{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T20:55:30Z","timestamp":1774126530310,"version":"3.50.1"},"reference-count":15,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Objectives: In this communication, we wish to remember the important historical role played by Marcel Proust\u2019s father, the now mostly forgotten Achille-Adrien Proust (1834\u20131903). Study Design and Methods: His career, scientific interests and, above all, his brilliant intuitions and suggestions in the fight against cholera in the 19th century are recalled. Results and Conclusions: His role in the promotion of a globally effective vision of public hygiene and health is stressed as a bright example for modern physicians fighting contemporary epidemics.<\/jats:p>","DOI":"10.3390\/vaccines10050644","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T02:04:22Z","timestamp":1650420262000},"page":"644","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["In Search of a Lost Father: Adrien Proust (1834\u20131903), An Almost Forgotten Public Health Pioneer"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2388-5545","authenticated-orcid":false,"given":"Donatella","family":"Lippi","sequence":"first","affiliation":[{"name":"Department of Experimental and Clinical Medicine, School of Sciences of Human Health, University of Florence, 50134 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Varotto","sequence":"additional","affiliation":[{"name":"Archaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide 5001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9695-7549","authenticated-orcid":false,"given":"Sara","family":"Boccalini","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Florence, Viale GB Morgagni 48, 50134 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6013-8779","authenticated-orcid":false,"given":"Angela","family":"Bechini","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Florence, Viale GB Morgagni 48, 50134 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco Maria","family":"Galassi","sequence":"additional","affiliation":[{"name":"Archaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide 5001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,20]]},"reference":[{"key":"ref_1","first-page":"833","article-title":"Achille-Adrien Proust, M.D.: Doctor to river basins","volume":"50","author":"Straus","year":"1974","journal-title":"Bull. N. Y. Acad. Med."},{"key":"ref_2","unstructured":"Acad\u00e9mie Nationale de M\u00e9decine (1991). Index Biographique des Membres, des Associ\u00e9s et des Correspondants de l\u2019Acad\u00e9mie de M\u00e9decine: 1820\u20131990, Acad\u00e9mie Nationale de M\u00e9decine. [4th ed.]."},{"key":"ref_3","unstructured":"Elogepar, E. (1903). Lancereaux le 1er d\u00e9cembre 1903. Bulletin de l\u2019Acad\u00e9mie de M\u00e9decine, Available online: https:\/\/gallica.bnf.fr\/ark:\/12148\/bpt6k408710h.texteBrut?download=1."},{"key":"ref_4","unstructured":"Proust, A. (1862). Du Pneumothorax Essentiel ou Pneumothorax sans Perforation. [Ph.D. Thesis]. Available online: https:\/\/www.biusante.parisdescartes.fr\/sfhm\/hsm\/HSMx1968x002x003_4\/HSMx1968x002x003_4x0171.pdf."},{"key":"ref_5","unstructured":"Proust, A. (1866). Des Diff\u00e9rentes Formes de Ramollissement du Cerveau. [Thesis, Facult\u00e9 de M\u00e9decine de Paris]. Available online: https:\/\/wellcomecollection.org\/works\/pzv28rb8."},{"key":"ref_6","unstructured":"Masson, G. (2022, April 10). Essai sur L\u2019hygi\u00e8ne Internationale ses Applications Contre la Peste, la Fi\u00e8vre Jaune et le Chol\u00e9ra Asiatique (Avec une Carte Indiquant la Marche des \u00c9pid\u00e9mies de Chol\u00e9ra, par les Routes de Terre et la Voie Maritime), Available online: https:\/\/wellcomecollection.org\/works\/m3n284vw."},{"key":"ref_7","first-page":"63","article-title":"L\u2019hygi\u00e9niste adrien proust, son univers, la peste et ses id\u00e9es de politique sanitaire internationale","volume":"45","author":"Hillemand","year":"2011","journal-title":"Hist. Sci. Med."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Howard-Jones, N. (1975). The Scientific Background of the International Sanitary Conferences 1851\u20131938, WHO.","DOI":"10.1001\/jama.1976.03270050058042"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1096\/fj.15-0101ufm","article-title":"Ebola, dynamin, and the cordon sanitaire of Dr. Adrien Proust","volume":"29","author":"Weissmann","year":"2015","journal-title":"FASEB J."},{"key":"ref_10","unstructured":"(2022, March 25). Fifty-Eighth World Health Assembly. Resolution WHA58.3. Revision of the International Health Regulations. Available online: https:\/\/apps.who.int\/gb\/ebwha\/pdf_files\/WHA58\/WHA58_3-en.pdf."},{"key":"ref_11","unstructured":"WHO (2022, March 25). Statement on the Second Meeting of the International Health Regulations (2005) Emergency Committee Regarding the Outbreak of Novel Coronavirus (2019-nCoV). Available online: https:\/\/www.who.int\/news\/item\/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12992-021-00794-1","article-title":"Strengthening global health security\u2014Lessons learned from public health England\u2019s international health regulations strengthening project","volume":"18","author":"Carlson","year":"2022","journal-title":"Glob. Health"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ejim.2020.12.021","article-title":"Flying higher than politics: The goal of preventive medicine at the time of the COVID-19 pandemic","volume":"86","author":"Galassi","year":"2021","journal-title":"Eur. J. Intern. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s11739-020-02351-x","article-title":"Role of doctors in epidemics: Historical perspectives and implications for COVID-19","volume":"15","author":"Lippi","year":"2020","journal-title":"Intern. Emerg. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.puhe.2020.06.058","article-title":"Sinophobia as the disease and palaeopathology as the cure: Response to Adja et al","volume":"187","author":"Galassi","year":"2020","journal-title":"Public Health"}],"container-title":["Vaccines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/5\/644\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:57:09Z","timestamp":1760137029000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/5\/644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,20]]},"references-count":15,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["vaccines10050644"],"URL":"https:\/\/doi.org\/10.3390\/vaccines10050644","relation":{},"ISSN":["2076-393X"],"issn-type":[{"value":"2076-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,20]]}}}