{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:19:48Z","timestamp":1790662788025,"version":"4.1.0"},"reference-count":14,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009053","name":"Department of BioTechnology (DBT) Wellcome India Alliance Intermediate Career Fellowship in Clinical and Public Health","doi-asserted-by":"publisher","award":["IA\/CPHI\/18\/1\/503936"],"award-info":[{"award-number":["IA\/CPHI\/18\/1\/503936"]}],"id":[{"id":"10.13039\/501100009053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Pertussis, commonly known as whooping cough, is one of the most poorly controlled vaccine-preventable diseases in the world. South-East Asia is estimated to contribute the most to childhood disease burden while this remains largely unexplored in India. The clinical diagnosis of pertussis in young children is a challenge as the classical four-stage presentation with paroxysmal cough or whoop may be absent. It is also difficult to differentiate from other respiratory infections which can cause pertussis-like illness. Children below two years with prolonged cough illness attending an urban pediatric center in western India, were evaluated for pertussis and viral infections by molecular methods. Bordetella pertussis and B. holmesii were confirmed in three each of 45 suspected cases, and RSV-A and hMPV were the most common viruses that were detected. These organisms can mimic mild cases of pertussis and need to be considered in differential diagnosis of prolonged cough illness in young children. The accurate etiology of prolonged cough illness needs to be detected and documented to ensure appropriate management and accurate estimates of disease burden.<\/jats:p>","DOI":"10.3390\/vaccines10081191","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T01:41:16Z","timestamp":1659058876000},"page":"1191","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Looking beyond Pertussis in Prolonged Cough Illness of Young Children"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1517-0454","authenticated-orcid":false,"given":"Rajlakshmi","family":"Viswanathan","sequence":"first","affiliation":[{"name":"Bacteriology Group, ICMR-National Institute of Virology, 130\/1, Sus Road, Pashan, Pune 411021, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Bafna","sequence":"additional","affiliation":[{"name":"Department of Pediatric Medicine, Jehangir Hospital, 32, Sassoon Road, Pune 411001, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9968-8957","authenticated-orcid":false,"given":"Manohar Lal","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Influenza Group, ICMR-National Institute of Virology, 20-A, Ambedkar Road, Pune 411001, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Pediatric Medicine, Jehangir Hospital, 32, Sassoon Road, Pune 411001, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savita","family":"Katendra","sequence":"additional","affiliation":[{"name":"Bacteriology Group, ICMR-National Institute of Virology, 130\/1, Sus Road, Pashan, Pune 411021, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shradha","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Bacteriology Group, ICMR-National Institute of Virology, 130\/1, Sus Road, Pashan, Pune 411021, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheetal","family":"Jadhav","sequence":"additional","affiliation":[{"name":"Influenza Group, ICMR-National Institute of Virology, 20-A, Ambedkar Road, Pune 411001, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0140-6736(14)61698-6","article-title":"Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: An updated systematic analysis","volume":"385","author":"Liu","year":"2015","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1099\/jmm.0.47847-0","article-title":"Pertussis in India","volume":"58","author":"Dahiya","year":"2009","journal-title":"J. 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PLoS Pathog., 9.","DOI":"10.1371\/journal.ppat.1003418"}],"container-title":["Vaccines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/8\/1191\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:57:20Z","timestamp":1760140640000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/8\/1191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,27]]},"references-count":14,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,8]]}},"alternative-id":["vaccines10081191"],"URL":"https:\/\/doi.org\/10.3390\/vaccines10081191","relation":{},"ISSN":["2076-393X"],"issn-type":[{"value":"2076-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,27]]}}}