{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:30:39Z","timestamp":1791959439423,"version":"4.3.4"},"reference-count":135,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T00:00:00Z","timestamp":1702080000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science and Technology of Colombia","award":["60845\u20132023"],"award-info":[{"award-number":["60845\u20132023"]}]},{"name":"Fondo de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n (FCTEI) del Sistema General de Regal\u00edas (SGR)","award":["60845\u20132023"],"award-info":[{"award-number":["60845\u20132023"]}]},{"name":"Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Sede Bogot\u00e1","award":["60845\u20132023"],"award-info":[{"award-number":["60845\u20132023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Parvoviruses (PVs) affect various animal species causing different diseases. To date, eight different porcine parvoviruses (PPV1 through PPV8) are recognized in the swine population, all of which are distributed among subfamilies and genera of the Parvoviridae family. PPV1 is the oldest and is recognized as the primary agent of SMEDI, while the rest of the PPVs (PPV2 through PPV8) are called novel PPVs (nPPVs). The pathogenesis of nPPVs is still undefined, and whether these viruses are putative disease agents is unknown. Structurally, the PPVs are very similar; the differences occur mainly at the level of their genomes (ssDNA), where there is variation in the number and location of the coding genes. Additionally, it is considered that the genome of PVs has mutation rates similar to those of ssRNA viruses, that is, in the order of 10\u22125\u201310\u22124 nucleotide\/substitution\/year. These mutations manifest mainly in the VP protein, constituting the viral capsid, affecting virulence, tropism, and viral antigenicity. For nPPVs, mutation rates have already been established that are similar to those already described; however, within this group of viruses, the highest mutation rate has been reported for PPV7. In addition to the mutations, recombinations are also reported, mainly in PPV2, PPV3, and PPV7; these have been found between strains of domestic pigs and wild boars and in a more significant proportion in VP sequences. Regarding affinity for cell types, nPPVs have been detected with variable prevalence in different types of organs and tissues; this has led to the suggestion that they have a broad tropism, although proportionally more have been found in lung and lymphoid tissue such as spleen, tonsils, and lymph nodes. Regarding their epidemiology, nPPVs are present on all continents (except PPV8, only in Asia), and within pig farms, the highest prevalences detecting viral genomes have been seen in the fattener and finishing groups. The relationship between nPPVs and clinical manifestations has been complicated to establish. However, there is already some evidence that establishes associations. One of them is PPV2 with porcine respiratory disease complex (PRDC), where causality tests (PCR, ISH, and histopathology) lead to proposing the PPV2 virus as a possible agent involved in this syndrome. With the other nPPVs, there is still no clear association with any pathology. These have been detected in different systems (respiratory, reproductive, gastrointestinal, urinary, and nervous), and there is still insufficient evidence to classify them as disease-causing agents. In this regard, nPPVs (except PPV8) have been found to cause porcine reproductive failure (PRF), with the most prevalent being PPV4, PPV6, and PPV7. In the case of PRDC, nPPVs have also been detected, with PPV2 having the highest viral loads in the lungs of affected pigs. Regarding coinfections, nPPVs have been detected in concurrence in healthy and sick pigs, with primary PRDC and PRF viruses such as PCV2, PCV3, and PRRSV. The effect of these coinfections is not apparent; it is unknown whether they favor the replication of the primary agents, the severity of the clinical manifestations, or have no effect. The most significant limitation in the study of nPPVs is that their isolation has been impossible; therefore, there are no studies on their pathogenesis both in vitro and in vivo. For all of the above, it is necessary to propose basic and applied research on nPPVs to establish if they are putative disease agents, establish their effect on coinfections, and measure their impact on swine production.<\/jats:p>","DOI":"10.3390\/v15122398","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T06:56:00Z","timestamp":1702277760000},"page":"2398","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["The Novel Porcine Parvoviruses: Current State of Knowledge and Their Possible Implications in Clinical Syndromes in Pigs"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-1759","authenticated-orcid":false,"given":"Diana S.","family":"Vargas-Bermudez","sequence":"first","affiliation":[{"name":"Universidad Nacional de Colombia, Sede Bogot\u00e1, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigaci\u00f3n en Infectolog\u00eda e Inmunolog\u00eda Veterinaria (CI3V), Carrera 30 No. 45-03, Bogot\u00e1 