{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:27:59Z","timestamp":1790947679906,"version":"4.1.0"},"reference-count":58,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003323","name":"Agence Nationale de Recherches sur le Sida et les H\u00e9patites Virales","doi-asserted-by":"publisher","award":["ANRS-COV10"],"award-info":[{"award-number":["ANRS-COV10"]}],"id":[{"id":"10.13039\/501100003323","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-16-IDEX-0006"],"award-info":[{"award-number":["ANR-16-IDEX-0006"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"name":"French Minister of Europe and Foreign Affairs","award":["FSPI-2019"],"award-info":[{"award-number":["FSPI-2019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Background: Studies have linked bats to outbreaks of viral diseases in human populations such as SARS-CoV-1 and MERS-CoV and the ongoing SARS-CoV-2 pandemic. Methods: We carried out a longitudinal survey from August 2020 to July 2021 at two sites in Zimbabwe with bat\u2013human interactions: Magweto cave and Chirundu farm. A total of 1732 and 1866 individual bat fecal samples were collected, respectively. Coronaviruses and bat species were amplified using PCR systems. Results: Analysis of the coronavirus sequences revealed a high genetic diversity, and we identified different sub-viral groups in the Alphacoronavirus and Betacoronavirus genus. The established sub-viral groups fell within the described Alphacoronavirus sub-genera: Decacovirus, Duvinacovirus, Rhinacovirus, Setracovirus and Minunacovirus and for Betacoronavirus sub-genera: Sarbecoviruses, Merbecovirus and Hibecovirus. Our results showed an overall proportion for CoV positive PCR tests of 23.7% at Chirundu site and 16.5% and 38.9% at Magweto site for insectivorous bats and Macronycteris gigas, respectively. Conclusions: The higher risk of bat coronavirus exposure for humans was found in December to March in relation to higher viral shedding peaks of coronaviruses in the parturition, lactation and weaning months of the bat populations at both sites. We also highlight the need to further document viral infectious risk in human\/domestic animal populations surrounding bat habitats in Zimbabwe.<\/jats:p>","DOI":"10.3390\/v14040781","type":"journal-article","created":{"date-parts":[[2022,4,10]],"date-time":"2022-04-10T06:02:54Z","timestamp":1649570574000},"page":"781","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Longitudinal Survey of Coronavirus Circulation and Diversity in Insectivorous Bat Colonies in Zimbabwe"],"prefix":"10.3390","volume":"14","author":[{"given":"Vimbiso","family":"Chidoti","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Science, University of Zimbabwe, Harare P.O. Box MP 167, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2942-4531","authenticated-orcid":false,"given":"H\u00e9l\u00e8ne","family":"De Nys","sequence":"additional","affiliation":[{"name":"ASTRE, CIRAD, INRAE, University of Montpellier, 34980 Montpellier, France"},{"name":"CIRAD, UMR ASTRE, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Pinarello","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Zimbabwe, Harare P.O. Box MP 167, Zimbabwe"},{"name":"ASTRE, CIRAD, INRAE, University of Montpellier, 34980 Montpellier, France"},{"name":"CIRAD, UMR ASTRE, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Getrude","family":"Mashura","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Zimbabwe, Harare P.O. 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Box MP 167, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7668-1971","authenticated-orcid":false,"given":"Julien","family":"Cappelle","sequence":"additional","affiliation":[{"name":"ASTRE, CIRAD, INRAE, University of Montpellier, 34980 Montpellier, France"},{"name":"CIRAD, UMR ASTRE, 34398 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngoni","family":"Chiweshe","sequence":"additional","affiliation":[{"name":"CIRAD, UMR ASTRE, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5081-1632","authenticated-orcid":false,"given":"Ahidjo","family":"Ayouba","sequence":"additional","affiliation":[{"name":"TransVIHMI, University of Montpellier, IRD, Inserm, 34394 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gift","family":"Matope","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Zimbabwe, Harare P.O. 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Available online: https:\/\/talk.ictvonline.org\/."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1016\/j.sjbs.2020.04.033","article-title":"Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Emergence, history, basic and clinical aspects","volume":"27","year":"2020","journal-title":"Saudi J. Biol. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/bs.aivir.2018.01.001","article-title":"Hosts and Sources of Endemic Human Coronaviruses","volume":"100","author":"Corman","year":"2018","journal-title":"Adv. Virus Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.virol.2014.11.026","article-title":"Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China","volume":"476","author":"Li","year":"2015","journal-title":"Virology"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Monchatre-Leroy, E., Bou\u00e9, F., Boucher, J.M., Renault, C., Moutou, F., Gouilh, M.A., and Umhang, G. (2017). Identification of alpha and beta coronavirus in wildlife species in france: Bats, rodents, rabbits, and hedgehogs. Viruses, 9.","DOI":"10.3390\/v9120364"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.1128\/JVI.03273-12","article-title":"A Case for the Ancient Origin of Coronaviruses","volume":"87","author":"Wertheim","year":"2013","journal-title":"J. Virol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1128\/jcm.12.3.462-468.1980","article-title":"Infectivity of human coronavirus strain 229E","volume":"12","author":"Macnaughton","year":"1980","journal-title":"J. Clin. Microbiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nm1024","article-title":"Identification of a new human coronavirus","volume":"10","author":"Pyrc","year":"2004","journal-title":"Nat. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12985-015-0271-y","article-title":"Detection of new genetic variants of Betacoronaviruses in Endemic Frugivorous Bats of Madagascar","volume":"12","author":"Razanajatovo","year":"2015","journal-title":"Virol. J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.virol.2006.02.041","article-title":"Molecular diversity of coronaviruses in bats","volume":"351","author":"Woo","year":"2006","journal-title":"Virology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12985-015-0422-1","article-title":"Bat origin of human coronaviruses: Emerging and re-emerging pathogens in humans and animals Susanna Lau Positive-strand RNA viruses","volume":"12","author":"Hu","year":"2015","journal-title":"Virol. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fvets.2021.643220","article-title":"Bovine Coronavirus and the Associated Diseases","volume":"8","author":"Vlasova","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.3181\/0903-MR-94","article-title":"Coronavirus Diversity, Phylogeny and Interspecies Jumping","volume":"234","author":"Woo","year":"2009","journal-title":"Exp. Biol. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1111\/ele.12491","article-title":"Network analysis of host\u2014Virus communities in bats and rodents reveals determinants of cross-species transmission","volume":"18","author":"Luis","year":"2015","journal-title":"Ecol. Lett."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/ncomms1796","article-title":"Bats host major mammalian paramyxoviruses","volume":"3","author":"Drexler","year":"2012","journal-title":"Nat. Commun."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"S88","DOI":"10.1038\/nm1143","article-title":"Severe acute respiratory syndrome","volume":"10","author":"Peiris","year":"2004","journal-title":"Nat. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"19589","DOI":"10.1007\/s11356-021-12553-1","article-title":"Coronaviruses in humans and animals: The role of bats in viral evolution","volume":"28","author":"Kamel","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/jmv.25731","article-title":"Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2","volume":"92","author":"Li","year":"2020","journal-title":"J. Med. Virol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"6563","DOI":"10.1038\/s41467-021-26809-4","article-title":"A novel SARS-CoV-2 related coronavirus in bats from Cambodia","volume":"12","author":"Delaune","year":"2021","journal-title":"Nat. Commun."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/jzo.12769","article-title":"Bat-borne viruses in Africa: A critical review","volume":"311","author":"Coertse","year":"2020","journal-title":"J. Zool."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.virol.2018.01.014","article-title":"SARS-CoV related Betacoronavirus and diverse Alphacoronavirus members found in western old-world","volume":"517","author":"Puechmaille","year":"2018","journal-title":"Virology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41579-020-0394-z","article-title":"Bat-borne virus diversity, spillover and emergence","volume":"18","author":"Letko","year":"2020","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Woo, P.C.Y., and Lau, S.K.P. (2019). Viruses and Bats. Viruses, 11.","DOI":"10.3390\/v11100884"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-020-17687-3","article-title":"Origin and cross-species transmission of bat coronaviruses in China","volume":"11","author":"Latinne","year":"2020","journal-title":"Nat. Commun."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1128\/CMR.00017-06","article-title":"Bats: Important Reservoir Hosts of Emerging Viruses","volume":"19","author":"Calisher","year":"2006","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_27","unstructured":"Newman, S., Field, H., de Jong, C., and Epstein, J.H. (2011). Investigating the Role of Bats in Emerging Zoonoses: Balancing Ecology, Conservation and Public Health Interests, FAO. FAO Animal."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Alfelt, A., Devaux, C., Serra-Cobo, J., and Frutos, R. (2018). Bats, Bat-Borne Viruses, and Environmental Changes. Bats, IntechOpen.","DOI":"10.5772\/intechopen.74377"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-018-0950-6","article-title":"Longitudinal study of age-specific pattern of coronavirus infection in Lyle\u2019s flying fox (Pteropus lylei) in Thailand","volume":"15","author":"Wacharapluesadee","year":"2018","journal-title":"Virol. J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ve\/vex012","article-title":"Global patterns in coronavirus diversity","volume":"3","author":"Anthony","year":"2017","journal-title":"Virus Evol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-03169-z","article-title":"Longitudinal monitoring in Cambodia suggests higher circulation of alpha and betacoronaviruses in juvenile and immature bats of three species","volume":"11","author":"Cappelle","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Banerjee, A., Kulcsar, K., Misra, V., Frieman, M., and Mossman, K. (2019). Bats and coronaviruses. Viruses, 11.","DOI":"10.3389\/fimmu.2020.00026"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.meegid.2018.01.007","article-title":"Circulation of Alphacoronavirus, Betacoronavirus and Paramyxovirus in Hipposideros bat species in Zimbabwe","volume":"58","author":"Bourgarel","year":"2018","journal-title":"Infect. Genet. Evol."