{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:12:52Z","timestamp":1790244772931,"version":"4.1.0"},"reference-count":62,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science and Higher Education of the Russian Federation","award":["075-15-2021-1355"],"award-info":[{"award-number":["075-15-2021-1355"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>The Zika virus (ZIKV) is a widespread mosquito-borne pathogen. Phylogenetically, two lineages of ZIKV are distinguished: African and Asian\u2013American. The latter became the cause of the 2015\u20132016 pandemic, with severe consequences for newborns. In West African countries, the African lineage was found, but there is evidence of the emergence of the Asian\u2013American lineage in Cape Verde and Angola. This highlights the need to not only monitor ZIKV but also sequence the isolates. In this article, we present a case report of Zika fever in a pregnant woman from Guinea identified in 2018. Viral RNA was detected through qRT-PCR in a serum sample. In addition, the seroconversion of anti-Zika IgM and IgG antibodies was detected in repeated blood samples. Subsequently, the virus was isolated from the C6\/36 cell line. The detected ZIKV belonged to the African lineage, the Nigerian sublineage. The strains with the closest sequences were isolated from mosquitoes in Senegal in 2011 and 2015. In addition, we conducted the serological screening of 116 blood samples collected from patients presenting to the hospital of Faranah with fevers during the period 2018\u20132021. As a result, it was found that IgM-positive patients were identified each year and that the seroprevalence varied between 5.6% and 17.1%.<\/jats:p>","DOI":"10.3390\/v15081620","type":"journal-article","created":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T00:45:02Z","timestamp":1690332302000},"page":"1620","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The First Case of Zika Virus Disease in Guinea: Description, Virus Isolation, Sequencing, and Seroprevalence in Local Population"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6460-0828","authenticated-orcid":false,"given":"Roman B.","family":"Bayandin","sequence":"first","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6835-4572","authenticated-orcid":false,"given":"Marat T.","family":"Makenov","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya St. 3A, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaba","family":"Boumbaly","sequence":"additional","affiliation":[{"name":"Virology Research Center\/Laboratory of Viral Hemorrhagic Fevers, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0741-3735","authenticated-orcid":false,"given":"Olga A.","family":"Stukolova","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya St. 3A, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7396-3954","authenticated-orcid":false,"given":"Anastasia V.","family":"Gladysheva","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey V.","family":"Shipovalov","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maksim O.","family":"Skarnovich","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousmane","family":"Camara","sequence":"additional","affiliation":[{"name":"H\u00f4pital R\u00e9gional de Faranah, Faranah, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aboubacar Hady","family":"Toure","sequence":"additional","affiliation":[{"name":"Research Institute of Applied Biology of Guinea, Pastoria, CREMS, Kindia, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor A.","family":"Svyatchenko","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander N.","family":"Shvalov","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir A.","family":"Ternovoi","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamadou Y.","family":"Boiro","sequence":"additional","affiliation":[{"name":"Research Institute of Applied Biology of Guinea, Pastoria, CREMS, Kindia, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander P.","family":"Agafonov","sequence":"additional","affiliation":[{"name":"State Research Center of Virology and Biotechnology \u00abVector\u00bb, 630559 Kol\u2019tsovo, Novosibirsk Oblast, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmila S.","family":"Karan","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya St. 3A, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0035-9203(82)90161-4","article-title":"Yellow Fever and Zika Virus Epizootics and Enzootics in Uganda","volume":"76","author":"McCrae","year":"1982","journal-title":"Trans. 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