{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:20:01Z","timestamp":1789604401620,"version":"build-2803163510"},"reference-count":93,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T00:00:00Z","timestamp":1674950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deutsche Forschungsgemeinschaft (DGF, German Research Foundation)"},{"name":"German, Austrian and Swiss Society of Thrombosis and Hemostasis Research (GTH)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>An increase in post-COVID patients with late sequelae of acute COVID-19 infection is emerging as an ongoing challenge for physicians and healthcare professionals. Since the beginning of the pandemic, it has rapidly become evident that the acute infection is not limited to the respiratory tract but that several organs, including the cardiovascular system, can be affected. Moreover, in a significant proportion of patients (ranging from about 10 to up to 50%) with former COVID-19, cardiopulmonary symptoms such as dyspnea, palpitations, restricted physical capacity, and cardiac arrhythmias can persist weeks and months after the acute SARS-CoV-2 infection. The spectrum of COVID-19-associated arrhythmias is rather wide, most likely due to various pathomechanisms. In this article, the prevalence of cardiac arrhythmias and underlying pathologies are reviewed, including direct myocardial injury and abnormal consequences with an impact on cardiac electric instability. The hyperinflammatory reaction of the host immune system is specifically considered. Moreover, several distinct rhythm disorders occurring in post-COVID patients are discussed with regard to their clinical management.<\/jats:p>","DOI":"10.3390\/v15020389","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T07:56:48Z","timestamp":1675065408000},"page":"389","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Cardiac Arrhythmias in Post-COVID Syndrome: Prevalence, Pathology, Diagnosis, and Treatment"],"prefix":"10.3390","volume":"15","author":[{"given":"Aydin","family":"Huseynov","sequence":"first","affiliation":[{"name":"Department of Medicine, Cardiology, Angiology, Hemostasis, and Intensive Care Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim, University of Heidelberg, DE 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Akin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiology, Angiology, Hemostasis, and Intensive Care Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim, University of Heidelberg, DE 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Duerschmied","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiology, Angiology, Hemostasis, and Intensive Care Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim, University of Heidelberg, DE 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fcdiger E.","family":"Scharf","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiology, Angiology, Hemostasis, and Intensive Care Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim, University of Heidelberg, DE 68167 Mannheim, Germany"},{"name":"Division of Experimental and Clinical Hemostasis, Hemotherapy, and Transfusion Medicine, and Hemophilia Comprehensive Care Center, Institute of Transplantation Diagnostics and Cell Therapy, Heinrich Heine University Medical Center, DE 40225 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/jama.2020.12603","article-title":"Persistent Symptoms in Patients After Acute COVID-19","volume":"324","author":"Carfi","year":"2020","journal-title":"JAMA"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1016\/j.jinf.2020.08.029","article-title":"Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19","volume":"81","author":"Garrigues","year":"2020","journal-title":"J. Infect."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1473-3099(20)30120-1","article-title":"An interactive web-based dashboard to track COVID-19 in real time","volume":"20","author":"Dong","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/s41591-020-0968-3","article-title":"Extrapulmonary manifestations of COVID-19","volume":"26","author":"Gupta","year":"2020","journal-title":"Nat. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0140-6736(20)32656-8","article-title":"6-month consequences of COVID-19 in patients discharged from hospital: A cohort study","volume":"397","author":"Huang","year":"2021","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41591-021-01283-z","article-title":"Post-acute COVID-19 syndrome","volume":"27","author":"Nalbandian","year":"2021","journal-title":"Nat. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"n136","DOI":"10.1136\/bmj.n136","article-title":"Managing the long term effects of covid-19: Summary of NICE, SIGN, and RCGP rapid guideline","volume":"372","author":"Shah","year":"2021","journal-title":"BMJ"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/eurheartj\/ehac031","article-title":"Long COVID: Post-acute sequelae of COVID-19 with a cardiovascular focus","volume":"43","author":"Raman","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Visco, V., Vitale, C., Rispoli, A., Izzo, C., Virtuoso, N., Ferruzzi, G.J., Santopietro, M., Melfi, A., Rusciano, M.R., and Maglio, A. (2022). Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems. J. Clin. Med., 11.","DOI":"10.3390\/jcm11030524"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S2213-2600(21)00383-0","article-title":"Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): A UK multicentre, prospective cohort study","volume":"9","author":"Evans","year":"2021","journal-title":"Lancet Respir. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1001\/jamacardio.2020.1096","article-title":"Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)","volume":"5","author":"Inciardi","year":"2020","journal-title":"JAMA Cardiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.amjms.2020.10.002","article-title":"Cardiac Involvement of COVID-19: A Comprehensive Review","volume":"361","author":"Chang","year":"2021","journal-title":"Am. J. Med. Sci."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s11936-022-00964-3","article-title":"COVID-19 and Cardiac Arrhythmias: A Contemporary Review","volume":"24","author":"Saha","year":"2022","journal-title":"Curr. Treat. Options Cardiovasc. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"117723","DOI":"10.1016\/j.lfs.2020.117723","article-title":"Myocardial injury and COVID-19: Possible mechanisms","volume":"253","author":"Gill","year":"2020","journal-title":"Life Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41577-022-00714-3","article-title":"Inflammatory cytokines and cardiac arrhythmias: The lesson from COVID-19","volume":"22","author":"Lazzerini","year":"2022","journal-title":"Nat. Rev. Immunol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Zhan, Y., Yue, H., Liang, W., and Wu, Z. (2022). Effects of COVID-19 on Arrhythmia. J. Cardiovasc. Dev. Dis., 9.","DOI":"10.3390\/jcdd9090292"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1080\/14779072.2021.1997589","article-title":"Cardiac arrhythmias associated with COVID-19 infection: State of the art review","volume":"19","author":"Mohammad","year":"2021","journal-title":"Expert Rev. Cardiovasc. Ther."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/s41591-021-01292-y","article-title":"Attributes and predictors of long COVID","volume":"27","author":"Sudre","year":"2021","journal-title":"Nat. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"101019","DOI":"10.1016\/j.eclinm.2021.101019","article-title":"Characterizing long COVID in an international cohort: 7 months of symptoms and their impact","volume":"38","author":"Davis","year":"2021","journal-title":"EClinicalMedicine"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1080\/23744235.2021.1924397","article-title":"Long COVID or post-COVID-19 syndrome: Putative pathophysiology, risk factors, and treatments","volume":"53","author":"Yong","year":"2021","journal-title":"Infect. Dis."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3528","DOI":"10.1038\/s41467-022-30836-0","article-title":"Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records","volume":"13","author":"Thompson","year":"2022","journal-title":"Nat. Commun."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0140-6736(20)32000-6","article-title":"Offline: COVID-19 is not a pandemic","volume":"396","author":"Horton","year":"2020","journal-title":"Lancet"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/S0140-6736(20)31130-2","article-title":"Offline: Don\u2019t let COVID-19 divert us completely","volume":"395","author":"Horton","year":"2020","journal-title":"Lancet"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"101062","DOI":"10.1016\/j.eclinm.2021.101062","article-title":"Obesity during COVID-19: An underrated pandemic?","volume":"39","author":"Grosso","year":"2021","journal-title":"EClinicalMedicine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1161\/01.RES.87.5.e1","article-title":"A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9","volume":"87","author":"Donoghue","year":"2000","journal-title":"Circ. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1093\/cvr\/cvaa078","article-title":"The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2","volume":"116","author":"Chen","year":"2020","journal-title":"Cardiovasc. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1161\/CIRCULATIONAHA.120.052824","article-title":"Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells","volume":"143","author":"McCracken","year":"2021","journal-title":"Circulation"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"e9610","DOI":"10.15252\/msb.20209610","article-title":"The protein expression profile of ACE2 in human tissues","volume":"16","author":"Hikmet","year":"2020","journal-title":"Mol. Syst. Biol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/infdis\/165.1.134","article-title":"An experimental model for myocarditis and congestive heart failure after rabbit coronavirus infection","volume":"165","author":"Edwards","year":"1992","journal-title":"J. Infect. Dis."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1093\/infdis\/166.5.978","article-title":"An experimental model for dilated cardiomyopathy after rabbit coronavirus infection","volume":"166","author":"Alexander","year":"1992","journal-title":"J. Infect. Dis."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jacbts.2021.01.002","article-title":"SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis","volume":"6","author":"Bailey","year":"2021","journal-title":"JACC Basic Transl. