{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:18:59Z","timestamp":1782973139324,"version":"3.54.5"},"reference-count":46,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T00:00:00Z","timestamp":1662163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Project funds of the Ministry of Health","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Project funds of the Ministry of Health","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"National Reference Centers of the Ministry of Health NRC IEV","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"National Reference Centers of the Ministry of Health NRC IEV","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"Public Health Authority of Slovak Republic, Bratislava","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Public Health Authority of Slovak Republic, Bratislava","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"Regional Public Health Authority, Banska Bystrica","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Regional Public Health Authority, Banska Bystrica","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"Regional Public Health Authority, Kosice","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Regional Public Health Authority, Kosice","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"Ministry of Health of the Slovak Republic","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Ministry of Health of the Slovak Republic","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]},{"name":"Operational Programme Integrated Infrastructure (OPII)","award":["MZSR 2016\/3-RUVZBB"],"award-info":[{"award-number":["MZSR 2016\/3-RUVZBB"]}]},{"name":"Operational Programme Integrated Infrastructure (OPII)","award":["ITMS 313011T721"],"award-info":[{"award-number":["ITMS 313011T721"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Enteroviruses (EVs) are associated with a wide spectrum of diseases involving various organs. Our aim was to give a historical overview of the genesis of clinical sample processing for EVs in the Slovak Republic (SR) during the 1958\u20132020 period, within the framework of the World Health Organization (WHO) polio program. Further, analyses were made of the data obtained from the archives of processed clinical sample surveillance using statistical methods. We used generalized additive models (GAM) with binomial distribution and logit link functions and an autoregressive moving average (ARMA) to analyze the data obtained during this 63-year period. Our results show trends in the composition of EV strains circulating in the population. Furthermore, statistically significant increasing trends of the non-polio enteroviruses (NPEVs) were observed over the studied time, represented by echoviruses (E) and coxsackieviruses A and B (CVA and CVB), with a cyclical pattern of occurrence. The most prevalent serotype over this period was CVB5, which became significantly more prevalent after 2000. While PVs, CVB1, and CVB3 were present in the second half of the studied period, CVA10, CVA16, E3, E25, and E30 appeared more frequently.<\/jats:p>","DOI":"10.3390\/v14091957","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T20:50:27Z","timestamp":1662670227000},"page":"1957","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surveillance Program of Clinical Samples for Polio and Non-Polio Enteroviruses in the Slovak Republic during the 1958\u20132020 Period"],"prefix":"10.3390","volume":"14","author":[{"given":"Renata","family":"Kissova","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Regional Public Health Authority Banska Bystrica, Cesta k Nemocnici 25, 97401 Banska Bystrica, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Pastuchova","sequence":"additional","affiliation":[{"name":"National Reference Laboratory of Poliomyelitis Public Health Authority, Trnavska Cesta, 82102 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viera","family":"Lengyelova","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Regional Public Health Authority Senny Trh, 82009 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2710-8102","authenticated-orcid":false,"given":"Marek","family":"Svitok","sequence":"additional","affiliation":[{"name":"Faculty of Ecology and Environmental Sciences, Technical University in Zvolen, T. G. Masaryka 24, 96001 Zvolen, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Mikas","sequence":"additional","affiliation":[{"name":"Public Health Authority, Trnavska Cesta, 82102 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8423-5565","authenticated-orcid":false,"given":"Shubhada","family":"Bopegamage","sequence":"additional","affiliation":[{"name":"Enterovirus Laboratory, Institute of Microbiology, Faculty of Medicine, Slovak Medical University, Limbova 12, 83303 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyril","family":"Klement","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Regional Public Health Authority Banska Bystrica, Cesta k Nemocnici 25, 97401 Banska Bystrica, Slovakia"},{"name":"Faculty of Public Health, Slovak Medical University, Limbova 12, 83303 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sioofy-Khojine, A.-B., Oikarinen, S., Honkanen, H., Huhtala, H., Lehtonen, J.P., Briese, T., and Hyoty, H. 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