{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:59:24Z","timestamp":1774270764339,"version":"3.50.1"},"reference-count":129,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Innovative Research Groups of Hubei Province","award":["2023AFA038"],"award-info":[{"award-number":["2023AFA038"]}]},{"name":"Innovative Research Groups of Hubei Province","award":["82071058"],"award-info":[{"award-number":["82071058"]}]},{"name":"Innovative Research Groups of Hubei Province","award":["2021YFF0702303"],"award-info":[{"award-number":["2021YFF0702303"]}]},{"name":"National Natural Science Foundation of China","award":["2023AFA038"],"award-info":[{"award-number":["2023AFA038"]}]},{"name":"National Natural Science Foundation of China","award":["82071058"],"award-info":[{"award-number":["82071058"]}]},{"name":"National Natural Science Foundation of China","award":["2021YFF0702303"],"award-info":[{"award-number":["2021YFF0702303"]}]},{"name":"National Key Research and Development Program of China","award":["2023AFA038"],"award-info":[{"award-number":["2023AFA038"]}]},{"name":"National Key Research and Development Program of China","award":["82071058"],"award-info":[{"award-number":["82071058"]}]},{"name":"National Key Research and Development Program of China","award":["2021YFF0702303"],"award-info":[{"award-number":["2021YFF0702303"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Herpesvirus is a prevalent pathogen that primarily infects human epithelial cells and has the ability to reside in neurons. In the field of otolaryngology, herpesvirus infection primarily leads to hearing loss and vestibular neuritis and is considered the primary hypothesis regarding the pathogenesis of vestibular neuritis. In this review, we provide a summary of the effects of the herpes virus on cellular processes in both host cells and immune cells, with a focus on HSV-1 as illustrative examples.<\/jats:p>","DOI":"10.3390\/v16010012","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T11:24:33Z","timestamp":1703071473000},"page":"12","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis"],"prefix":"10.3390","volume":"16","author":[{"given":"Zhengdong","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaozhou","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjun","family":"Zong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1771-3715","authenticated-orcid":false,"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China"},{"name":"Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1750-3639.2001.tb00408.x","article-title":"Prevalence of HSV-1 LAT in human trigeminal, geniculate, and vestibular ganglia and its implication for cranial nerve syndromes","volume":"11","author":"Theil","year":"2001","journal-title":"Brain Pathol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/1531-8249(199909)46:3<416::AID-ANA20>3.0.CO;2-W","article-title":"Distribution of herpes simplex virus type 1 in human geniculate and vestibular ganglia: Implications for vestibular neuritis","volume":"46","author":"Arbusow","year":"1999","journal-title":"Ann. 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