{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:48:43Z","timestamp":1791996523149,"version":"4.4.0"},"reference-count":38,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Background: Brazil has witnessed the co-circulation of dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV), with outbreaks exacerbated by environmental factors, social determinants, and poor sanitation. The recent re-emergence of Oropouche virus (OROV) has added complexity to vector control strategies, emphasizing the need for integrated approaches to curb arboviruses spread. We aimed to analyze temporal trends and spatial distributions with national scope of these emerging arboviruses. Methods: An ecological study using data from the Brazilian Notifiable Diseases Information System the period from 2023 to 2024 was undertaken. Temporal trends were evaluated using Joinpoint regression, while spatial analysis was conducted using Moran\u2019s I, and local indicators of spatial association. Results: Dengue fever cases increased by 322%, while Oropouche fever (OF) increased by 300%. The states of Amazonas and Esp\u00edrito Santo reported increases in OF cases. Moran\u2019s I test revealed spatial clustering of DENV and CHIKV. Two municipalities in the state of Mato Grosso do Sul showed cocirculation of DENV, CHIKV, and ZIKV. Conclusions: This study identified a surge in arbovirus cases between 2023 and 2024, with peak incidences from January to March and October to December, linked to favorable climatic conditions. Clustering patterns and co-circulation of arboviruses highlight the need for tailored control and prevention strategies and targeted interventions to mitigate their impact.<\/jats:p>","DOI":"10.3390\/v17020158","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T03:26:31Z","timestamp":1737689191000},"page":"158","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Rising Incidence and Spatiotemporal Dynamics of Emerging and Reemerging Arboviruses in Brazil"],"prefix":"10.3390","volume":"17","author":[{"given":"Matheus","family":"Daudt-Lemos","sequence":"first","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6037-8206","authenticated-orcid":false,"given":"Alice","family":"Ramos-Silva","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renan","family":"Faustino","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Laboratory of Respiratory Viruses, Exanthematics, Enteroviruses and Viral Emergencies, Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Rio de Janeiro 21040900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3323-4511","authenticated-orcid":false,"given":"Tatiana Guimar\u00e3es de","family":"Noronha","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Department of Paediatrics, University of Oxford, Oxford OX3 7LE, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6416-7278","authenticated-orcid":false,"given":"Renata Artimos de Oliveira","family":"Vianna","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1755-999X","authenticated-orcid":false,"given":"Mauro Jorge","family":"Cabral-Castro","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Graduate Program in Pathology, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7638-6814","authenticated-orcid":false,"given":"Claudete Aparecida Ara\u00fajo","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5856-6128","authenticated-orcid":false,"given":"Andrea Alice","family":"Silva","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Graduate Program in Pathology, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4713-233X","authenticated-orcid":false,"given":"Fabiana Rabe","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Multiuser Laboratory for Research Support in Nephrology and Medical Sciences, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, Brazil"},{"name":"Graduate Program in Pathology, Faculty of Medicine, Universidade Federal Fluminense, Niter\u00f3i 24033900, RJ, 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Health"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.actatropica.2019.01.020","article-title":"Simultaneous Circulation of Arboviruses and Other Congenital Infections in Pregnant Women in Rio de Janeiro, Brazil","volume":"192","author":"Carvalho","year":"2019","journal-title":"Acta Trop."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.coviro.2020.05.001","article-title":"Climate Change and Viral Emergence: Evidence from Aedes-borne Arboviruses","volume":"40","author":"Robert","year":"2020","journal-title":"Curr. Opin. Virol."},{"key":"ref_4","first-page":"15412","article-title":"Impact of SimultaneousExposuretoArbovirusesonInfectionandTransmissionby Aedes Aegypti Mosquitoes","volume":"8","author":"Young","year":"2017","journal-title":"Nat. Commun."