{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:05:49Z","timestamp":1760101549227,"version":"build-2065373602"},"reference-count":16,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Cytomegalovirus is an enveloped DNA virus. All forms of CMV infection\u2014primary infection, reactivation, and infection with a different strain\u2014may be asymptomatic. The risk of vertical transmission in the periconceptional period is approximately 20%, the risk of primary infection in the first trimester is approximately 30%, and in the third trimester the risk increases to 70%. However, the most severe forms of congenital cytomegaly in newborns are related to infections in the periconceptional period. Offering a vaccine to the seronegative patients planning pregnancy may decrease incidents of congenital cytomegaly in neonates. The authors performed retrospective analysis of seroprevalence of CMV in 909 women who reported for pre-conceptional visits or routine pregnancy follow-ups (2003\u20132023). In the analyzed group, 577 (63.7%) women were seropositive. No influence related to the women\u2019s age and place of residence was found. Higher seroprevalence was observed in women with children or those working in contact with many people. In the group of 332 seronegative patients, 21 (0.6%) were diagnosed with primary infection during pregnancy. Vaccinating 36.3% of patients planning pregnancy could significantly decrease the risk of primary infection during pregnancy, vertical transmission of CMV, and symptomatic infection in the neonates.<\/jats:p>","DOI":"10.3390\/v17040537","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T05:59:00Z","timestamp":1744091940000},"page":"537","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cytomegalovirus Seroprevalence in Northern Poland in the Population Planning Pregnancy and Pregnant Women"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4171-9479","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"\u015awi\u0105tkowska-Freund","sequence":"first","affiliation":[{"name":"The Academy of Applied Medical and Social Sciences, Lotnicza 2, 82-300 Elbl\u0105g, Poland"},{"name":"The Ludwik Rydygier Provincial Polyclinical Hospital in Torun, \u015aw. J\u00f3zefa 53-59, 87-100 Toru\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1309-6307","authenticated-orcid":false,"given":"Szymon","family":"Bednarek","sequence":"additional","affiliation":[{"name":"The Ludwik Rydygier Provincial Polyclinical Hospital in Torun, \u015aw. J\u00f3zefa 53-59, 87-100 Toru\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1002-814X","authenticated-orcid":false,"given":"Natalia","family":"Sasak-Cie\u015blar","sequence":"additional","affiliation":[{"name":"The Ludwik Rydygier Provincial Polyclinical Hospital in Torun, \u015aw. J\u00f3zefa 53-59, 87-100 Toru\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Koci\u0119cka","sequence":"additional","affiliation":[{"name":"Powiatowe Centrum Zdrowia w Kartuzach, Ceynowy 7, 83-300 Kartuzy, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawe\u0142","family":"Powro\u017anik","sequence":"additional","affiliation":[{"name":"Medical University of Gdansk, Marii Sk\u0142odowskiej-Curie 3a, 80-210 Gda\u0144sk, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Waldman","sequence":"additional","affiliation":[{"name":"Poznan University of Medical Sciences, Collegium Maius, Fredry 10, 61-701 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Pontes, K.F.M., Nardozza, L.M.M., and Peixoto, A.B. (2024). 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Dictionary of Cancer Terms, Available online: https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/seroprevalence."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1128\/CVI.00487-14","article-title":"Role of cytomegalovirus (CMV) IgG avidity testing in diagnosing primary CMV infection during pregnancy","volume":"21","author":"Prince","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.5604\/17331331.1227668","article-title":"High Seroprevalence of CMV Among Women of Childbearing Age Implicates High Burden of Congenital Cytomegalovirus Infection in Poland","volume":"65","author":"Siennicka","year":"2017","journal-title":"Pol. J. Microbiol."},{"key":"ref_15","first-page":"337","article-title":"Seroprevalence of cytomegalovirus infections in the population of Polish pregnant women","volume":"83","author":"Gaj","year":"2012","journal-title":"Ginekol. Pol."},{"key":"ref_16","unstructured":"(2025, April 05). Regulation of the Minister of Health of 16 August 2018 on the Organizational Standard of Perinatal Care. Dz.U. 2018. pos. 1756, Available online: https:\/\/isap.sejm.gov.pl\/isap.nsf\/DocDetails.xsp?id=WDU20180001756."}],"container-title":["Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-4915\/17\/4\/537\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:11:31Z","timestamp":1760029891000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-4915\/17\/4\/537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,7]]},"references-count":16,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["v17040537"],"URL":"https:\/\/doi.org\/10.3390\/v17040537","relation":{},"ISSN":["1999-4915"],"issn-type":[{"type":"electronic","value":"1999-4915"}],"subject":[],"published":{"date-parts":[[2025,4,7]]}}}