{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T20:40:49Z","timestamp":1770410449343,"version":"3.49.0"},"reference-count":42,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>TORCH pathogens are often asymptomatic in healthy adults but can cause foetal death when transmitted during pregnancy; therefore, accurate regional data are essential for screening. This study aimed to determine first-trimester TORCH seropositivity and to inform the development of hospital-based and national screening algorithms. This study analysed test results from 7481 pregnant women aged 15\u201349 years who participated between January 2020 and December 2024. TORCH serological results obtained using the MAGLUMI X3\/X6 system (Snibe, Shenzhen, China) were analysed with Statistical Package for the Social Sciences. Anti-HCV positivity was 0.12% (9\/7166), anti-Toxoplasma gondii IgG positivity was 16.5% (1027\/6204), anti-rubella IgG positivity was 95.5% (5809\/6080), and anti-CMV IgG positivity was 98.69% (6130\/6211). Syphilis seropositivity among pregnant women was 0.2% (13\/4991). Significant differences by age groups (15\u201324, 25\u201334, and &gt;35 years) were observed for rubella IgG (p &lt; 0.001), T. gondii IgG (p &lt; 0.001), and HBsAg positivity (p = 0.009). This study investigated TORCH seropositivity among pregnant women in our hospital region and underscores the need for targeted public health initiatives to reduce the risk of congenital infections. It recommends systematic first-trimester assessment of TORCH exposure, standardized data recordings, the establishment of national screening programmes, and careful consideration of testing costs.<\/jats:p>","DOI":"10.3390\/v18020206","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T10:35:37Z","timestamp":1770287737000},"page":"206","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Screening of Rubella Virus, Cytomegalovirus, Hepatitis B Virus, Hepatitis C Virus, HIV, Syphilis, and Toxoplasma gondii Antibodies in Pregnant Women"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8541-7742","authenticated-orcid":false,"given":"Fatih Mehmet","family":"Ak\u0131ll\u0131","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Sincan Training and Research Hospital, Health Sciences University, Ankara 34668, Turkey"},{"name":"Department of Medical Microbiology, Aksaray Training and Research Hospital, Aksaray 68200,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8975-8368","authenticated-orcid":false,"given":"Fatih","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sincan Training and Research Hospital, Health Sciences University, Ankara 34668, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8920-1444","authenticated-orcid":false,"given":"Taylan","family":"Onat","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sincan Training and Research Hospital, Health Sciences University, Ankara 34668, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kara\u00e7or, T. 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