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Scachetti, G.C., Forato, J., Claro, I.M., Hua, X., Salgado, B.B., Vieira, A., Simeoni, C.L., Barbosa, A.R.C., Rosa, I.L., and de Souza, G.F. (Lancet Infect. Dis., 2024). Re-Emergence of Oropouche Virus between 2023 and 2024 in Brazil: An Observational Epidemiological Study, Lancet Infect. Dis., online ahead of print.","DOI":"10.1016\/S1473-3099(24)00619-4"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"100904","DOI":"10.1016\/S2666-5247(24)00136-8","article-title":"Oropouche Fever Outbreak in Brazil: An Emerging Concern in Latin America","volume":"5","author":"Sah","year":"2024","journal-title":"Lancet Microbe"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"105155","DOI":"10.1016\/j.jcv.2022.105155","article-title":"Arbovirus Outbreak in a Rural Region of the Brazilian Amazon","volume":"150\u2013151","author":"Carvalho","year":"2022","journal-title":"J. Clin. Virol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Lim, A.-Y., Jafari, Y., Caldwell, J.M., Clapham, H.E., Gaythorpe, K.A.M., Hussain-Alkhateeb, L., Johansson, M.A., Kraemer, M.U.G., Maude, R.J., and McCormack, C.P. (2023). A Systematic Review of the Data, Methods and Environmental Covariates Used to Map Aedes-Borne Arbovirus Transmission Risk. BMC Infect. Dis., 23.","DOI":"10.1186\/s12879-023-08717-8"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Rodriguez-Morales, A.J., and Drexler, J.F. (2024). Re-Emergence of Oropouche Virus in Brazil and Latin America. Lancet Infect. Dis.","DOI":"10.1016\/S1473-3099(24)00672-8"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"106928","DOI":"10.1016\/j.actatropica.2023.106928","article-title":"Influence of Meteorological and Seasonal Parameters on the Activity of Culicoides Paraensis (Diptera: Ceratopogonidae), an Annoying Anthropophilic Biting Midge and Putative Vector of Oropouche Virus in Rond\u00f4nia, Brazilian Amazon","volume":"243","author":"Feitoza","year":"2023","journal-title":"Acta Trop."},{"key":"ref_11","unstructured":"Pan American Health Organization, W.H.O. (PAHO\/W) (2025, January 09). Epidemiological Update Oropouche in the Americas Region\u201415 October 2024\u2014PAHO\/WHO|Pan American Health Organization. Available online: https:\/\/www.paho.org\/en\/documents\/epidemiological-update-oropouche-americas-region-15-october-2024."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"164","DOI":"10.7883\/yoken.JJID.2019.296","article-title":"Oropouche Virus Detection in Febrile Patients\u2019 Saliva and Urine Samples in Salvador, Bahia, Brazil","volume":"73","author":"Fonseca","year":"2020","journal-title":"Jpn. J. Infect. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"101502","DOI":"10.1016\/j.berh.2020.101502","article-title":"Arboviruses Related with Chronic Musculoskeletal Symptoms","volume":"34","author":"Ranzolin","year":"2020","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Celone, M., Pecor, D.B., Potter, A., Richardson, A., Dunford, J., and Pollett, S. (2022). An Ecological Niche Model to Predict the Geographic Distribution of HaemagogusJanthinomys, Dyar, 1921 a Yellow Fever and Mayaro Virus Vector, in South America. PLoS Negl. Trop. Dis., 16.","DOI":"10.1371\/journal.pntd.0010564"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s40249-018-0473-9","article-title":"Effective Surveillance Systems for Vector-Borne Diseases in Urban Settings and Translation of the Data into Action: A Scoping Review","volume":"7","author":"Fournet","year":"2018","journal-title":"Infect. Dis. Poverty"},{"key":"ref_16","first-page":"e240017","article-title":"Spatial Distribution of Arboviruses and Its Association with a Social Development Index and the Waste Disposal in S\u00e3o Lu\u00eds, State of Maranh\u00e3o, Brazil, 2015 to 2019","volume":"27","author":"Pereira","year":"2024","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Olliaro, P., Fouque, F., Kroeger, A., Bowman, L., Velayudhan, R., Santelli, A.C., Garcia, D., Skewes Ramm, R., Sulaiman, L.H., and Tejeda, G.S. (2018). Improved Tools and Strategies for the Prevention and Control of Arboviral Diseases: A Research-to-Policy Forum. PLoS Negl. Trop. Dis., 12.","DOI":"10.1371\/journal.pntd.0005967"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3961\/jpmph.21.160","article-title":"A Systematic Review of Spatial and Spatio-Temporal Analyses in Public Health Research in Korea","volume":"54","author":"Byun","year":"2021","journal-title":"J. Prev. Med. Public Health"},{"key":"ref_19","first-page":"e220039","article-title":"Temporal and Spatial Analysis of Municipal Dengue Cases in Paran\u00e1 and Social and Environmental Indicators, 2012 to 2021: Ecological Study","volume":"25","author":"Leandro","year":"2022","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Gr\u00e4f, T., Delatorre, E., do Nascimento Ferreira, C., Rossi, A., Santos, H.G.G., Pizzato, B.R., Nascimento, V., Souza, V., de Lima, G.B., and Dezordi, F.Z. (2024). Expansion of Oropouche Virus in Non-Endemic Brazilian Regions: Analysis of Genomic Characterisation and Ecological Drivers. Lancet Infect. Dis.","DOI":"10.1016\/S1473-3099(24)00687-X"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Leandro, A.S., Chiba de Castro, W.A., Garey, M.V., and Maciel-de-Freitas, R. (2024). Spatial Analysis of Dengue Transmission in an Endemic City in Brazil Reveals High Spatial Structuring on Local Dengue Transmission Dynamics. Sci. Rep., 14.","DOI":"10.1038\/s41598-024-59537-y"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"101237","DOI":"10.1016\/j.cois.2024.101237","article-title":"Dynamics of Aedes Aegypti Mating Behaviour","volume":"65","author":"Triana","year":"2024","journal-title":"Curr. Opin. Insect Sci."