{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:02:42Z","timestamp":1790701362065,"version":"4.1.0"},"reference-count":82,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["GHN-A-OO-09-00010-00"],"award-info":[{"award-number":["GHN-A-OO-09-00010-00"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["AID-OAA-A-14-00102"],"award-info":[{"award-number":["AID-OAA-A-14-00102"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["GHA-G-00-06-00001"],"award-info":[{"award-number":["GHA-G-00-06-00001"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["GHN-A-OO-09-00010-00"],"award-info":[{"award-number":["GHN-A-OO-09-00010-00"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["AID-OAA-A-14-00102"],"award-info":[{"award-number":["AID-OAA-A-14-00102"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["GHA-G-00-06-00001"],"award-info":[{"award-number":["GHA-G-00-06-00001"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>A One Health cross-sectoral surveillance approach was implemented to screen biological samples from bats, pigs, and humans at high-risk interfaces for zoonotic viral spillover for five viral families with zoonotic potential in Viet Nam. Over 1600 animal and human samples from bat guano harvesting sites, natural bat roosts, and pig farming operations were tested for coronaviruses (CoVs), paramyxoviruses, influenza viruses, filoviruses and flaviviruses using consensus PCR assays. Human samples were also tested using immunoassays to detect antibodies against eight virus groups. Significant viral diversity, including CoVs closely related to ancestors of pig pathogens, was detected in bats roosting at the human\u2013animal interfaces, illustrating the high risk for CoV spillover from bats to pigs in Viet Nam, where pig density is very high. Season and reproductive period were significantly associated with the detection of bat CoVs, with site-specific effects. Phylogeographic analysis indicated localized viral transmission among pig farms. Our limited human sampling did not detect any known zoonotic bat viruses in human communities living close to the bat cave and harvesting bat guano, but our serological assays showed possible previous exposure to Marburg virus-like (Filoviridae), Crimean\u2013Congo hemorrhagic fever virus-like (Bunyaviridae) viruses and flaviviruses. Targeted and coordinated One Health surveillance helped uncover this viral pathogen emergence hotspot.<\/jats:p>","DOI":"10.3390\/v15030790","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T07:06:37Z","timestamp":1679295997000},"page":"790","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["One Health Surveillance Highlights Circulation of Viruses with Zoonotic Potential in Bats, Pigs, and Humans in Viet Nam"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1249-2025","authenticated-orcid":false,"given":"Alice","family":"Latinne","sequence":"first","affiliation":[{"name":"Wildlife Conservation Society, Viet Nam Country Program, Hanoi 11111, Viet Nam"},{"name":"Wildlife Conservation Society, Health Program, Bronx, NY 10460, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thi Thanh","family":"Nga","sequence":"additional","affiliation":[{"name":"Wildlife Conservation Society, Viet Nam Country Program, Hanoi 11111, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Van","family":"Long","sequence":"additional","affiliation":[{"name":"Wildlife Conservation Society, Viet Nam Country Program, Hanoi 11111, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pham Thi Bich","family":"Ngoc","sequence":"additional","affiliation":[{"name":"Wildlife Conservation Society, Viet Nam Country Program, Hanoi 11111, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoang Bich","family":"Thuy","sequence":"additional","affiliation":[{"name":"Wildlife Conservation Society, Viet Nam Country Program, Hanoi 11111, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"PREDICT Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Van","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Ministry of Agricultural and Rural Development of Viet Nam, Hanoi 11519, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7093-7032","authenticated-orcid":false,"given":"Pham Thanh","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Ministry of Agricultural and Rural Development of Viet Nam, Hanoi 11519, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thanh","family":"Phuong","sequence":"additional","affiliation":[{"name":"Regional Animal Health Office No. 6, Ho Chi Minh City 72106, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Tin Vinh","family":"Quang","sequence":"additional","affiliation":[{"name":"Regional Animal Health Office No. 6, Ho Chi Minh City 72106, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Tung","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Ministry of Agricultural and Rural Development of Viet Nam, Hanoi 11519, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vu Sinh","family":"Nam","sequence":"additional","affiliation":[{"name":"National Institute of Hygiene and Epidemiology, Ministry of Health, Hanoi 11611, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vu Trong","family":"Duoc","sequence":"additional","affiliation":[{"name":"National Institute of Hygiene and Epidemiology, Ministry of Health, Hanoi 11611, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Duc","family":"Thinh","sequence":"additional","affiliation":[{"name":"National Institute of Hygiene and Epidemiology, Ministry of Health, Hanoi 11611, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randal","family":"Schoepp","sequence":"additional","affiliation":[{"name":"Diagnostic Systems Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keersten","family":"Ricks","sequence":"additional","affiliation":[{"name":"Diagnostic Systems Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Inui","sequence":"additional","affiliation":[{"name":"Food and Agriculture Organization of the United Nations (FAO), Country Office for Viet Nam, Hanoi 11112, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8861-0919","authenticated-orcid":false,"given":"Pawin","family":"Padungtod","sequence":"additional","affiliation":[{"name":"Food and 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