111321, CP, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Dario","family":"Mogollon","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia, Sede Bogot\u00e1, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigaci\u00f3n en Infectolog\u00eda e Inmunolog\u00eda Veterinaria (CI3V), Carrera 30 No. 45-03, Bogot\u00e1 111321, CP, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Franco-Rodriguez","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia, Sede Bogot\u00e1, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigaci\u00f3n en Infectolog\u00eda e Inmunolog\u00eda Veterinaria (CI3V), Carrera 30 No. 45-03, Bogot\u00e1 111321, CP, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7697-5101","authenticated-orcid":false,"given":"Jairo","family":"Jaime","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia, Sede Bogot\u00e1, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigaci\u00f3n en Infectolog\u00eda e Inmunolog\u00eda Veterinaria (CI3V), Carrera 30 No. 45-03, Bogot\u00e1 111321, CP, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1007\/s00705-020-04632-4","article-title":"Reorganizing the family Parvoviridae: A revised taxonomy independent of the canonical approach based on host association","volume":"165","author":"Canuti","year":"2020","journal-title":"Arch. Virol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1099\/jgv.0.001212","article-title":"Ictv Report Consortium ICTV virus taxonomy profile: Parvoviridae","volume":"100","author":"Cotmore","year":"2019","journal-title":"J. Gen. Virol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s12985-021-01677-y","article-title":"Small but mighty: Old and new parvoviruses of veterinary significance","volume":"18","author":"Jager","year":"2021","journal-title":"Virol. J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0378-4320(00)00135-4","article-title":"The effect of porcine parvovirus and porcine reproductive and respiratory syndrome virus on porcine reproductive performance","volume":"60\u201361","author":"Mengeling","year":"2000","journal-title":"Anim. Reprod. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.cvsm.2020.07.008","article-title":"Update on canine parvoviral enteritis","volume":"50","author":"Mazzaferro","year":"2020","journal-title":"Vet. Clin. N. Am. Small Anim. Pract."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.tvjl.2014.05.027","article-title":"Feline parvovirus infection and associated diseases","volume":"201","author":"Stuetzer","year":"2014","journal-title":"Vet. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/infdis\/152.2.257","article-title":"Experimental parvoviral infection in humans","volume":"152","author":"Anderson","year":"1985","journal-title":"J. Infect. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1111\/evj.13477","article-title":"Equine parvovirus hepatitis","volume":"53","author":"Ramsauer","year":"2021","journal-title":"Equine Vet. J."},{"key":"ref_9","first-page":"67","article-title":"Cloning of a human parvovirus by molecular screening of respiratory tract samples","volume":"10","author":"Ingrand","year":"2006","journal-title":"Virologie."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1099\/vir.0.2008\/000380-0","article-title":"Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4","volume":"89","author":"Lau","year":"2008","journal-title":"J. Gen. Virol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Xiao, C.-T., Gim\u00e9nez-Lirola, L.G., Jiang, Y.-H., Halbur, P.G., and Opriessnig, T. (2013). Characterization of a novel porcine parvovirus tentatively designated PPV5. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0065312"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s12985-014-0203-2","article-title":"Identification and genomic characterization of a novel porcine parvovirus (PPV6) in China","volume":"11","author":"Ni","year":"2014","journal-title":"Virol. J."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.vetmic.2014.06.024","article-title":"Identification of recently described porcine parvoviruses in archived North American samples from 1996 and association with porcine circovirus associated disease","volume":"173","author":"Opriessnig","year":"2014","journal-title":"Vet. Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1007\/s11262-016-1322-1","article-title":"Discovery of a novel Parvovirinae virus, porcine parvovirus 7, by metagenomic sequencing of porcine rectal swabs","volume":"52","author":"Palinski","year":"2016","journal-title":"Virus Genes"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1009103","DOI":"10.3389\/fvets.2022.1009103","article-title":"Identification and genomic characterization of a novel porcine parvovirus in China","volume":"9","author":"Guo","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.21775\/cimb.037.033","article-title":"Porcine Parvovirus","volume":"37","author":"Streck","year":"2020","journal-title":"Curr. Issues Mol. Biol."