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Queiroz, E.R.d.S., and Medronho, R.d.A. (2022). Overlap between dengue, Zika and chikungunya hotspots in the city of Rio de Janeiro. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0273980"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Churakov, M., Villabona-Arenas, C.J., Kraemer, M.U.G., Salje, H., and Cauchemez, S. (2019). Spatio-temporal dynamics of dengue in Brazil: Seasonal travelling waves and determinants of regional synchrony. PLoS Negl. Trop. Dis., 13.","DOI":"10.1371\/journal.pntd.0007012"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.meegid.2018.11.009","article-title":"Aedes Aegypti Vector Competence Studies: A Review","volume":"67","author":"Powell","year":"2019","journal-title":"Infect. Genet. Evol."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Smith, D.L., Battle, K.E., Hay, S.I., Barker, C.M., Scott, T.W., and McKenzie, F.E. (2012). Ross, Macdonald, and a Theory for the Dynamics and Control of Mosquito-Transmitted Pathogens. PLoS Pathog., 8.","DOI":"10.1371\/journal.ppat.1002588"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Velez, I.D., Tanamas, S.K., Arbelaez, M.P., Kutcher, S.C., Duque, S.L., Uribe, A., Zuluaga, L., Mart\u00ednez, L., Pati\u00f1o, A.C., and Barajas, J. (2023). Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study. PLoS Negl. Trop. Dis., 17.","DOI":"10.1371\/journal.pntd.0011713"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"taae014","DOI":"10.1093\/jtm\/taae014","article-title":"The Epidemiology of Imported and Locally Acquired Dengue in Australia, 2012\u20132022","volume":"31","author":"Sohail","year":"2024","journal-title":"J. Travel Med."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Ogunlade, S.T., Adekunle, A.I., Meehan, M.T., and McBryde, E.S. (2023). Quantifying the Impact of Wolbachia Releases on Dengue Infection in Townsville, Australia. Sci. Rep., 13.","DOI":"10.1038\/s41598-023-42336-2"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"S453","DOI":"10.1093\/infdis\/jiw285","article-title":"Invasiveness of Aedes Aegypti and Aedes Albopictus and Vectorial Capacity for Chikungunya Virus","volume":"214","author":"Lounibos","year":"2016","journal-title":"J. Infect. Dis."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1038\/s41591-024-03300-3","article-title":"Human Outbreaks of a Novel Reassortant Oropouche Virus in the Brazilian Amazon Region","volume":"30","author":"Naveca","year":"2024","journal-title":"Nat. Med."},{"key":"ref_32","unstructured":"(2025, January 09). Instituto Nacional de Metorologia SPI\u2014\u00cdndice de Precipita\u00e7\u00e3o Padronizada, Available online: https:\/\/portal.inmet.gov.br\/servicos\/spi-%C3%ADndice-de-precipita%C3%A7%C3%A3o-padronizada."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"e358","DOI":"10.1016\/S1473-3099(24)00310-4","article-title":"Brazil\u2019s Dengue Vaccine Campaign Falters","volume":"24","author":"Triunfol","year":"2024","journal-title":"Lancet Infect. Dis."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Diaz-Quijano, F.A., Carvalho, D.S.d., Raboni, S.M., Shimakura, S.E., Mello, A.M.d., Costa-Ribeiro, M.C.V.d., Silva, L., Buffon, M.d.C.M., Maluf, E.M.C.P., and Graeff, G. (2024). Effectiveness of Mass Dengue Vaccination with CYD-TDV (Dengvaxia\u00ae) in the State of Paran\u00e1, Brazil: Integrating Case-Cohort and Case-Control Designs. Lancet Reg. Health\u2013Am., 35.","DOI":"10.1016\/j.lana.2024.100777"},{"key":"ref_35","unstructured":"(2025, January 09). Instituto Butantam Vacina da Chikungunya Mant\u00e9m Prote\u00e7\u00e3o em 99.1% dos Vacinados Seis Meses Ap\u00f3s Aplica\u00e7\u00e3o, Available online: https:\/\/butantan.gov.br\/noticias\/vacina-da-chikungunya-mantem-protecao-em-991-dos-vacinados-seis-meses-apos-aplicacao."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2301573","DOI":"10.1080\/21505594.2023.2301573","article-title":"Ixchiq (VLA1553): The First FDA-Approved Vaccine to Prevent Disease Caused by Chikungunya Virus Infection","volume":"15","author":"Ly","year":"2024","journal-title":"Virulence"},{"key":"ref_37","first-page":"e2021903","article-title":"Burnout Syndrome and Job Satisfaction in Community Health Workers","volume":"21","author":"Menguer","year":"2024","journal-title":"Rev. Bras. Med. Trab."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4269\/ajtmh.22-0777","article-title":"Differential Susceptibility of Aedes Aegypti and Aedes Albopictus Mosquitoes to Infection by Mayaro Virus Strains","volume":"109","author":"Yun","year":"2023","journal-title":"Am. J. Trop. Med. Hyg."}],"container-title":["Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-4915\/17\/2\/158\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:35:06Z","timestamp":1759919706000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-4915\/17\/2\/158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,24]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["v17020158"],"URL":"https:\/\/doi.org\/10.3390\/v17020158","relation":{},"ISSN":["1999-4915"],"issn-type":[{"value":"1999-4915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,24]]}}}