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Bourgarel, M., No\u00ebl, V., Pfukenyi, D., Michaux, J., Andr\u00e9, A., Becquart, P., Cerqueira, F., Barrachina, C., Bou\u00e9, V., and Talignani, L. (2019). Next-generation sequencing on insectivorous bat guano: An accurate tool to identify arthropod viruses of potential agricultural concern. Viruses, 11.","DOI":"10.3390\/v11121102"},{"key":"ref_35","unstructured":"Monadjem, A., Taylor, P.J., Cotterill, F.P.D., and Schoeman, M. (2010). Bats of Southern and Central Africa: A Biogeographic and Taxonomic Synthesis, Wits University Press."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.3201\/eid2412.180740","article-title":"Survey of ebola viruses in frugivorous and insectivorous bats in Guinea, Cameroon, and the democratic republic of the Congo, 2015\u20132017","volume":"24","author":"Keita","year":"2018","journal-title":"Emerg. Infect. Dis."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"12815","DOI":"10.1128\/JVI.05838-11","article-title":"Avian coronavirus in wild aquatic birds","volume":"85","author":"Chu","year":"2011","journal-title":"J. Virol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"W232","DOI":"10.1093\/nar\/gkw256","article-title":"W-IQ-TREE: A fast online phylogenetic tool for maximum likelihood analysis","volume":"44","author":"Trifinopoulos","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1046\/j.1365-294X.2004.02106.x","article-title":"Divergence dates for Malagasy lemurs estimated from multiple gene loci: Geological and evolutionary context","volume":"13","author":"Yoder","year":"2004","journal-title":"Mol. Ecol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1073\/pnas.86.16.6196","article-title":"Dynamics of mitochondrial DNA evolution in animals: Amplification and sequencing with conserved primers","volume":"86","author":"Kocher","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_42","first-page":"119","article-title":"Approximate Is Better than \u201cExact\u201d for Interval Estimation of Binomial Proportions","volume":"52","author":"Agresti","year":"1998","journal-title":"Am. Stat."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Geldenhuys, M., Mortlock, M., Epstein, J.H., Paw\u0119ska, J.T., Weyer, J., and Markotter, W. (2021). Overview of Bat and Wildlife Coronavirus Surveillance in Africa: A Framework for Global Investigations. Viruses, 13.","DOI":"10.3390\/v13050936"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s10393-017-1245-x","article-title":"Seasonal Fluctuations of Astrovirus, But Not Coronavirus Shedding in Bats Inhabiting Human-Modified Tropical Forests","volume":"14","author":"Seltmann","year":"2017","journal-title":"EcoHealth"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3201\/eid1703.100526","article-title":"Amplification of emerging viruses in a bat colony","volume":"17","author":"Drexler","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"ref_46","first-page":"1","article-title":"Reproduction of East-African bats may guide risk mitigation for coronavirus spillover","volume":"8","author":"Goldstein","year":"2020","journal-title":"One Health Outlook"},{"key":"ref_47","unstructured":"Van Cakenberghe, V., and Seamark, E. (2020). African Chiroptera Report 2020, AfricanBats NPC."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Wong, A.C.P., Li, X., Lau, S.K.P., and Woo, P.C.Y. (2019). Global epidemiology of bat coronaviruses. Viruses, 11.","DOI":"10.3390\/v11020174"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1099\/vir.0.049759-0","article-title":"Coronaviruses in bats from Mexico","volume":"94","author":"Anthony","year":"2013","journal-title":"J. Gen. Virol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3201\/eid1903.121503","article-title":"Human betacoronavirus 2c EMC\/2012-related viruses in bats, Ghana and Europe","volume":"19","author":"Annan","year":"2013","journal-title":"Emerg. Infect. Dis."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.3201\/eid1911.131172","article-title":"Middle East respiratory syndrome coronavirus in Bats, Saudi Arabia","volume":"19","author":"Memish","year":"2013","journal-title":"Emerg. Infect. Dis."},{"key":"ref_52","first-page":"210","article-title":"Family Hipposideridae (Old World Leaf-nosed Bats)","volume":"9","author":"Monadjem","year":"2019","journal-title":"Handb. Mamm. World"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"20142124","DOI":"10.1098\/rspb.2014.2124","article-title":"Ecological dynamics of emerging bat virus spillover","volume":"282","author":"Plowright","year":"2014","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/zph.12000","article-title":"Ecology of Zoonotic Infectious Diseases in Bats: Current Knowledge and Future Directions","volume":"60","author":"Hayman","year":"2013","journal-title":"Zoonoses Public Health"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/mec.15250","article-title":"Demographic and environmental drivers of metagenomic viral diversity in vampire bats","volume":"29","author":"Bergner","year":"2020","journal-title":"Mol. Ecol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1038\/nm.3985","article-title":"A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence","volume":"21","author":"Menachery","year":"2015","journal-title":"Nat. Med."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nrmicro.2017.45","article-title":"Pathways to zoonotic spillover","volume":"15","author":"Plowright","year":"2017","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1128\/MMBR.00004-08","article-title":"Cross-Species Virus Transmission and the Emergence of New Epidemic Diseases","volume":"72","author":"Parrish","year":"2008","journal-title":"Microbiol. Mol. Biol. 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