{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T17:59:37Z","timestamp":1785002377071,"version":"3.55.0"},"reference-count":36,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>People with pre-exposure prophylaxis (PrEP) or living with HIV are a high-risk population for monkeypox virus (MPXV) infection. It is important to achieve high MPXV vaccination coverage rates in this group. This project used self-reporting to assess vaccine hesitancy for the smallpox vaccine and acceptance among men having sex with men with PrEP or living with HIV. In total, 52 (33.6%) participants among the 155 declared their hesitancy to be vaccinated against MPXV. Moreover, 20.7% patients with PrEP declared a hesitant attitude towards the smallpox vaccine compared to 40.2% of the HIV patients, p = 0.013. This difference remained not significant after adjustment for age (p = 0.119) and after adjustment for both age and number of different sexual partners (p = 0.406). Among PrEP people, those who expressed concerns about people getting more vaccines than needed (p = 0.012) were less likely to accept vaccination, whereas an increased number of different sexual partners during the previous month was significantly associated with acceptance of vaccination (p = 0.034). Among HIV people, those who expressed concerns about being infected by MPXV (p &lt; 0.001), those who expressed that the smallpox vaccine should be compulsory for people at risk (p &lt; 0.001) and those with an increased the number of different sexual partners the previous month (p = 0.018) were significantly associated with higher acceptance of MPXV vaccination. Our results suggest that vaccine strategy would be efficient in France with a communication strategy emphasizing the benefits of vaccination and the potential MPXV risk infection for health in PrEP and HIV people. Other preventive actions should be implemented, including reduction in sexual partners.<\/jats:p>","DOI":"10.3390\/vaccines10101629","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T01:23:16Z","timestamp":1664414596000},"page":"1629","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Monkeypox Vaccine Hesitancy in French Men Having Sex with Men with PrEP or Living with HIV in France"],"prefix":"10.3390","volume":"10","author":[{"given":"David","family":"Zucman","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, R\u00e9seau Ville H\u00f4pital Val de Seine, Foch Hospital, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwan","family":"Fourn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, R\u00e9seau Ville H\u00f4pital Val de Seine, Foch Hospital, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Touche","sequence":"additional","affiliation":[{"name":"Department Epidemiology-Data-Biostatistics, Delegation of Clinical Research and Innovation (DRCI), Foch Hospital, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Majerholc","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, R\u00e9seau Ville H\u00f4pital Val de Seine, Foch Hospital, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Vall\u00e9e","sequence":"additional","affiliation":[{"name":"Department Epidemiology-Data-Biostatistics, Delegation of Clinical Research and Innovation (DRCI), Foch Hospital, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"o1239","DOI":"10.1136\/bmj.o1239","article-title":"Seven Monkeypox Cases Are Confirmed in England","volume":"377","author":"Mahase","year":"2022","journal-title":"BMJ"},{"key":"ref_2","unstructured":"(2022, September 17). WHO Director-General\u2019s Statement at the Press Conference Following IHR Emergency Committee Regarding the Multi-Country Outbreak of Monkeypox\u201423 July 2022. Available online: https:\/\/www.who.int\/director-general\/speeches\/detail\/who-director-general-s-statement-on-the-press-conference-following-IHR-emergency-committee-regarding-the-multi--country-outbreak-of-monkeypox--23-july-2022."},{"key":"ref_3","unstructured":"(2022, September 17). Cas de Variole du Singe: Point de Situation au 15 Septembre 2022. Available online: https:\/\/www.santepubliquefrance.fr\/les-actualites\/2022\/cas-de-variole-du-singe-point-de-situation-au-15-septembre-2022."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/QAD.0000000000001715","article-title":"Acute Hepatitis A Breakthrough in MSM in Paris Area: Implementation of Targeted Hepatitis A Virus Vaccine in a Context of Vaccine Shortage","volume":"32","author":"Farfour","year":"2018","journal-title":"AIDS Lond. Engl."