{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T02:02:59Z","timestamp":1779328979389,"version":"3.51.4"},"reference-count":48,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Agriculture, Food and the Marine, Equine Technical Support and Equine Breeding Schemes 2024","award":["22\/ETS\/2024"],"award-info":[{"award-number":["22\/ETS\/2024"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Equine rotavirus A (RVA) is a major cause of debilitating diarrhoea in neonatal foals globally. The aim of this study was to characterise RVA viruses currently circulating in Ireland and to identify risk factors associated with disease outbreaks. Of the 377 samples submitted during 2023 and 2024, 48 foals from 36 outbreaks were confirmed to be RVA-positive by real-time PCR. The viruses detected were genotyped by VP7 and VP4 gene sequencing. In 2024, the attending veterinary surgeon was contacted, and epidemiological data were collected. These included the vaccination status of the foal\u2019s dam and the clinician\u2019s opinion of the hygiene standard and stocking density on the farm. During the study period, 37 G3 RVAs were detected on 26 premises and 7 G14 RVAs were detected on 6 premises. Phylogenetic analysis indicated that all the viruses characterised were of the G3A subtype and the P[12]genotype and were closely related to viruses previously identified in Europe and Japan. Farm hygiene standards and stocking rates, with some exceptions, were considered satisfactory by the clinicians. However, vaccination coverage needs to be improved as the dams of the affected foals were unvaccinated on 68% of farms.<\/jats:p>","DOI":"10.3390\/v17040511","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T08:21:41Z","timestamp":1743495701000},"page":"511","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Equine Rotavirus A Outbreaks in Ireland (2023\u20132024): An Epidemiological Investigation and Virus Genotyping"],"prefix":"10.3390","volume":"17","author":[{"given":"Ann","family":"Cullinane","sequence":"first","affiliation":[{"name":"Virology Unit, The Irish Equine Centre, Johnstown, Naas, Co., W91 RH93 Kildare, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Garvey","sequence":"additional","affiliation":[{"name":"Virology Unit, The Irish Equine Centre, Johnstown, Naas, Co., W91 RH93 Kildare, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Dayot","sequence":"additional","affiliation":[{"name":"Virology Unit, The Irish Equine Centre, Johnstown, Naas, Co., W91 RH93 Kildare, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabija","family":"Lukaseviciute","sequence":"additional","affiliation":[{"name":"Virology Unit, The Irish Equine Centre, Johnstown, Naas, Co., W91 RH93 Kildare, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/258631a0","article-title":"Characterisation of a rotavirus.20b","volume":"258","author":"Newman","year":"1975","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1099\/vir.0.039255-0","article-title":"Complete molecular genome analyses of equine rotavirus A strains from different continents reveal several novel genotypes and a largely conserved genotype constellation","volume":"93","author":"Matthijnssens","year":"2012","journal-title":"J. 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