{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:26:43Z","timestamp":1760232403458,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council of Research Development","doi-asserted-by":"publisher","award":["CNPq\/Brazil, No. 431748\/2016-0"],"award-info":[{"award-number":["CNPq\/Brazil, No. 431748\/2016-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Background: Human T-cell lymphotropic virus type 1 (HTLV-1) infection can be associated with tropical spastic paraparesis (TSP\/HAM), which causes neurological myelopathy and sensory and muscle tone alterations, leading to gait and balance impairments. Once trunk perturbation is predicted, the motor control system uses anticipatory and compensatory mechanisms to maintain balance by recruiting postural muscles and displacement of the body\u2019s center of mass. Methods: Twenty-six participants (control or infected) had lower limb muscle onset and center of pressure (COP) displacements assessed prior to perturbation and throughout the entire movement. Results: Semitendinosus (ST) showed delayed onset in the infected group compared to the control group. The percentage of trials with detectable anticipatory postural adjustment was also lower in infected groups in the tibialis anterior and ST. In addition, COP displacement in the infected group was delayed, had a smaller amplitude, and took longer to reach the maximum displacement. Conclusions: HTLV-1 infected patients have less efficient anticipatory adjustments and greater difficulty recovering their postural control during the compensatory phase. Clinical assessment of this population should consider postural stability during rehabilitation programs.<\/jats:p>","DOI":"10.3390\/v14112389","type":"journal-article","created":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T10:47:57Z","timestamp":1667126877000},"page":"2389","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Postural Adjustments in HTLV-1 Infected Patients during a Self-Initiated Perturbation"],"prefix":"10.3390","volume":"14","author":[{"given":"Gizele Cristina Da Silva","family":"Almeida","sequence":"first","affiliation":[{"name":"Laboratory of Human Motricity Studies, Institute of Health Science, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"},{"name":"Tropical Medicine Institute, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lio Resque","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Laboratory of Human Motricity Studies, Institute of Health Science, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly Helorany Alves","family":"Costa","sequence":"additional","affiliation":[{"name":"Laboratory of Human Motricity Studies, Institute of Health Science, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"},{"name":"Tropical Medicine Institute, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex Tadeu Viana da Cruz","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Laboratory of Human Motricity Studies, Institute of Health Science, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"},{"name":"Tropical Medicine Institute, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela Rosa","family":"Garcez","sequence":"additional","affiliation":[{"name":"University Hospital Bettina Ferro de Souza, Federal University of Par\u00e1, Bel\u00e9m 66075-110, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4525-3971","authenticated-orcid":false,"given":"Givago da Silva","family":"Souza","sequence":"additional","affiliation":[{"name":"Tropical Medicine Institute, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"},{"name":"Neuroscience and Cell Biology Graduate Program (PPGNBC), Federal University of Par\u00e1, Bel\u00e9m 66075-110, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9151-3896","authenticated-orcid":false,"given":"Bianca","family":"Callegari","sequence":"additional","affiliation":[{"name":"Laboratory of Human Motricity Studies, Institute of Health Science, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"},{"name":"Tropical Medicine Institute, Federal University of Par\u00e1, Bel\u00e9m 66050-160, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s12038-018-9787-9","article-title":"HTLV-1: A real pathogen or a runaway guest of a diseased cell?","volume":"43","author":"Kanzaki","year":"2018","journal-title":"J. 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