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"102394","DOI":"10.1016\/j.tmaid.2022.102394","article-title":"Monkeypox Virus: A Novel Sexually Transmitted Disease? A Case Report from France","volume":"49","author":"Farfour","year":"2022","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_6","unstructured":"(2022, August 17). Multi-Country Monkeypox Outbreak: Situation Update. Available online: https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON396."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2217\/17460913.2.1.17","article-title":"Human Monkeypox: An Emerging Zoonotic Disease","volume":"2","author":"Parker","year":"2007","journal-title":"Future Microbiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2200411","DOI":"10.2807\/1560-7917.ES.2022.27.22.2200411","article-title":"Monkeypox Infection Presenting as Genital Rash, Australia, May 2022","volume":"27","author":"Hammerschlag","year":"2022","journal-title":"Eurosurveillance"},{"key":"ref_9","first-page":"2200424","article-title":"Ongoing Monkeypox Virus Outbreak, Portugal, 29 April to 23 May 2022","volume":"27","author":"Ribeiro","year":"2022","journal-title":"Euro Surveill. Bull. Eur. Sur Mal. Transm. Eur. Commun. Dis. Bull."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1056\/NEJMoa2207323","article-title":"Monkeypox Virus Infection in Humans across 16 Countries\u2014April-June 2022","volume":"387","author":"Thornhill","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0140-6736(22)01436-2","article-title":"Clinical Presentation and Virological Assessment of Confirmed Human Monkeypox Virus Cases in Spain: A Prospective Observational Cohort Study","volume":"400","author":"Alemany","year":"2022","journal-title":"Lancet"},{"key":"ref_12","first-page":"2200422","article-title":"Community Transmission of Monkeypox in the United Kingdom, April to May 2022","volume":"27","author":"Vivancos","year":"2022","journal-title":"Euro Surveill. Bull. Eur. Sur Mal. Transm. Eur. Commun. Dis. Bull."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Lai, C.-C., Hsu, C.-K., Yen, M.-Y., Lee, P.-I., Ko, W.-C., and Hsueh, P.-R. (2022). Monkeypox: An Emerging Global Threat during the COVID-19 Pandemic. J. Microbiol. Immunol. Infect. Wei Mian Yu Gan Ran Za Zhi.","DOI":"10.1016\/j.jmii.2022.07.004"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Bragazzi, N.L., Kong, J.D., Mahroum, N., Tsigalou, C., Khamisy-Farah, R., Converti, M., and Wu, J. (2022). Epidemiological Trends and Clinical Features of the Ongoing Monkeypox Epidemic: A Preliminary Pooled Data Analysis and Literature Review. J. Med. Virol.","DOI":"10.1002\/jmv.27931"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s40265-022-01742-y","article-title":"Prevention and Treatment of Monkeypox","volume":"82","author":"Rizk","year":"2022","journal-title":"Drugs"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.3201\/eid2805.220292","article-title":"Imported Monkeypox from International Traveler, Maryland, USA, 2021","volume":"28","author":"Costello","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"509","DOI":"10.15585\/mmwr.mm7114a1","article-title":"Monkeypox in a Traveler Returning from Nigeria\u2014Dallas, Texas, July 2021","volume":"71","author":"Rao","year":"2022","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"4165","DOI":"10.1016\/j.vaccine.2015.04.037","article-title":"Measuring Vaccine Hesitancy: The Development of a Survey Tool","volume":"33","author":"Larson","year":"2015","journal-title":"Vaccine"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/pubmed\/fdaa230","article-title":"COVID-19 Vaccine Hesitancy among Medical Students","volume":"43","author":"Lucia","year":"2020","journal-title":"J. Public Health"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Vall\u00e9e, A., Fourn, E., Majerholc, C., Touche, P., and Zucman, D. (2021). COVID-19 Vaccine Hesitancy among French People Living with HIV. Vaccines, 9.","DOI":"10.3390\/vaccines9040302"},{"key":"ref_21","unstructured":"(2022, July 24). WHO Report of the SAGE Working Group on Vaccine Hesitancy. Available online: Https:\/\/Www.Who.Int\/Immunization\/Sage\/Meetings\/2014\/October\/SAGE_working_group_revised_report_vaccine_hesitancy.Pdf."