{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:07:17Z","timestamp":1793113637211,"version":"4.5.0"},"reference-count":31,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Blood transfusion remains vital in healthcare but poses risks, particularly from transfusion-transmissible viral infections (TTVIs). This study aims to determine the seroprevalence of HIV, HBV, and HCV among blood donors in Borgou (Benin) in 2023. This prospective, cross-sectional study involved voluntary, non-remunerated blood donors recruited via mobile campaigns and at a fixed site from January to December 2023. Screening for HIV, HBV, and HCV was performed using fourth-generation ELISA (Biorad\u00ae). Data analysis used SPSS with Chi-square test of independence (p &lt; 0.05), and multiple logistic regression identified independent risk factors. Among 9646 donors, 87.80% were male (sex ratio 7.19), mostly aged 18\u201324 (55.93%), with students forming the largest group (58.67%). Mobile units collected 70.80% of donations; 52.60% were repeat donors. Overall TTVI seroprevalence was 9.35%, with HBV (6.29%) most common, followed by HCV (1.78%) and HIV (1.28%). Chi-square tests revealed significant associations between serostatus and donor status, donation site, and occupation, but not sex. Logistic regression identified independent risk factors: age, donor status, and donation site were significantly associated with HIV infection; male sex, older age, occupation, and donor status predicted HBV infection; and only donor status was significantly associated with HCV infection. These findings highlight the need for targeted recruitment and awareness strategies to improve transfusion safety.<\/jats:p>","DOI":"10.3390\/v17081107","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T15:51:02Z","timestamp":1755013862000},"page":"1107","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Seroprevalence of Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Among Blood Donors in Borgou, Benin in 2023: A Cross-Sectional Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Kamel-Dine","family":"Djaliri","sequence":"first","affiliation":[{"name":"Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Laboratory of Applied Microbiology, Polytechnic School of Abomey-Calavi, Cotonou 01 P.O. Box 2009, Benin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brice Boris","family":"Legba","sequence":"additional","affiliation":[{"name":"Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Laboratory of Applied Microbiology, Polytechnic School of Abomey-Calavi, Cotonou 01 P.O. Box 2009, Benin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9047-7299","authenticated-orcid":false,"given":"Victorien","family":"Dougnon","sequence":"additional","affiliation":[{"name":"Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Laboratory of Applied Microbiology, Polytechnic School of Abomey-Calavi, Cotonou 01 P.O. Box 2009, Benin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelsalam","family":"Tidjani","sequence":"additional","affiliation":[{"name":"Laboratory for Research in Food Science and Nutrition, University of N\u2019Djamena, N\u2019Djamena P.O. Box 1117, Chad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8160-5954","authenticated-orcid":false,"given":"Lamine","family":"Baba-Moussa","sequence":"additional","affiliation":[{"name":"Laboratory of Biology and Molecular Typing in Microbiology, Faculty of Sciences and Technology, University of Abomey-Calavi, Cotonou 01 P.O. Box 2009, Benin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Lefr\u00e8re, J.-J., and Rouger, P. (2009). Pratique Nouvelle de la Transfusion Sanguine, Masson Elsevier. [1st ed.]. Available online: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9782294707346X00013.","DOI":"10.1016\/B978-2-294-70734-6.00010-6"},{"key":"ref_2","unstructured":"World Health Organization (2025, July 06). Blood Transfusion. 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