{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T19:53:06Z","timestamp":1772135586990,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>We determined the dengue virus (DENV) serotypes and genotypes in archived serum samples that were collected during the 2014\u20132016 and 2021 dengue outbreaks in Dire Dawa City and the Somali region in Ethiopia. DENV serotype 1 (DENV-1) was predominant followed by DENV serotype 2 (DENV-2). Thirteen of the DENV-1 strains were assigned to Genotype-I, while the remaining two were found to be Genotype-III. All three DENV-2 strains were assigned the Cosmopolitan Genotype. The DENV strains responsible for the outbreaks are genetically closely related to the DENV strains that circulated in neighboring and Asian countries. The findings also showed continued local transmission of a monophyletic lineage and a co-circulation of DENV-1 and DENV-2 during the outbreaks. There is a need to strengthen DENV genomic surveillance capacity for the early detection of circulating serotypes, and prevent devastating consequences of future outbreaks due to the co-circulation of different serotypes.<\/jats:p>","DOI":"10.3390\/v16081334","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T03:07:38Z","timestamp":1724296058000},"page":"1334","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Predominance of Dengue Virus Serotype-1\/Genotype-I in Eastern and Southeastern Ethiopia"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7756-9110","authenticated-orcid":false,"given":"Mesfin Mengesha","family":"Tsegaye","sequence":"first","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"},{"name":"State Key Laboratory of Emerging Infectious Diseases, School of Public Health, The University of Hong Kong, Hong Kong SAR 999077, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6338-9824","authenticated-orcid":false,"given":"Adamu Tayachew","family":"Mekonnen","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6396-8024","authenticated-orcid":false,"given":"Daniel Tsega","family":"Gebretsion","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0696-3786","authenticated-orcid":false,"given":"Tesfaye","family":"Gelanew","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawit Hailu","family":"Alemayehu","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8693-6501","authenticated-orcid":false,"given":"Dessalegn Abeje","family":"Tefera","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamirayehu Seyoum","family":"Woldemichael","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethlehem Adnew","family":"Getaneh","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni Kidane","family":"Abera","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6117-1589","authenticated-orcid":false,"given":"Gadissa Gutema","family":"Jebessa","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asefa Konde","family":"Korkiso","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengistu Biru","family":"Tessema","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Admikew Agunie","family":"Asfaw","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1013-5904","authenticated-orcid":false,"given":"Yoseph Asrat","family":"Temre","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mesfin","family":"Wossen","sequence":"additional","affiliation":[{"name":"Public Health Emergency Management Center, Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5942-1534","authenticated-orcid":false,"given":"Anne","family":"Piantadosi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2711-0501","authenticated-orcid":false,"given":"Huachen","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Emerging Infectious Diseases, School of Public Health, The University of Hong Kong, Hong Kong SAR 999077, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alemseged","family":"Abdissa","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adane","family":"Mihret","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2862-0175","authenticated-orcid":false,"given":"Andargachew","family":"Mulu","sequence":"additional","affiliation":[{"name":"Viral Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa P.O. Box 1005, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/01.qco.0000244047.31135.fa","article-title":"Immunopathological mechanisms in dengue and dengue hemorrhagic fever","volume":"19","author":"Green","year":"2006","journal-title":"Curr. Opin. Infect. 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