencing and targeted sequence capture to detect circulating porcine viruses in the Dutch\u2013German border region. Transbound. Emerg. Dis., 1\u201314.","DOI":"10.1111\/tbed.14249"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3201\/eid0601.000106","article-title":"Norwalk-like calicivirus genes in farm animals","volume":"6","author":"Herrera","year":"2000","journal-title":"Emerg. Infect. Dis."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijfoodmicro.2015.04.036","article-title":"Presence of pathogenic enteric viruses in illegally imported meat and meat products to EU by international air travelers","volume":"209","author":"Gallego","year":"2015","journal-title":"Int. J. Food Microbiol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.3201\/eid1308.070005","article-title":"Human Noroviruses in Swine and Cattle","volume":"13","author":"Mattison","year":"2007","journal-title":"Emerg. Infect. Dis."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s11262-011-0588-6","article-title":"Identification of genetic diversity of porcine Norovirus and Sapovirus in Korea","volume":"42","author":"Song","year":"2011","journal-title":"Virus Genes"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.fm.2009.03.011","article-title":"Broad range RT-PCR assays targeting human noroviruses also detect swine noroviruses","volume":"26","author":"Sansregret","year":"2009","journal-title":"Food Microbiol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.vetmic.2008.06.019","article-title":"Molecular detection of norovirus in sheep and pigs in New Zealand farms","volume":"133","author":"Wolf","year":"2009","journal-title":"Vet. Microbiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/s12275-021-1218-1","article-title":"Comparative study of the geographical spread of genogroup II porcine norovirus and human norovirus","volume":"59","author":"Koo","year":"2021","journal-title":"J. Microbiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"168","DOI":"10.11144\/javeriana.SC16-2.iohn","article-title":"Identificaci\u00f3n de Norovirus Humano (HNoV) en muestras de esti\u00e9rcol de cerdos dom\u00e9sticos","volume":"16","author":"Ruiz","year":"2011","journal-title":"Univ. Sci."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/zph.12269","article-title":"Seroprevalence in Household Raised Pigs Indicate High Exposure to GII Noroviruses in Rural Nicaragua","volume":"63","author":"Bucardo","year":"2016","journal-title":"Zoonoses Public Health"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/1096-9071(200010)62:2<217::AID-JMV13>3.0.CO;2-F","article-title":"Prevalence and genetic diversity of human caliciviruses (HuCVs) in Mexican children","volume":"62","author":"Farkas","year":"2000","journal-title":"J. Med. Virol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1099\/jgv.0.001318","article-title":"Updated classification of norovirus genogroups and genotypes","volume":"100","author":"Chhabra","year":"2019","journal-title":"J. Gen. Virol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.tifs.2021.06.027","article-title":"Current state-of-the-art diagnostics for Norovirus detection: Model approaches for point-of-care analysis","volume":"114","author":"Beizaei","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s11262-009-0360-3","article-title":"Genomic characterization of swine caliciviruses representing a new genus of Caliciviridae","volume":"39","author":"Sansregret","year":"2009","journal-title":"Virus Genes"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/jmv.20403","article-title":"Evidence of the etiological predominance of norovirus in gastroenteritis outbreaks\u2014Emerging new-variant and recombinant noroviruses in Hungary","volume":"76","author":"Reuter","year":"2005","journal-title":"J. Med. Virol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"vez048","DOI":"10.1093\/ve\/vez048","article-title":"Emergence of norovirus strains: A tale of two genes","volume":"5","author":"Parra","year":"2019","journal-title":"Virus Evol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1128\/JVI.01306-06","article-title":"Binding Patterns of Human Norovirus-Like Particles to Buccal and Intestinal Tissues of Gnotobiotic Pigs in Relation to A\/H Histo-Blood Group Antigen Expression","volume":"81","author":"Cheetham","year":"2007","journal-title":"J. Virol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"3234","DOI":"10.1128\/JCM.00305-11","article-title":"Characterization of Emerging GII.g\/GII.12 Noroviruses from a Gastroenteritis Outbreak in the United States in 2010","volume":"49","author":"Takanashi","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1128\/CVI.00196-15","article-title":"Serological Correlates of Protection against a GII.4 Norovirus","volume":"22","author":"Atmar","year":"2015","journal-title":"Clin. Vaccine Immunol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jviromet.2005.01.018","article-title":"The use of endogenous and exogenous reference RNAs for qualitative and quantitative detection of PRRSV in porcine semen","volume":"126","author":"Wallner","year":"2005","journal-title":"J. Virol. Methods"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1128\/JCM.39.1.196-200.2001","article-title":"Simultaneous detection of influenza viruses A and B using real-time quantitative PCR","volume":"39","author":"Nijhuis","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"8441","DOI":"10.1038\/s41598-020-64003-6","article-title":"Detection of avian influenza virus: A comparative study of the in silico and in vitro performances of current RT-qPCR assays","volume":"10","author":"Laconi","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1128\/JCM.42.2.835-836.2004","article-title":"Primer Pair p289\u2013p290, Designed to Detect Both Noroviruses and Sapoviruses by Reverse Transcription-PCR, Also Detects Rotaviruses by Cross-Reactivity","volume":"42","author":"Ludert","year":"2004","journal-title":"J. Clin. Microbiol."}],"container-title":["Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-4915\/14\/3\/537\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:32:39Z","timestamp":1760135559000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-4915\/14\/3\/537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,5]]},"references-count":80,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["v14030537"],"URL":"https:\/\/doi.org\/10.3390\/v14030537","relation":{},"ISSN":["1999-4915"],"issn-type":[{"value":"1999-4915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,5]]}}}