{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T17:43:49Z","timestamp":1775756629372,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Children with Congenital Zika Virus Syndrome (CZVS) experience severe neurological and nutritional impairments. Although immediate clinical consequences are well-documented, long-term anthropometric and nutritional outcomes remain poorly understood. This study assessed longitudinal anthropometric and nutritional outcomes in children affected by CZVS. A cohort of 38 children aged \u2265 5 years diagnosed with CZVS was followed at a reference center in Northeast Brazil. Anthropometric measures (weight, height, BMI, head circumference) were collected using standardized methods, including digital scales and anthropometric tape measures. Growth was analyzed using WHO Anthro and WHO Anthro Plus software (version 3.2.2). Dietary intake was evaluated through two 24 h recalls and analyzed with NutWIN 2.5 software. Nutritional status was classified using WHO growth standards, and associations between dietary intake and BMI were statistically examined. Children showed significant linear growth improvement (p = 0.007) without corresponding weight gain, leading to worsening BMI classifications (p = 0.017). Dietary evaluations revealed limited dietary diversity, frequent intake of ultra-processed foods, inadequate fruit consumption, and widespread insufficiencies in caloric and micronutrient intake (zinc, calcium, iron, vitamin D). Low carbohydrate intake was significantly associated with inadequate BMI (p = 0.030). Multidisciplinary nutritional interventions addressing medical, dietary, educational, and socioeconomic factors are essential for improving health outcomes in children with CZVS.<\/jats:p>","DOI":"10.3390\/v17091239","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:56:51Z","timestamp":1757923011000},"page":"1239","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long-Term Nutritional Deficits and Growth Patterns in Children with Congenital Zika Virus Syndrome: Evidence from a Brazilian Cohort"],"prefix":"10.3390","volume":"17","author":[{"given":"Carolina Santos Souza","family":"Tavares","sequence":"first","affiliation":[{"name":"Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju 49060-100, SE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel Souza","family":"Marques","sequence":"additional","affiliation":[{"name":"Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju 49060-100, SE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1401-8611","authenticated-orcid":false,"given":"Janiele de S\u00e1","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju 49060-100, SE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela Barros Barbosa","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju 49060-100, SE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique Carla da Silva","family":"Reis","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy, Alagoas State University of Health Sciences, Maceio 57010-382, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Ricardo","family":"Martins-Filho","sequence":"additional","affiliation":[{"name":"Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju 49060-100, SE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1590\/s1678-9946202062056","article-title":"Congenital Zika syndrome: Association between the gestational trimester of maternal infection, severity of brain computed tomography findings and microcephaly at birth","volume":"62","author":"Mendes","year":"2020","journal-title":"Rev. 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