{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T21:33:01Z","timestamp":1773437581417,"version":"3.50.1"},"reference-count":50,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Council for Scientific and Technological Development: CNPq","award":["312446\/2018"],"award-info":[{"award-number":["312446\/2018"]}]},{"name":"National Council for Scientific and Technological Development: CNPq","award":["E-26\/203.064\/2016"],"award-info":[{"award-number":["E-26\/203.064\/2016"]}]},{"name":"National Council for Scientific and Technological Development: CNPq","award":["E-26\/202.431\/2019"],"award-info":[{"award-number":["E-26\/202.431\/2019"]}]},{"name":"National Council for Scientific and Technological Development: CNPq","award":["E-26\/201.335\/2016"],"award-info":[{"award-number":["E-26\/201.335\/2016"]}]},{"name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","award":["312446\/2018"],"award-info":[{"award-number":["312446\/2018"]}]},{"name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","award":["E-26\/203.064\/2016"],"award-info":[{"award-number":["E-26\/203.064\/2016"]}]},{"name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","award":["E-26\/202.431\/2019"],"award-info":[{"award-number":["E-26\/202.431\/2019"]}]},{"name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","award":["E-26\/201.335\/2016"],"award-info":[{"award-number":["E-26\/201.335\/2016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Beside humans, thousands of non-human primates (NHPs) died during the recent outbreak caused by the yellow fever virus (YFV) in Brazil. Vaccination of NHPs against YFV with the YF 17DD attenuated virus has emerged as a public health strategy, as it would reduce sylvatic transmission while also preserving endangered susceptible species. The hypothesis of establishing an uncontrolled transmission of this attenuated virus in nature was raised. We assessed vector competence of four sylvatic mosquito species, Haemagogus leucocelaenus, Haemagogus janthinomys\/capricornii, Sabethes albiprivus, and Sabethes identicus, as well as the urban vector Aedes aegypti for YF 17DD attenuated vaccine virus when fed directly on eleven viremic lion tamarins or artificially challenged with the same virus. No infection was detected in 689 mosquitoes engorged on viremic lion tamarins whose viremia ranged from 1.05 \u00d7 103 to 6.61 \u00d7 103 FFU\/mL, nor in those artificially taking \u2264 1 \u00d7 103 PFU\/mL. Low viremia presented by YF 17DD-vaccinated New World NHPs combined with the low capacity and null dissemination ability in sylvatic and domestic mosquitoes of this attenuated virus suggest no risk of its transmission in nature. Thus, vaccination of captive and free-living NHPs against YFV is a safe public health strategy.<\/jats:p>","DOI":"10.3390\/v14102231","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T02:10:27Z","timestamp":1665540627000},"page":"2231","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Neotropical Sylvatic Mosquitoes and Aedes aegypti Are Not Competent to Transmit 17DD Attenuated Yellow Fever Virus from Vaccinated Viremic New World Non-Human Primates"],"prefix":"10.3390","volume":"14","author":[{"given":"Rafaella Moraes","family":"de Miranda","sequence":"first","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5478-8233","authenticated-orcid":false,"given":"Rosilainy Surubi","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 Tavares","family":"da Silva-Fernandes","sequence":"additional","affiliation":[{"name":"Instituto de Tecnologia em Imunobiol\u00f3gicos\/Bio-Manguinhos, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anielly","family":"Ferreira-de-Brito","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Bahadian","family":"Moreira","sequence":"additional","affiliation":[{"name":"Centro de Primatologia do Rio de Janeiro\u2014CPRJ, Instituto Estadual do Ambiente, Guapimirim 25940-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Carvalho","family":"Pereira","sequence":"additional","affiliation":[{"name":"Instituto de Tecnologia em Imunobiol\u00f3gicos\/Bio-Manguinhos, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3493-105X","authenticated-orcid":false,"given":"Ygara","family":"da Silva Mendes","sequence":"additional","affiliation":[{"name":"Instituto de Tecnologia em Imunobiol\u00f3gicos\/Bio-Manguinhos, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9234-1678","authenticated-orcid":false,"given":"Sheila Maria Barbosa","family":"de Lima","sequence":"additional","affiliation":[{"name":"Instituto de Tecnologia em Imunobiol\u00f3gicos\/Bio-Manguinhos, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alcides","family":"Pissinatti","sequence":"additional","affiliation":[{"name":"Centro de Primatologia do Rio de Janeiro\u2014CPRJ, Instituto Estadual do Ambiente, Guapimirim 25940-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos da Silva","family":"Freire","sequence":"additional","affiliation":[{"name":"Instituto de Tecnologia em Imunobiol\u00f3gicos\/Bio-Manguinhos, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jer\u00f4nimo Augusto Fonseca","family":"Alencar","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0423-5694","authenticated-orcid":false,"given":"Ricardo","family":"Lourenco-de-Oliveira","sequence":"additional","affiliation":[{"name":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,11]]},"reference":[{"key":"ref_1","unstructured":"PAHO\u2014Pan American Health Organization (2022, July 30). 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