{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:08:02Z","timestamp":1791284882103,"version":"4.1.0"},"reference-count":256,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:00:00Z","timestamp":1719619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Antimicrobial resistance poses a serious risk to contemporary healthcare since it reduces the number of bacterial illnesses that may be treated with antibiotics, particularly for patients with long-term conditions like cystic fibrosis (CF). People with a genetic predisposition to CF often have recurrent bacterial infections in their lungs due to a buildup of sticky mucus, necessitating long-term antibiotic treatment. Pseudomonas aeruginosa infections are a major cause of CF lung illness, and P. aeruginosa airway isolates are frequently resistant to many antibiotics. Bacteriophages (also known as phages), viruses that infect bacteria, are a viable substitute for antimicrobials to treat P. aeruginosa infections in individuals with CF. Here, we reviewed the utilization of P. aeruginosa bacteriophages both in vivo and in vitro, as well as in the treatment of illnesses and diseases, and the outcomes of the latter.<\/jats:p>","DOI":"10.3390\/v16071051","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T03:38:27Z","timestamp":1719805107000},"page":"1051","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Pseudomonas aeruginosa Bacteriophages and Their Clinical Applications"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7839-3406","authenticated-orcid":false,"given":"Elaheh","family":"Alipour-Khezri","sequence":"first","affiliation":[{"name":"Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz 51368, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8791-9260","authenticated-orcid":false,"given":"Mikael","family":"Skurnik","sequence":"additional","affiliation":[{"name":"Human Microbiome Research Program, and Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1087-0769","authenticated-orcid":false,"given":"Gholamreza","family":"Zarrini","sequence":"additional","affiliation":[{"name":"Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz 51368, Iran"},{"name":"Microbial Biotechnology Research Group, University of Tabriz, Tabriz 51368, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Liang, S., Qi, Y., Yu, H., Sun, W., Raza, S.H.A., Alkhorayef, N., Alkhalil, S.S., Salama, E.E.A., and Zhang, L. 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