{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:36:11Z","timestamp":1791200171860,"version":"4.2.0"},"reference-count":129,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2015,7,7]],"date-time":"2015-07-07T00:00:00Z","timestamp":1436227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"This work was partly supported by the Agence Nationale de la Recherche (ANR 11BSV3002803)."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Interferon (IFN) treatment induces the expression of hundreds of IFN-stimulated genes (ISGs). However, only a selection of their products have been demonstrated to be responsible for the inhibition of rhabdovirus replication in cultured cells; and only a few have been shown to play a role in mediating the antiviral response in vivo using gene knockout mouse models. IFNs inhibit rhabdovirus replication at different stages via the induction of a variety of ISGs. This review will discuss how individual ISG products confer resistance to rhabdoviruses by blocking viral entry, degrading single stranded viral RNA, inhibiting viral translation or preventing release of virions from the cell. Furthermore, this review will highlight how these viruses counteract the host IFN system.<\/jats:p>","DOI":"10.3390\/v7072794","type":"journal-article","created":{"date-parts":[[2015,7,8]],"date-time":"2015-07-08T10:10:02Z","timestamp":1436350202000},"page":"3675-3702","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Resistance to Rhabdoviridae Infection and Subversion of Antiviral Responses"],"prefix":"10.3390","volume":"7","author":[{"given":"Danielle","family":"Blondel","sequence":"first","affiliation":[{"name":"Institute for Integrative Biology of the Cell (I2BC), Universit\u00e9 Paris-Saclay, CEA, CNRS UMR 9198, Universit\u00e9 Paris-Sud, Gif-sur-Yvette 91190, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghizlane","family":"Maarifi","sequence":"additional","affiliation":[{"name":"INSERM UMR-S 1124, Universit\u00e9 Paris Descartes, Centre Interdisciplinaire Chimie Biologie-Paris (FR 3567, CNRS), 75270 Paris Cedex 6, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Nisole","sequence":"additional","affiliation":[{"name":"INSERM UMR-S 1124, Universit\u00e9 Paris Descartes, Centre Interdisciplinaire Chimie Biologie-Paris (FR 3567, CNRS), 75270 Paris Cedex 6, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounira","family":"Chelbi-Alix","sequence":"additional","affiliation":[{"name":"INSERM UMR-S 1124, Universit\u00e9 Paris Descartes, Centre Interdisciplinaire Chimie Biologie-Paris (FR 3567, CNRS), 75270 Paris Cedex 6, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2015,7,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.meegid.2009.02.005","article-title":"The rhabdoviruses: Biodiversity, phylogenetics, and evolution","volume":"9","author":"Kuzmin","year":"2009","journal-title":"Infect. 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