{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:01:45Z","timestamp":1785402105852,"version":"3.56.0"},"reference-count":52,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"https:\/\/ror.org\/00x0ma614","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/03swz6y49","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Rio Grande do Sul","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/05k49za97","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Pr\u00f3-reitoria de Pesquisa da Universidade Federal do Rio Grande do Sul"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Bovine viral diarrhea virus (BVDV) is a major cattle pathogen associated with significant economic losses worldwide. In Brazil, the high genetic diversity of circulating strains represents an additional challenge for disease control. To update the molecular epidemiology of BVDV in southern Brazil, 16,198 bovine serum samples collected in 2020 through a national surveillance program were screened for pestivirus RNA by RT-qPCR. Forty-nine samples (0.36%) were positive and subjected to partial sequencing of the 5\u2032UTR and Npro regions. Phylogenetic analysis identified BVDV-1a (25\/49; 51%), BVDV-1b (1\/49; 2%), BVDV-1d (7\/49; 14%), and BVDV-2b (16\/49; 33%), with no detection of HoBiPeV. When compared descriptively with data from 2010 in the same region, BVDV-1a remained the most frequent subgenotype, while BVDV-2b also represented a substantial proportion of detections, contrasting with other regions worldwide. Although the two datasets are not directly comparable, and no statistically significant differences were observed, these findings provide an updated overview of circulating BVDV subgenotypes in Rio Grande do Sul. The absence of HoBiPeV contrasts with reports from other regions of Brazil and suggests a distinct regional pattern of pestivirus circulation. Overall, the results reinforce the importance of continuous genomic surveillance to monitor changes in viral diversity and support control strategies in cattle populations.<\/jats:p>","DOI":"10.3390\/v18050498","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T11:40:12Z","timestamp":1777981212000},"page":"498","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genomic Surveillance of BVDV in Southern Brazil: What Changed After a Decade in Rio Grande do Sul?"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7852-8804","authenticated-orcid":false,"given":"Leticia F.","family":"Baumbach","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Virologia Veterin\u00e1ria, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8427-584X","authenticated-orcid":false,"given":"Raquel S.","family":"Alves","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Veterin\u00e1ria, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1120-2882","authenticated-orcid":false,"given":"Laura J.","family":"Camargo","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Veterin\u00e1ria, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-6079","authenticated-orcid":false,"given":"Eduardo O.","family":"Sanguinet","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Veterin\u00e1ria, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia S.","family":"Santos","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Veterin\u00e1ria, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4080-1737","authenticated-orcid":false,"given":"Lucas","family":"Marian","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Patologia Animal, Centro de Ci\u00eancias Agroveterin\u00e1rias, Universidade do Estado de Santa Catarina (UDESC), Lages 88520-000, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela E.","family":"Birlem","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunologia e Biologia Molecular, Faculdade de Veterin\u00e1ria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Federal de Defesa Agropecu\u00e1ria (LFDA\/RS), Minist\u00e9rio da Agricultura Pecu\u00e1ria e Abastecimento (MAPA), Porto Alegre 91780-580, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiano","family":"Barreto","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Federal de Defesa Agropecu\u00e1ria (LFDA\/RS), Minist\u00e9rio da Agricultura Pecu\u00e1ria e Abastecimento (MAPA), Porto Alegre 91780-580, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Marcos 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