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Novosel, D., Cadar, D., Tuboly, T., Jungic, A., Stadejek, T., Ait-Ali, T., and Cs\u00e1gola, A. (2018). Investigating porcine parvoviruses genogroup 2 infection using in situ polymerase chain reaction. BMC Vet. Res., 14.","DOI":"10.1186\/s12917-018-1487-z"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"726884","DOI":"10.3389\/fvets.2021.726884","article-title":"Porcine parvovirus 2 is predominantly associated with macrophages in porcine respiratory disease complex","volume":"8","author":"Nelsen","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.meegid.2013.03.006","article-title":"Detection of novel porcine bocaviruses in fecal samples of asymptomatic pigs in Cameroon","volume":"17","author":"Ndze","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"ref_20","first-page":"642","article-title":"Rheumatologic manifestations of parvovirus B19 infection","volume":"82","author":"Chaabouni","year":"2004","journal-title":"Tunis. Med."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Mietzsch, M., P\u00e9nzes, J.J., and Agbandje-McKenna, M. (2019). Twenty-Five Years of Structural Parvovirology. Viruses, 11.","DOI":"10.3390\/v11040362"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Li, J., Xiao, Y., Qiu, M., Li, X., Li, S., Lin, H., Li, X., Zhu, J., and Chen, N. (2021). A Systematic Investigation Unveils High Coinfection Status of Porcine Parvovirus Types 1 through 7 in China from 2016 to 2020. Microbiol. Spectr., 9.","DOI":"10.1128\/Spectrum.01294-21"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.rvsc.2018.08.004","article-title":"The detection and genetic diversity of novel porcine parvovirus 7 (PPV7) on Polish pig farms","volume":"120","author":"Stadejek","year":"2018","journal-title":"Res. Vet. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1111\/tbed.13846","article-title":"Co-infection status of novel parvovirus\u2019s (PPV2 to 4) with porcine circovirus 2 in porcine respiratory disease complex and porcine circovirus-associated disease from 1997 to 2012","volume":"68","author":"Staines","year":"2021","journal-title":"Transbound. Emerg. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ympev.2012.09.030","article-title":"Capsid protein evolution and comparative phylogeny of novel porcine parvoviruses","volume":"66","author":"Cadar","year":"2013","journal-title":"Mol. Phylogenet. Evol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev-virology-031413-085444","article-title":"Parvoviruses: Small does not mean simple","volume":"1","author":"Cotmore","year":"2014","journal-title":"Annu. Rev. Virol."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"P\u00e9nzes, J.J., de Souza, W.M., Agbandje-McKenna, M., and Gifford, R.J. (2019). An Ancient Lineage of Highly Divergent Parvoviruses Infects both Vertebrate and Invertebrate Hosts. Viruses, 11.","DOI":"10.1101\/571109"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: Molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"8762","DOI":"10.1128\/JVI.73.10.8762-8770.1999","article-title":"Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19","volume":"73","author":"Sol","year":"1999","journal-title":"J. Virol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.1128\/JVI.76.7.3257-3266.2002","article-title":"Interaction between parvovirus NS2 protein and nuclear export factor Crm1 is important for viral egress from the nucleus of murine cells","volume":"76","author":"Miller","year":"2002","journal-title":"J. Virol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.vetmic.2012.11.032","article-title":"Interferon induction and suppression in swine testicle cells by porcine parvovirus and its proteins","volume":"163","author":"Lin","year":"2013","journal-title":"Vet. Microbiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1534-5807(01)00031-4","article-title":"A viral phospholipase A2 is required for parvovirus infectivity","volume":"1","author":"Szelei","year":"2001","journal-title":"Dev. Cell"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s00705-010-0646-8","article-title":"Identification and molecular cloning of a novel porcine parvovirus","volume":"155","author":"Cheung","year":"2010","journal-title":"Arch. Virol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"13129","DOI":"10.1128\/JVI.79.20.13129-13138.2005","article-title":"SAT: A late NS protein of porcine parvovirus","volume":"79","author":"Szelei","year":"2005","journal-title":"J. Virol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1159\/000173734","article-title":"Animal bocaviruses: A brief review","volume":"51","author":"Manteufel","year":"2008","journal-title":"Intervirology"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1006\/viro.1993.1569","article-title":"Genomic organization and mapping of transcription and translation products of the NADL-2 strain of porcine parvovirus","volume":"197","author":"Bergeron","year":"1993","journal-title":"Virology"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e01627-15","DOI":"10.1128\/genomeA.01627-15","article-title":"Complete Genome Sequence of Porcine Parvovirus 2 Recovered from Swine Sera","volume":"4","author":"Campos","year":"2016","journal-title":"Genome Announc."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e00021-12","DOI":"10.1128\/genomeA.00021-12","article-title":"Complete genome sequence of a novel porcine parvovirus (PPV) provisionally designated PPV5","volume":"1","author":"Xiao","year":"2013","journal-title":"Genome Announc."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Chung, H.