{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:14:56Z","timestamp":1791335696519,"version":"4.3.1"},"reference-count":57,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>The Africa Centers for Disease Control and Prevention declared mpox a Public Health Emergency of Continental Security (PHECS) in Africa. African public health systems have moved to mobilize a response against a backdrop of inherent significant challenges. With this commentary, we discuss how lessons from past public health emergencies, particularly COVID-19 and Ebola outbreaks, have prepared the region for improved disease surveillance, rapid response strategies, and effective public health communication and how these lessons can be applied to the mpox response, emphasizing the importance of strong healthcare infrastructure, effective data sharing, community engagement, targeted interventions, and robust contact tracing. Additionally, addressing misinformation and building public trust are crucial for controlling the spread of any disease. By leveraging these strategies, African countries can enhance their response to mpox. This includes improving diagnostic capabilities, strengthening cross-border collaborations, and prioritizing vaccination campaigns where needed. Ultimately, by applying the hard-earned lessons from the COVID-19 pandemic and Ebola outbreak, the East Africa region can better address the challenges posed by mpox and safeguard public health.<\/jats:p>","DOI":"10.3390\/v16101578","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T04:29:26Z","timestamp":1728361766000},"page":"1578","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Mpox in East Africa: Learning from COVID-19 and Ebola to Strengthen Public Health Responses"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9348-0936","authenticated-orcid":false,"given":"Pierre","family":"Gashema","sequence":"first","affiliation":[{"name":"Department of Research, Repolicy Research Centre, Kigali P.O. Box 7584, Rwanda"},{"name":"Centre for Genomic Biology, INES Ruhengeri, Ruhengeri P.O. Box 155, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-2818","authenticated-orcid":false,"given":"Tumusime","family":"Musafiri","sequence":"additional","affiliation":[{"name":"Partners in Health, Kigali P.O. Box 3432, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4008-6286","authenticated-orcid":false,"given":"Felix","family":"Ndahimana","sequence":"additional","affiliation":[{"name":"Laboratory of Entomology, Wageningen University and Research, Droevendaalsesteeg 4, 6708 PB Wageningen, The Netherlands"},{"name":"College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 4285, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyppolyte","family":"Iradukunda","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 4285, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3527-0262","authenticated-orcid":false,"given":"Eric","family":"Saramba","sequence":"additional","affiliation":[{"name":"Department of Research, Repolicy Research Centre, Kigali P.O. Box 7584, Rwanda"},{"name":"College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 4285, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart T.","family":"Nyakatswau","sequence":"additional","affiliation":[{"name":"Research and Development Department, Wastinnova Pvt Ltd., 5\/39 Strachan St, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7813-6440","authenticated-orcid":false,"given":"Noel","family":"Gahamanyi","sequence":"additional","affiliation":[{"name":"Rwanda Biomedical Centre, Kigali P.O. Box 7162, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0236-7776","authenticated-orcid":false,"given":"Patrick Gad","family":"Iradukunda","sequence":"additional","affiliation":[{"name":"Department of Research, Repolicy Research Centre, Kigali P.O. Box 7584, Rwanda"},{"name":"Drugs Department, Rwanda Food and Drugs Authority, Kigali P.O. Box 1948, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9516-9508","authenticated-orcid":false,"given":"Ayman","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Faculty of Science, University of Basel, Petersplatz 1, Basel P.O. Box 4001, Switzerland"},{"name":"Institute of Endemic Diseases, University of Khartoum, Khartoum 11111, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9929-5739","authenticated-orcid":false,"given":"Tafadzwa","family":"Dzinamarira","sequence":"additional","affiliation":[{"name":"ICAP Columbia University, Lusaka, Zambia"},{"name":"School of Health Systems and Public Health, University of Pretoria, Pretoria 0002, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude Mambo","family":"Muvunyi","sequence":"additional","affiliation":[{"name":"Rwanda Biomedical Centre, Kigali P.O. Box 7162, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"ref_1","unstructured":"(2024, October 03). Mpox (Formerly Monkeypox): Pathogenesis, Prevention and Treatment|Signal Transduction and Targeted Therapy. 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