{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:22:06Z","timestamp":1784917326878,"version":"3.55.0"},"reference-count":52,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T00:00:00Z","timestamp":1663372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ratchadaphiseksomphot Matching Fund","award":["RA-MF-11\/63"],"award-info":[{"award-number":["RA-MF-11\/63"]}]},{"name":"Ratchadaphiseksomphot Matching Fund","award":["CU_FRB640001_01_30_9"],"award-info":[{"award-number":["CU_FRB640001_01_30_9"]}]},{"name":"Thailand Science Research and Innovation Fund (TSRI)","award":["RA-MF-11\/63"],"award-info":[{"award-number":["RA-MF-11\/63"]}]},{"name":"Thailand Science Research and Innovation Fund (TSRI)","award":["CU_FRB640001_01_30_9"],"award-info":[{"award-number":["CU_FRB640001_01_30_9"]}]},{"name":"100th Anniversary Chulalongkorn University Fund","award":["RA-MF-11\/63"],"award-info":[{"award-number":["RA-MF-11\/63"]}]},{"name":"100th Anniversary Chulalongkorn University Fund","award":["CU_FRB640001_01_30_9"],"award-info":[{"award-number":["CU_FRB640001_01_30_9"]}]},{"name":"90th Anniversary Chulalongkorn University Fund","award":["RA-MF-11\/63"],"award-info":[{"award-number":["RA-MF-11\/63"]}]},{"name":"90th Anniversary Chulalongkorn University Fund","award":["CU_FRB640001_01_30_9"],"award-info":[{"award-number":["CU_FRB640001_01_30_9"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Although other co-viral infections could also be considered influencing factors, cervical human papillomavirus (HPV) infection is the main cause of cervical cancer. Metagenomics have been employed in the NGS era to study the microbial community in each habitat. Thus, in this investigation, virome capture sequencing was used to examine the virome composition in the HPV-infected cervix. Based on the amount of HPV present in each sample, the results revealed that the cervical virome of HPV-infected individuals could be split into two categories: HPV-dominated (HD; \u226560%) and non-HPV-dominated (NHD; &lt;60%). Cervical samples contained traces of several human viral species, including the molluscum contagiosum virus (MCV), human herpesvirus 4 (HHV4), torque teno virus (TTV), and influenza A virus. When compared to the HD group, the NHD group had a higher abundance of several viruses. Human viral diversity appears to be influenced by HPV dominance. This is the first proof that the diversity of human viruses in the cervix is impacted by HPV abundance. However, more research is required to determine whether human viral variety and the emergence of cancer are related.<\/jats:p>","DOI":"10.3390\/v14092066","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T00:08:09Z","timestamp":1663718889000},"page":"2066","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Human Virome in Cervix Controlled by the Domination of Human Papillomavirus"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7770-1097","authenticated-orcid":false,"given":"Thanayod","family":"Sasivimolrattana","sequence":"first","affiliation":[{"name":"Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand"},{"name":"Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wasun","family":"Chantratita","sequence":"additional","affiliation":[{"name":"Center for Medical Genomics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Insee","family":"Sensorn","sequence":"additional","affiliation":[{"name":"Center for Medical Genomics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1070-6747","authenticated-orcid":false,"given":"Arkom","family":"Chaiwongkot","sequence":"additional","affiliation":[{"name":"Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"},{"name":"Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3738-7061","authenticated-orcid":false,"given":"Shina","family":"Oranratanaphan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvapan","family":"Bhattarakosol","sequence":"additional","affiliation":[{"name":"Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"},{"name":"Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1386-6532(00)00125-6","article-title":"Human papillomavirus and cancer: The epidemiological evidence","volume":"19","author":"Munoz","year":"2000","journal-title":"J. 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