-C., Nguyen, V.-G., Huynh, T.-M.-L., Park, Y.-H., Park, K.-T., and Park, B.-K. (2020). PCR-based detection and genetic characterization of porcine parvoviruses in South Korea in 2018. BMC Vet. Res., 16.","DOI":"10.1186\/s12917-020-02329-z"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.virol.2011.09.033","article-title":"Molecular characterization of the newly identified human parvovirus 4 in the family Parvoviridae","volume":"422","author":"Lou","year":"2012","journal-title":"Virology"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1128\/jvi.70.4.2508-2515.1996","article-title":"Genome organization of the Kresse strain of porcine parvovirus: Identification of the allotropic determinant and comparison with those of NADL-2 and field isolates","volume":"70","author":"Bergeron","year":"1996","journal-title":"J. Virol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1006\/jmbi.2001.5319","article-title":"The structure of porcine parvovirus: Comparison with related viruses","volume":"315","author":"Simpson","year":"2002","journal-title":"J. Mol. Biol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1006\/viro.1993.1288","article-title":"Structure, sequence, and function correlations among parvoviruses","volume":"194","author":"Chapman","year":"1993","journal-title":"Virology"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1073\/pnas.0406765102","article-title":"High rate of viral evolution associated with the emergence of carnivore parvovirus","volume":"102","author":"Shackelton","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/263106a0","article-title":"Rolling hairpin model for replication of parvovirus and linear chromosomal DNA","volume":"263","author":"Tattersall","year":"1976","journal-title":"Nature"},{"key":"ref_46","first-page":"349","article-title":"Parvovirus variation for disease: A difference with RNA viruses?","volume":"299","author":"Villarreal","year":"2006","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nrg2323","article-title":"Rates of evolutionary change in viruses: Patterns and determinants","volume":"9","author":"Duffy","year":"2008","journal-title":"Nat. Rev. Genet."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.meegid.2012.04.020","article-title":"Phylogeny and evolutionary genetics of porcine parvovirus in wild boars","volume":"12","author":"Cadar","year":"2012","journal-title":"Infect. Genet. Evol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1099\/vir.0.033662-0","article-title":"High rate of viral evolution in the capsid protein of porcine parvovirus","volume":"92","author":"Streck","year":"2011","journal-title":"J. Gen. Virol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1099\/vir.0.81086-0","article-title":"VP1 sequences of German porcine parvovirus isolates define two genetic lineages","volume":"87","author":"Zimmermann","year":"2006","journal-title":"J. Gen. Virol."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Oh, W.-T., Kim, R.-Y., Nguyen, V.-G., Chung, H.-C., and Park, B.-K. (2017). Perspectives on the evolution of porcine parvovirus. Viruses, 9.","DOI":"10.3390\/v9080196"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"veac053","DOI":"10.1093\/ve\/veac053","article-title":"Molecular epidemiology of Porcine Parvovirus Type 1 (PPV1) and the reactivity of vaccine-induced antisera against historical and current PPV1 strains","volume":"8","author":"Vereecke","year":"2022","journal-title":"Virus Evol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.meegid.2015.10.007","article-title":"Molecular epidemiology and evolution of porcine parvoviruses","volume":"36","author":"Streck","year":"2015","journal-title":"Infect. Genet. Evol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1099\/vir.0.82302-0","article-title":"Study of the virulence and cross-neutralization capability of recent porcine parvovirus field isolates and vaccine viruses in experimentally infected pregnant gilts","volume":"88","author":"Zeeuw","year":"2007","journal-title":"J. Gen. Virol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1099\/vir.0.055129-0","article-title":"Emerging novel porcine parvoviruses in Europe: Origin, evolution, phylodynamics and phylogeography","volume":"94","author":"Cadar","year":"2013","journal-title":"J. Gen. Virol."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Wang, D., Mai, J., Yang, Y., and Wang, N. (2020). Porcine Parvovirus 7: Evolutionary Dynamics and Identification of Epitopes toward Vaccine Design. Vaccines, 8.","DOI":"10.3390\/vaccines8030359"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/1348-0421.12159","article-title":"Coexistence of multiple strains of porcine parvovirus 2 in pig farms","volume":"58","author":"Saekhow","year":"2014","journal-title":"Microbiol. Immunol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s00705-015-2373-7","article-title":"Prevalence of emerging porcine parvoviruses and their co-infections with porcine circovirus type 2 in China","volume":"160","author":"Sun","year":"2015","journal-title":"Arch. Virol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1556\/004.2019.015","article-title":"First identification of porcine parvovirus 3 in a wild boar in Italy by viral metagenomics\u2014Short communication","volume":"67","author":"Amoroso","year":"2019","journal-title":"Acta Vet. Hung."