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1161\/CIRCRESAHA.121.317997","article-title":"COVID-19 and Cardiovascular Disease: From Bench to Bedside","volume":"128","author":"Chung","year":"2021","journal-title":"Circ. Res."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1093\/eurheartj\/ehaa664","article-title":"Pathological features of COVID-19-associated myocardial injury: A multicentre cardiovascular pathology study","volume":"41","author":"Basso","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ccep.2021.10.004","article-title":"COVID-19, Acute Myocardial Injury, and Infarction","volume":"14","author":"Conway","year":"2022","journal-title":"Card. Electrophysiol. Clin."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jacc.2020.11.031","article-title":"Pathological Evidence for SARS-CoV-2 as a Cause of Myocarditis: JACC Review Topic of the Week","volume":"77","author":"Kawakami","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.thromres.2020.05.032","article-title":"ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients","volume":"192","author":"Escher","year":"2020","journal-title":"Thromb. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1161\/ATVBAHA.122.317162","article-title":"Thromboinflammation: From Atherosclerosis to COVID-19","volume":"42","author":"Wagner","year":"2022","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1182\/bloodadvances.2021005949","article-title":"Inflammasome activation in neutrophils of patients with severe COVID-19","volume":"6","author":"Aymonnier","year":"2022","journal-title":"Blood Adv."},{"key":"ref_39","first-page":"138999","article-title":"Neutrophil extracellular traps in COVID-19","volume":"5","author":"Zuo","year":"2020","journal-title":"JCI Insight"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"15880","DOI":"10.1073\/pnas.1005743107","article-title":"Extracellular DNA traps promote thrombosis","volume":"107","author":"Fuchs","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.amjcard.2020.08.033","article-title":"Ventricular Fibrillation Storm in Coronavirus 2019","volume":"135","author":"Elsaid","year":"2020","journal-title":"Am. J. Cardiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3389\/fcvm.2020.00147","article-title":"Cardiac Injury and Clinical Course of Patients With Coronavirus Disease 2019","volume":"7","author":"Wang","year":"2020","journal-title":"Front. Cardiovasc. Med."},{"key":"ref_43","first-page":"1717","article-title":"Systemic inflammation and arrhythmic risk: Lessons from rheumatoid arthritis","volume":"38","author":"Lazzerini","year":"2017","journal-title":"Eur. Heart J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"a029348","DOI":"10.1101\/cshperspect.a029348","article-title":"Connexins and Disease","volume":"10","author":"Delmar","year":"2018","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/jamacardio.2019.0549","article-title":"Association of Influenza-like Illness Activity With Hospitalizations for Heart Failure: The Atherosclerosis Risk in Communities Study","volume":"4","author":"Kytomaa","year":"2019","journal-title":"JAMA Cardiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/s41577-018-0098-z","article-title":"Cardioimmunology of arrhythmias: The role of autoimmune and inflammatory cardiac channelopathies","volume":"19","author":"Lazzerini","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1161\/CIRCULATIONAHA.120.047293","article-title":"COVID-19, Arrhythmic Risk, and Inflammation: Mind the Gap!","volume":"142","author":"Lazzerini","year":"2020","journal-title":"Circulation"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jinf.2021.05.004","article-title":"Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review","volume":"83","author":"Korompoki","year":"2021","journal-title":"J. Infect."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/cvr\/cvaa324","article-title":"Cardiac fibrosis","volume":"117","author":"Frangogiannis","year":"2021","journal-title":"Cardiovasc. Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1016\/j.jcmg.2020.05.004","article-title":"Cardiac Involvement in Patients Recovered From COVID-2019 Identified Using Magnetic Resonance Imaging","volume":"13","author":"Huang","year":"2020","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1001\/jamacardio.2020.3557","article-title":"Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)","volume":"5","author":"Puntmann","year":"2020","journal-title":"JAMA Cardiol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jcmg.2016.01.033","article-title":"Myocardial Fibrosis Assessment by LGE Is a Powerful Predictor of Ventricular Tachyarrhythmias in Ischemic and Nonischemic LV Dysfunction: A Meta-Analysis","volume":"9","author":"Disertori","year":"2016","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.tcm.2017.01.011","article-title":"Myocardial fibrosis predicts ventricular tachyarrhythmias","volume":"27","author":"Disertori","year":"2017","journal-title":"Trends Cardiovasc. Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/eji.202048930","article-title":"Anti-heart antibodies levels and their correlation with clinical symptoms and outcomes in patients with confirmed or suspected diagnosis COVID-19","volume":"51","author":"Blagova","year":"2021","journal-title":"Eur. J. Immunol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41586-021-03631-y","article-title":"Diverse functional autoantibodies in patients with COVID-19","volume":"595","author":"Wang","year":"2021","journal-title":"Nature"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1016\/j.hrthm.2020.06.026","article-title":"COVID-19 cardiac injury: Implications for long-term surveillance and outcomes in survivors","volume":"17","author":"Mitrani","year":"2020","journal-title":"Heart Rhythm."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12026-021-09185-5","article-title":"Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: A case series of 20 patients","volume":"69","author":"Blitshteyn","year":"2021","journal-title":"Immunol. Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/joim.12852","article-title":"Postural orthostatic tachycardia syndrome: Clinical presentation, aetiology and management","volume":"285","author":"Fedorowski","year":"2019","journal-title":"J. Intern. Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0025-6196(11)61027-6","article-title":"Postural orthostatic tachycardia syndrome: The Mayo clinic experience","volume":"82","author":"Thieben","year":"2007","journal-title":"Mayo Clin. Proc."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.4065\/74.11.1106","article-title":"Postural tachycardia syndrome: Clinical features and follow-up study","volume":"74","author":"Sandroni","year":"1999","journal-title":"Mayo Clin. Proc."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1177\/0961203315587566","article-title":"Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS)","volume":"24","author":"Blitshteyn","year":"2015","journal-title":"Lupus"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1540-8167.2008.01407.x","article-title":"Postural tachycardia syndrome (POTS)","volume":"20","author":"Low","year":"2009","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.autneu.2018.02.005","article-title":"Postural tachycardia syndrome\u2014Diagnosis, physiology, and prognosis","volume":"215","author":"Arnold","year":"2018","journal-title":"Auton Neurosci."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.autneu.2018.03.004","article-title":"Cognitive and psychological issues in postural tachycardia syndrome","volume":"215","author":"Raj","year":"2018","journal-title":"Auton Neurosci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1016\/j.hrthm.2015.03.029","article-title":"2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope","volume":"12","author":"Sheldon","year":"2015","journal-title":"Heart Rhythm"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/s41598-021-03831-6","article-title":"Inappropriate sinus tachycardia in post-COVID-19 syndrome","volume":"12","author":"Aranyo","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10286-017-0452-4","article-title":"Infectious diseases causing autonomic dysfunction","volume":"28","year":"2018","journal-title":"Clin. Auton Res."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jacc.2018.12.064","article-title":"Autonomic Nervous System Dysfunction: JACC Focus Seminar","volume":"73","author":"Goldberger","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/j.amjmed.2021.07.004","article-title":"Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome","volume":"134","author":"Stahlberg","year":"2021","journal-title":"Am. J. Med."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ajem.2021.09.050","article-title":"Outcomes of atrial fibrillation in patients with COVID-19 pneumonia: A systematic review and meta-analysis","volume":"50","author":"Chen","year":"2021","journal-title":"Am. J. Emerg. Med."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.jacep.2021.02.009","article-title":"Atrial Fibrillation in Patients Hospitalized With COVID-19: Incidence, Predictors, Outcomes, and Comparison to Influenza","volume":"7","author":"Musikantow","year":"2021","journal-title":"JACC Clin. Electrophysiol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"e009375","DOI":"10.1161\/CIRCEP.120.009375","article-title":"Contribution of Atrial Fibrillation to In-Hospital Mortality in Patients With COVID-19","volume":"14","author":"Spinoni","year":"2021","journal-title":"Circ. Arrhythm Electrophysiol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.hrthm.2021.01.018","article-title":"Atrial fibrillation is an independent predictor for in-hospital mortality in patients admitted with SARS-CoV-2 infection","volume":"18","author":"Mountantonakis","year":"2021","journal-title":"Heart Rhythm"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jacbts.2020.04.002","article-title":"COVID-19 for the Cardiologist: Basic Virology, Epidemiology, Cardiac Manifestations, and Potential Therapeutic Strategies","volume":"5","author":"Atri","year":"2020","journal-title":"JACC Basic Transl. Sci."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/s41586-021-03553-9","article-title":"High-dimensional characterization of post-acute sequelae of COVID-19","volume":"594","author":"Xie","year":"2021","journal-title":"Nature"},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Diemberger, I., Vicentini, A., Cattafi, G., Ziacchi, M., Iacopino, S., Morani, G., Pisano, E., Molon, G., Giovannini, T., and Dello Russo, A. (2021). The Impact of COVID-19 Pandemic and Lockdown Restrictions on Cardiac Implantable Device Recipients with Remote Monitoring. J. Clin. Med., 10.","DOI":"10.3390\/jcm10235626"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"e023473","DOI":"10.1161\/JAHA.121.023473","article-title":"Cardiac Dysfunction and Arrhythmias 3 Months After Hospitalization for COVID-19","volume":"11","author":"Ingul","year":"2022","journal-title":"J. Am. Heart Assoc."