{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T03:01:39Z","timestamp":1760151699681,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006083","name":"Ministry of Defence","doi-asserted-by":"publisher","award":["Not Listed"],"award-info":[{"award-number":["Not Listed"]}],"id":[{"id":"10.13039\/501100006083","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Countermeasure Systems Joint Project Management Office","award":["HDTRA1-11-C-0039"],"award-info":[{"award-number":["HDTRA1-11-C-0039"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>During outbreaks of virus diseases, many variants may appear, some of which may be of concern. Stability in an aerosol of several Ebola virus and Marburg virus variants was investigated. Studies were performed measuring aerosol survival using the Goldberg drum but no significant difference in biological decay rates between variants was observed. In addition, historic data on virulence in a murine model of different Ebola virus variants were compared to newly presented data for Ebola virus Kikwit in the A129 Interferon alpha\/beta receptor-deficient mouse model. Ebola virus Kikwit was less virulent than Ebola virus Ecran in our mouse model. The mouse model may be a useful tool for studying differences in virulence associated with different variants whereas aerosol stability studies may not need to be conducted beyond the species level.<\/jats:p>","DOI":"10.3390\/v14040780","type":"journal-article","created":{"date-parts":[[2022,4,10]],"date-time":"2022-04-10T06:02:54Z","timestamp":1649570574000},"page":"780","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in an Immune-Deficient Mouse"],"prefix":"10.3390","volume":"14","author":[{"given":"Sophie J.","family":"Smither","sequence":"first","affiliation":[{"name":"Microbiology and Aerosol Sciences Group, CBR Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, Salisbury SP4 0JQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin S.","family":"Eastaugh","sequence":"additional","affiliation":[{"name":"Microbiology and Aerosol Sciences Group, CBR Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, Salisbury SP4 0JQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"Lever","sequence":"additional","affiliation":[{"name":"Microbiology and Aerosol Sciences Group, CBR Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, Salisbury SP4 0JQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2100348","DOI":"10.2807\/1560-7917.ES.2021.26.16.2100348","article-title":"Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: Data from seven EU\/EEA countries, weeks 38\/2020 to 10\/2021","volume":"26","author":"Funk","year":"2021","journal-title":"Eurosurveillance"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.chom.2021.02.020","article-title":"The variant gambit: COVID-19\u2019s next move","volume":"29","author":"Plante","year":"2021","journal-title":"Cell Host Microbe"},{"key":"ref_3","unstructured":"(2021, July 20). 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