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Kim, S.-C., Kim, J.-H., Kim, J.-Y., Park, G.-S., Jeong, C.-G., and Kim, W.-I. (2022). Prevalence of porcine parvovirus 1 through 7 (PPV1-PPV7) and co-factor association with PCV2 and PRRSV in Korea. BMC Vet. Res., 18.","DOI":"10.1186\/s12917-022-03236-1"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s11262-016-1386-y","article-title":"First identification of porcine parvovirus 6 in Poland","volume":"53","author":"Cui","year":"2017","journal-title":"Virus Genes"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Vargas-Bermudez, D.S., Rendon-Marin, S., Ruiz-Saenz, J., Mogoll\u00f3n, D., and Jaime, J. (2021). The first report of porcine parvovirus 7 (PPV7) in Colombia demonstrates the presence of variants associated with modifications at the level of the VP2-capsid protein. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0258311"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"949764","DOI":"10.3389\/fvets.2022.949764","article-title":"Genetic and epidemic characteristics of porcine parvovirus 7 in the Fujian and Guangdong regions of southern China","volume":"9","author":"Zhang","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"3294","DOI":"10.1099\/vir.0.83255-0","article-title":"Comparative analysis reveals frequent recombination in the parvoviruses","volume":"88","author":"Shackelton","year":"2007","journal-title":"J. Gen. Virol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1099\/vir.0.82496-0","article-title":"Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes","volume":"88","author":"Parsyan","year":"2007","journal-title":"J. Gen. Virol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1007\/s00705-021-05106-x","article-title":"Genetic analysis of porcine parvoviruses detected in South Korean wild boars","volume":"166","author":"Park","year":"2021","journal-title":"Arch. Virol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1099\/vir.0.045765-0","article-title":"Interclade recombination in porcine parvovirus strains","volume":"93","author":"Leal","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_68","first-page":"399","article-title":"Further studies on the cultivation of swine plague virus in cell cultures with a cytopathogenic effect","volume":"199","author":"Mayr","year":"1966","journal-title":"Zentralbl. Bakteriol. Orig."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"M\u00e9sz\u00e1ros, I., Olasz, F., Cs\u00e1gola, A., Tijssen, P., and Z\u00e1dori, Z. (2017). Biology of Porcine Parvovirus (Ungulate parvovirus 1). Viruses, 9.","DOI":"10.3390\/v9120393"},{"key":"ref_70","first-page":"244","article-title":"Identification of new parvovirus DNA sequence in swine sera from Myanmar","volume":"54","author":"Hijikata","year":"2001","journal-title":"Jpn. J. Infect. Dis."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s11262-010-0506-3","article-title":"Novel parvovirus sublineage in the family of Parvoviridae","volume":"41","author":"Wang","year":"2010","journal-title":"Virus Genes"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"e01738-16","DOI":"10.1128\/genomeA.01738-16","article-title":"Complete Genome Sequences of Porcine Parvovirus 2 Isolated from Swine in the Republic of Korea","volume":"5","author":"Lee","year":"2017","journal-title":"Genome Announc."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1007\/s00705-012-1257-3","article-title":"Detection, prevalence and analysis of emerging porcine parvovirus infections","volume":"157","author":"Cadar","year":"2012","journal-title":"Arch. Virol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1007\/s00705-013-1603-0","article-title":"Analysis of porcine parvoviruses in tonsils and hearts from healthy pigs reveals high prevalence and genetic diversity in Germany","volume":"158","author":"Streck","year":"2013","journal-title":"Arch. Virol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.actatropica.2018.10.010","article-title":"Prevalence of porcine parvoviruses in some South African swine herds with background of porcine circovirus type 2 infection","volume":"190","author":"Afolabi","year":"2019","journal-title":"Acta Trop."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Bhatta, T.R., Chamings, A., and Alexandersen, S. (2021). Exploring the Cause of Diarrhoea and Poor Growth in 8-11-Week-Old Pigs from an Australian Pig Herd Using Metagenomic Sequencing. Viruses, 13.","DOI":"10.3390\/v13081608"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.vetmic.2012.07.038","article-title":"Characterization of porcine parvovirus type 2 (PPV2) which is highly prevalent in the USA","volume":"161","author":"Xiao","year":"2013","journal-title":"Vet. Microbiol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/1348-0421.12782","article-title":"A retrospective study of DNA prevalence of porcine parvoviruses in Mexico and its relationship with porcine circovirus associated disease","volume":"64","author":"Brown","year":"2020","journal-title":"Microbiol. Immunol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/1743-422X-7-171","article-title":"High prevalence of porcine Hokovirus in German wild boar populations","volume":"7","author":"Adlhoch","year":"2010","journal-title":"Virol. J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1111\/tbed.12593","article-title":"Circulation of Porcine Parvovirus Types 1 through 6 in Serum Samples Obtained from Six Commercial Polish Pig Farms","volume":"64","author":"Cui","year":"2017","journal-title":"Transbound. Emerg. Dis."