{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:01:08Z","timestamp":1790960468668,"version":"4.1.0"},"reference-count":84,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2017,8,12]],"date-time":"2017-08-12T00:00:00Z","timestamp":1502496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Viruses"],"abstract":"<jats:p>Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here, we describe how IAV infection triggers cellular apoptosis and how this process can be exploited towards the development of new therapeutics, which might be more effective than the currently available anti-influenza drugs.<\/jats:p>","DOI":"10.3390\/v9080223","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T10:23:12Z","timestamp":1502706192000},"page":"223","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":100,"title":["Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis"],"prefix":"10.3390","volume":"9","author":[{"given":"Jung","family":"Shim","sequence":"first","affiliation":[{"name":"Institut Pasteur Korea, Gyeonggi-do 13488, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhee","family":"Kim","sequence":"additional","affiliation":[{"name":"Institut Pasteur Korea, Gyeonggi-do 13488, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanel","family":"Tenson","sequence":"additional","affiliation":[{"name":"Institute of Technology, University of Tartu, Tartu 50090, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Young","family":"Min","sequence":"additional","affiliation":[{"name":"Institut Pasteur Korea, Gyeonggi-do 13488, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7716-6955","authenticated-orcid":false,"given":"Denis","family":"Kainov","sequence":"additional","affiliation":[{"name":"Institut Pasteur Korea, Gyeonggi-do 13488, Korea"},{"name":"Institute of Technology, University of Tartu, Tartu 50090, Estonia"},{"name":"Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim 7028, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,8,12]]},"reference":[{"key":"ref_1","unstructured":"(2017, July 08). 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