{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:20:37Z","timestamp":1760145637473,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Otto per Mille della Chiesa Valdese, Italy","award":["Ref. OPM\/2018\/01274"],"award-info":[{"award-number":["Ref. OPM\/2018\/01274"]}]},{"name":"Associazione Nazionale per la Lotta contro l\u2019AIDS\u2014SEZIONE LOMBARDA (ANLAIDS), Italy","award":["Ref. OPM\/2018\/01274"],"award-info":[{"award-number":["Ref. OPM\/2018\/01274"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>The objective of this study was to analyze the epidemiological links of the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and HIV-HCV coinfections to less studied types of transmission in certain populations. We performed an observational, prospective study on 903 patients aged between 15\u201387 years who took part in the Open Test Project. They were divided in two subgroups: general population vs. individuals from prisons who were questioned about multiple risk factors. A chi-square independence test was used to establish correlations between risk factors and results of screening tests. Logistic regression was used to calculate the probability of a reactive screening test based on each independent risk factor and age. HIV was very strongly associated with unprotected sexual intercourse with HIV-positive partners (the strongest association), unprotected sexual intercourse with sex workers, newly diagnosed sexually transmitted diseases (STDs), intravenous drug users (IDUs) and sharing injecting materials. In the case of HCV reactive tests, very strong associations have been established with IDUs (the strongest association), unprotected sex with IDUs and sharing injecting materials. Our study indicates the need for implementing targeted public health programs, tailored to the local epidemiology that can ultimately lead to micro-elimination of hepatitis and HIV infections in this area.<\/jats:p>","DOI":"10.3390\/v16081279","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T05:19:38Z","timestamp":1723439978000},"page":"1279","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["HIV, HCV and HIV-HCV Coinfections in the General Population versus Inmates from Romania"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5954-3312","authenticated-orcid":false,"given":"Camelia","family":"Sultana","sequence":"first","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"\u201c\u0218tefan S. Nicolau\u201d Institute of Virology, 030304 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmine","family":"Falanga","sequence":"additional","affiliation":[{"name":"ANLAIDS, Sezione Lombarda, 20154 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5577-369X","authenticated-orcid":false,"given":"Gra\u021biana","family":"Chicin","sequence":"additional","affiliation":[{"name":"General Medicine Department, \u201cVasile Goldi\u0219\u201d Western University of Arad, 310045 Arad, Romania"},{"name":"National Institute of Public Health, 050463 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4577-8450","authenticated-orcid":false,"given":"Lauren\u021biu","family":"Ion","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, \u201cVictor Babe\u0219\u201d Clinical Hospital of Infectious and Tropical Diseases, 030303 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camelia","family":"Grancea","sequence":"additional","affiliation":[{"name":"\u201c\u0218tefan S. 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