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"703","DOI":"10.7589\/2015-01-005","article-title":"Characterization of porcine parvovirus type 3 and porcine circovirus type 2 in wild boars (Sus scrofa) in slovakia","volume":"51","author":"Sliz","year":"2015","journal-title":"J. Wildl. Dis."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1007\/s00705-013-1690-y","article-title":"Prevalence of porcine hokovirus and its co-infection with porcine circovirus 2 in China","volume":"158","author":"Li","year":"2013","journal-title":"Arch. Virol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.vetmic.2012.05.038","article-title":"Increasing porcine PARV4 prevalence with pig age in the U.S. pig population","volume":"160","author":"Xiao","year":"2012","journal-title":"Vet. Microbiol."},{"key":"ref_84","first-page":"787","article-title":"High-throughput sequencing revealed the presence of an unforeseen parvovirus species in Canadian swine: The porcine partetravirus","volume":"54","author":"Bellehumeur","year":"2013","journal-title":"Can. Vet. J."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.bjm.2016.01.025","article-title":"Phylogenetic characterization of the first Ungulate tetraparvovirus 2 detected in pigs in Brazil","volume":"47","author":"Souza","year":"2016","journal-title":"Braz. J. Microbiol"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s00705-015-2730-6","article-title":"Porcine hokovirus in wild boar in Portugal","volume":"161","author":"Miranda","year":"2016","journal-title":"Arch. Virol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.virusres.2009.09.006","article-title":"Detection of a novel porcine boca-like virus in the background of porcine circovirus type 2 induced postweaning multisystemic wasting syndrome","volume":"146","author":"Fossum","year":"2009","journal-title":"Virus Res."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1186\/1743-422X-7-333","article-title":"Detection of a novel porcine parvovirus, PPV4, in Chinese swine herds","volume":"7","author":"Huang","year":"2010","journal-title":"Virol. J."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/1743-422X-9-192","article-title":"Viral metagenomic analysis of bushpigs (Potamochoerus larvatus) in Uganda identifies novel variants of Porcine parvovirus 4 and Torque teno sus virus 1 and 2","volume":"9","author":"Masembe","year":"2012","journal-title":"Virol. J."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jviromet.2015.03.011","article-title":"A TaqMan-based real-time PCR for detection and quantification of porcine parvovirus 4","volume":"219","author":"Gava","year":"2015","journal-title":"J. Virol. Methods"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1007\/s00705-013-1948-4","article-title":"First complete genomic characterization of a porcine parvovirus 5 isolate from China","volume":"159","author":"Wu","year":"2014","journal-title":"Arch. Virol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.virol.2020.09.005","article-title":"A plate of viruses: Viral metagenomics of supermarket chicken, pork and beef from Brazil","volume":"552","author":"Cibulski","year":"2021","journal-title":"Virology"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12985-015-0401-6","article-title":"First identification of porcine parvovirus 6 in North America by viral metagenomic sequencing of serum from pigs infected with porcine reproductive and respiratory syndrome virus","volume":"12","author":"Schirtzinger","year":"2015","journal-title":"Virol. J."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1136\/vr.105125","article-title":"Exploratory metagenomic analyses of periweaning failure-to-thrive syndrome-affected pigs","volume":"184","author":"Franzo","year":"2019","journal-title":"Vet. Rec."},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Mi\u0142ek, D., Wo\u017aniak, A., Guzowska, M., and Stadejek, T. (2019). Detection Patterns of Porcine Parvovirus (PPV) and Novel Porcine Parvoviruses 2 through 6 (PPV2-PPV6) in Polish Swine Farms. Viruses, 11.","DOI":"10.3390\/v11050474"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s00705-017-3585-9","article-title":"First identification of porcine parvovirus 7 in China","volume":"163","author":"Xing","year":"2018","journal-title":"Arch. Virol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"13341","DOI":"10.1038\/s41598-018-31554-8","article-title":"Viral communities associated with porcine respiratory disease complex in intensive commercial farms in Sichuan province, China","volume":"8","author":"Qin","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_98","doi-asserted-by":"crossref","unstructured":"Kim, S.-C., Jeong, C.-G., Nazki, S., Lee, S.-I., Baek, Y.-C., Jung, Y.-J., and Kim, W.