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"4382","DOI":"10.1093\/eurheartj\/ehaa448","article-title":"Return to sports after COVID-19 infection","volume":"41","author":"Schellhorn","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"e001164","DOI":"10.1136\/bmjsem-2021-001164","article-title":"Cardiac abnormalities in athletes after SARS-CoV-2 infection: A systematic review","volume":"7","author":"Spies","year":"2021","journal-title":"BMJ Open Sport Exerc. Med."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1161\/CIRCULATIONAHA.121.054824","article-title":"SARS-CoV-2 Cardiac Involvement in Young Competitive Athletes","volume":"144","author":"Moulson","year":"2021","journal-title":"Circulation"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1136\/bjsports-2020-102789","article-title":"Is extensive cardiopulmonary screening useful in athletes with previous asymptomatic or mild SARS-CoV-2 infection?","volume":"55","author":"Gervasi","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ijcard.2021.05.042","article-title":"A prospective study on the consequences of SARS-CoV-2 infection on the heart of young adult competitive athletes: Implications for a safe return-to-play","volume":"336","author":"Cavigli","year":"2021","journal-title":"Int. J. Cardiol."},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Lamprinou, M., Sachinidis, A., Stamoula, E., Vavilis, T., and Papazisis, G. (2023). COVID-19 vaccines adverse events: Potential molecular mechanisms. Immunol. Res., 1\u201317.","DOI":"10.1007\/s12026-023-09357-5"},{"key":"ref_84","first-page":"103486","article-title":"Development of myocarditis and pericarditis after COVID-19 vaccination in children and adolescents: A systematic review","volume":"76","author":"Fatima","year":"2023","journal-title":"Clin. Cardiol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1161\/CIRCULATIONAHA.121.056135","article-title":"Myocarditis With COVID-19 mRNA Vaccines","volume":"144","author":"Bozkurt","year":"2021","journal-title":"Circulation"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"995167","DOI":"10.3389\/fped.2022.995167","article-title":"Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent","volume":"10","author":"Han","year":"2022","journal-title":"Front Pediatr."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10840-022-01263-4","article-title":"Atrial fibrillation after vaccination for COVID-19: Analysis of the vaccine adverse event reporting system","volume":"65","author":"Kumar","year":"2022","journal-title":"J. Interv. Card. Electrophysiol."},{"key":"ref_88","first-page":"627","article-title":"High degree atrio-ventricular block following COVID-19 vaccination","volume":"24","author":"Nashashibi","year":"2022","journal-title":"Isr. Med. Assoc. J."},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Chiu, S.N., Chen, Y.S., Hsu, C.C., Hua, Y.C., Tseng, W.C., Lu, C.W., Lin, M.T., Chen, C.A., Wu, M.H., and Chen, Y.T. (2023). Changes of ECG parameters after BNT162b2 vaccine in the senior high school students. Eur. J. Pediatr., 1\u20138.","DOI":"10.1007\/s00431-022-04786-0"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/s41591-021-01630-0","article-title":"Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection","volume":"28","author":"Patone","year":"2022","journal-title":"Nat. Med."},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Sangpornsuk, N., Rungpradubvong, V., Tokavanich, N., Srisomwong, S., Ananwattanasuk, T., Teerawongsakul, P., Kerr, S.J., Suwanwalaikorn, M., Jongnarangsin, K., and Chokesuwattanaskul, R. (2022). Arrhythmias after SARS-CoV-2 Vaccination in Patients with a Cardiac Implantable Electronic Device: A Multicenter Study. Biomedicines, 10.","DOI":"10.3390\/biomedicines10112838"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/j.hrthm.2018.04.007","article-title":"Fever-related arrhythmic events in the multicenter Survey on Arrhythmic Events in Brugada Syndrome","volume":"15","author":"Michowitz","year":"2018","journal-title":"Heart Rhythm"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1111\/jce.15596","article-title":"Fever following Covid-19 vaccination in subjects with Brugada syndrome: Incidence and management","volume":"33","author":"Santoro","year":"2022","journal-title":"J. Cardiovasc. Electrophysiol."}],"container-title":["Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-4915\/15\/2\/389\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:19:14Z","timestamp":1760120354000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-4915\/15\/2\/389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,29]]},"references-count":93,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["v15020389"],"URL":"https:\/\/doi.org\/10.3390\/v15020389","relation":{},"ISSN":["1999-4915"],"issn-type":[{"value":"1999-4915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,29]]}}}