{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:08:19Z","timestamp":1788476899776,"version":"build-2803163510"},"reference-count":33,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2023KY638"],"award-info":[{"award-number":["2023KY638"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>(1) Background: We aimed to analyze the epidemiological characteristics of hemorrhagic fever with renal syndrome (HFRS) in Longyou County and to provide a basis for the future response to this disease. (2) Methods: Data on hemorrhagic fever and host animals were collected from 2011 to 2023. Descriptive methods were used to analyze the epidemic. The R4.4.1 software was used to show how the host density relates to the virus levels, temperature, and rainfall and to predict the host density. (3) Results: We observed 58 cases of hemorrhagic fever, the majority of which occurred in farmers. There were two incidence peaks each year during the spring and winter seasons, accounting for 22.41% and 43.10% of the total cases, respectively. The outdoor rodent population density was significantly and positively correlated with the outdoor rodent virus prevalence (R2 = 0.9411), serving as a robust predictor of the outdoor rodent virus prevalence. Additionally, the density of outdoor rodents exhibited a strong nonlinear relationship with the temperature and precipitation. (4) Conclusions: After hemorrhagic fever vaccination, rodent population density control, and rodent carrier rodent control from 1995 to 2000, the hemorrhagic fever epidemic was generally stable, and the epidemiological characteristics remained stable. In the future, we should continue to take active and effective comprehensive measures to intervene, further realize the effective control of HFRS, and prevent the recurrence of hemorrhagic fever epidemics.<\/jats:p>","DOI":"10.3390\/v17030313","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T03:40:12Z","timestamp":1740454812000},"page":"313","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Epidemiological Characteristics of Hemorrhagic Fever with Renal Syndrome in Longyou County, China"],"prefix":"10.3390","volume":"17","author":[{"given":"Jing","family":"Ni","sequence":"first","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, Hangzhou 310013, China"},{"name":"Department of Communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejun","family":"Kong","sequence":"additional","affiliation":[{"name":"Longyou Centre for Disease Control and Prevention, Quzhou 324400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongbing","family":"Chen","sequence":"additional","affiliation":[{"name":"Longyou Centre for Disease Control and Prevention, Quzhou 324400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiming","family":"Zeng","sequence":"additional","affiliation":[{"name":"Longyou Centre for Disease Control and Prevention, Quzhou 324400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3916-1306","authenticated-orcid":false,"given":"Bingdong","family":"Zhan","sequence":"additional","affiliation":[{"name":"Quzhou Centre for Disease Control and Prevention, Quzhou 324000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China"},{"name":"Zhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Hangzhou 310051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sehgal, A., Mehta, S., Sahay, K., Martynova, E., Rizvanov, A., Baranwal, M., Chandy, S., Khaiboullina, S., Kabwe, E., and Davidyuk, Y. 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