-I. (2021). Evaluation of a multiplex PCR method for the detection of porcine parvovirus types 1 through 7 using various field samples. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0245699"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"104203","DOI":"10.1016\/j.meegid.2020.104203","article-title":"Liver virome of healthy pigs reveals diverse small ssDNA viral genomes","volume":"81","author":"Budaszewski","year":"2020","journal-title":"Infect. Genet. Evol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"855","DOI":"10.4142\/jvs.2018.19.6.855","article-title":"First detection and genetic characterization of porcine parvovirus 7 from Korean domestic pig farms","volume":"19","author":"Ouh","year":"2018","journal-title":"J. Vet. Sci."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0378-1135(87)90125-8","article-title":"Pathogenicity of a skin isolate of porcine parvovirus in swine fetuses","volume":"15","author":"Choi","year":"1987","journal-title":"Vet. Microbiol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.virol.2014.08.025","article-title":"What is for dinner? Viral metagenomics of US store bought beef, pork, and chicken","volume":"468\u2013470","author":"Zhang","year":"2014","journal-title":"Virology"},{"key":"ref_103","first-page":"493","article-title":"Role of the rat in the transmission of porcine parvovirus","volume":"43","author":"Cutler","year":"1982","journal-title":"Am. J. Vet. Res."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s11262-019-01661-3","article-title":"A novel parvovirus, Roe deer copiparvovirus, identified in Ixodes ricinus ticks","volume":"55","author":"Linden","year":"2019","journal-title":"Virus Genes"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1207\/s15327906mbr0601_5","article-title":"Multivariate analysis of gang delinquency: III. age and physique of gangs and clubs","volume":"6","author":"Cartwright","year":"1971","journal-title":"Multivar. Behav. Res."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1751-0813.1976.tb09517.x","article-title":"A standardised haemagglutination inhibition test for porcine parvovirus antibody","volume":"52","author":"Joo","year":"1976","journal-title":"Aust. Vet. J."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Jeoung, H.-Y., Lim, S.-I., Kim, J.-J., Cho, Y.-Y., Kim, Y.K., Song, J.-Y., Hyun, B.-H., and An, D.-J. (2015). Serological prevalence of viral agents that induce reproductive failure in South Korean wild boar. BMC Vet. Res., 11.","DOI":"10.1186\/s12917-015-0396-7"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/1743-422X-7-353","article-title":"Detection of porcine parvovirus using a taqman-based real-time pcr with primers and probe designed for the NS1 gene","volume":"7","author":"Song","year":"2010","journal-title":"Virol. J."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jviromet.2015.03.003","article-title":"A TaqMan qPCR for quantitation of Ungulate protoparvovirus 1 validated in several matrices","volume":"218","author":"Streck","year":"2015","journal-title":"J. Virol. Methods"},{"key":"ref_110","doi-asserted-by":"crossref","unstructured":"Yu, H.-Q., Cai, X.-Q., Lin, Z.-X., Li, X.-L., Yue, Q.-Y., Li, R., and Zhu, X.-Q. (2015). Rapid and specific detection of porcine parvovirus using real-time PCR and high resolution melting (HRM) analysis. BMC Vet. Res., 11.","DOI":"10.1186\/s12917-015-0364-2"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jviromet.2009.02.005","article-title":"Rapid detection of porcine parvovirus DNA by sensitive loop-mediated isothermal amplification","volume":"158","author":"Chen","year":"2009","journal-title":"J. Virol. Methods"},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"He, Y., Chen, W., Fan, J., Fan, S., Ding, H., Chen, J., and Yi, L. (2021). Recombinase-Aided Amplification Coupled with Lateral Flow Dipstick for Efficient and Accurate Detection of Porcine Parvovirus. Life, 11.","DOI":"10.3390\/life11080762"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0021-9975(69)90053-X","article-title":"A small haemagglutinating porcine DNA virus. I. Isolation and properties","volume":"79","author":"Cartwright","year":"1969","journal-title":"J. Comp. Pathol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"11748","DOI":"10.1128\/JVI.01717-14","article-title":"Classic nuclear localization signals and a novel nuclear localization motif are required for nuclear transport of porcine parvovirus capsid proteins","volume":"88","author":"Boisvert","year":"2014","journal-title":"J. Virol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jviromet.2006.01.022","article-title":"A colorimetric assay for viral agents that produce cytopathic effects","volume":"135","author":"Heldt","year":"2006","journal-title":"J. Virol. Methods"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF01317841","article-title":"Observations on the pathogenesis of porcine parvovirus infection","volume":"51","author":"Joo","year":"1976","journal-title":"Arch. Virol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"695553","DOI":"10.3389\/fvets.2021.695553","article-title":"High Co-infection Status of Novel Porcine Parvovirus 7 With Porcine Circovirus 3 in Sows That Experienced Reproductive Failure","volume":"8","author":"Mai","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Cs\u00e1gola, A., Z\u00e1dori, Z., M\u00e9sz\u00e1ros, I., and Tuboly, T. (2016). Detection of porcine parvovirus 2 (ungulate tetraparvovirus 3) specific antibodies and examination of the serological profile of an infected swine herd. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0151036"},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Mi\u0142ek, D., Wo\u017aniak, A., Podg\u00f3rska, K., and Stadejek, T. (2020). Do porcine parvoviruses 1 through 7 (PPV1-PPV7) have an impact on porcine circovirus type 2 (PCV2) viremia in pigs?. Vet. Microbiol., 242.","DOI":"10.1016\/j.vetmic.2020.108613"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s00705-020-04928-5","article-title":"First investigation of the prevalence of parvoviruses in slaughterhouse pigs and genomic characterization of ungulate copiparvovirus 2 in Vietnam","volume":"166","author":"Thuy","year":"2021","journal-title":"Arch. Virol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/1348-0421.12218","article-title":"Prevalence and genomic characterization of porcine parvoviruses detected in Chiangmai area of Thailand in 2011","volume":"59","author":"Saekhow","year":"2015","journal-title":"Microbiol. Immunol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.vetmic.2012.12.019","article-title":"Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2","volume":"163","author":"Opriessnig","year":"2013","journal-title":"Vet. Microbiol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"100187","DOI":"10.1016\/j.vas.2021.100187","article-title":"First investigation on the presence of porcine parvovirus type 3 in domestic pig farms without reproductive failure in the Democratic Republic of Congo","volume":"13","author":"Bisimwa","year":"2021","journal-title":"Vet. Anim. Sci."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s11250-017-1279-7","article-title":"Ungulate copiparvovirus 2 in healthy and postweaning multisystemic wasting syndrome-affected pigs","volume":"49","author":"Cibulski","year":"2017","journal-title":"Trop. Anim. Health Prod."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"Komina, A., Anoyatbekova, A., Krasnikov, N., and Yuzhakov, A. (2023). Identification and in vitro characterization of a novel porcine parvovirus 6 in Russia. Vet. Res. Commun., 1\u20139.","DOI":"10.1007\/s11259-023-10226-7"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.meegid.2019.03.004","article-title":"Detection and molecular characterization of novel porcine parvovirus 7 in Anhui province from Central-Eastern China","volume":"71","author":"Wang","year":"2019","journal-title":"Infect. Genet. Evol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1590\/S0100-736X2007001000007","article-title":"Co-infection by porcine circovirus type 2 and porcine parvovirus in aborted fetuses and stillborn piglets in southern Brazil","volume":"27","author":"Pescador","year":"2007","journal-title":"Pesq. Vet. Bras."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0378-1135(85)90061-6","article-title":"Parvovirus infection in pigs with necrotic and vesicle-like lesions","volume":"10","author":"Kresse","year":"1985","journal-title":"Vet. Microbiol."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13567-020-00807-8","article-title":"Coinfections and their molecular consequences in the porcine respiratory tract","volume":"51","author":"Saade","year":"2020","journal-title":"Vet. Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.vetmic.2003.11.006","article-title":"Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus","volume":"98","author":"Opriessnig","year":"2004","journal-title":"Vet. Microbiol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1053\/jcpa.1998.0295","article-title":"Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus","volume":"121","author":"Allan","year":"1999","journal-title":"J. Comp. Pathol."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/jcpa.1999.0337","article-title":"Reproduction of lesions of postweaning multisystemic wasting syndrome by infection of conventional pigs with porcine circovirus type 2 alone or in combination with porcine parvovirus","volume":"122","author":"Kennedy","year":"2000","journal-title":"J. Comp. Pathol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s11250-009-9454-0","article-title":"Porcine parvovirus- and porcine circovirus 2-associated reproductive failure and neonatal mortality in crossbred Indian pigs","volume":"42","author":"Sharma","year":"2010","journal-title":"Trop. Anim. Health Prod."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/j.vaccine.2020.01.013","article-title":"Porcine circovirus type 2a or 2b based experimental vaccines provide protection against PCV2d\/porcine parvovirus 2 co-challenge","volume":"38","author":"Opriessnig","year":"2020","journal-title":"Vaccine"},{"key":"ref_135","doi-asserted-by":"crossref","unstructured":"Wang, W., Cao, L., Sun, W., Xin, J., Zheng, M., Tian, M., Lu, H., and Jin, N. (2019). Sequence and phylogenetic analysis of novel porcine parvovirus 7 isolates from pigs in Guangxi, China. 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