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.15585\/mmwr.mm7136a1","article-title":"HIV and Sexually Transmitted Infections Among Persons with Monkeypox\u2014Eight U.S. Jurisdictions, May 17\u2013July 22, 2022","volume":"71","author":"Curran","year":"2022","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jinf.2022.05.028","article-title":"Transmission of Monkeypox Virus through Sexual Contact\u2014A Novel Route of Infection","volume":"85","author":"Heskin","year":"2022","journal-title":"J. Infect."},{"key":"ref_24","first-page":"2200448","article-title":"Estimated Incubation Period for Monkeypox Cases Confirmed in the Netherlands, May 2022","volume":"27","author":"Miura","year":"2022","journal-title":"Euro Surveill. Bull. Eur. Sur Mal. Transm. Eur. Commun. Dis. Bull."},{"key":"ref_25","unstructured":"(2022, August 17). Vaccines and Immunization for Monkeypox: Interim Guidance, 14 June 2022. Available online: https:\/\/www.who.int\/publications-detail-redirect\/who-mpx-immunization-2022.1."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/S0140-6736(22)00425-1","article-title":"Advancing Accurate Metrics for Future Pandemic Preparedness","volume":"399","author":"Ntoumi","year":"2022","journal-title":"Lancet"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S1473-3099(22)00354-1","article-title":"Monkeypox Outbreaks Outside Endemic Regions: Scientific and Social Priorities","volume":"22","author":"Zumla","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"5077","DOI":"10.1016\/j.vaccine.2020.04.062","article-title":"Human Monkeypox\u2014After 40 Years, an Unintended Consequence of Smallpox Eradication","volume":"38","author":"Simpson","year":"2020","journal-title":"Vaccine"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"102383","DOI":"10.1016\/j.tmaid.2022.102383","article-title":"Sexually or Intimately Transmitted Infections: A Look at the Current Outbreak of Monkeypox in 2022","volume":"49","author":"Zambrano","year":"2022","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_30","first-page":"149","article-title":"Increasing Vaccination: Putting Psychological Science Into Action","volume":"18","author":"Brewer","year":"2017","journal-title":"Psychol. Sci. Public Interest J. Am. Psychol. Soc."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"102426","DOI":"10.1016\/j.tmaid.2022.102426","article-title":"Monkeypox Caused Less Worry than COVID-19 among the General Population during the First Month of the WHO Monkeypox Alert: Experience from Saudi Arabia","volume":"49","author":"Temsah","year":"2022","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"102364","DOI":"10.1016\/j.tmaid.2022.102364","article-title":"International Outbreaks of Monkeypox Virus Infection with No Established Travel: A Public Health Concern with Significant Knowledge Gap","volume":"49","author":"Barry","year":"2022","journal-title":"Travel Med. Infect. Dis."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Alsanafi, M., Al-Mahzoum, K., and Sallam, M. (2022). Monkeypox Knowledge and Confidence in Diagnosis and Management with Evaluation of Emerging Virus Infection Conspiracies among Health Professionals in Kuwait. Pathogens, 11.","DOI":"10.3390\/pathogens11090994"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Ricc\u00f2, M., Ferraro, P., Camisa, V., Satta, E., Zaniboni, A., Ranzieri, S., Baldassarre, A., Zaffina, S., and Marchesi, F. (2022). When a Neglected Tropical Disease Goes Global: Knowledge, Attitudes and Practices of Italian Physicians towards Monkeypox, Preliminary Results. Trop. Med. Infect. Dis., 7.","DOI":"10.3390\/tropicalmed7070135"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Sallam, M., Al-Mahzoum, K., Al-Tammemi, A.B., Alkurtas, M., Mirzaei, F., Kareem, N., Al-Naimat, H., Jardaneh, L., Al-Majali, L., and AlHadidi, A. (2022). Assessing Healthcare Workers\u2019 Knowledge and Their Confidence in the Diagnosis and Management of Human Monkeypox: A Cross-Sectional Study in a Middle Eastern Country. Healthcare, 10.","DOI":"10.3390\/healthcare10091722"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1093\/ije\/17.3.643","article-title":"The Transmission Potential of Monkeypox Virus in Human Populations","volume":"17","author":"Fine","year":"1988","journal-title":"Int. J. Epidemiol."}],"container-title":["Vaccines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/10\/1629\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:41:10Z","timestamp":1760143270000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-393X\/10\/10\/1629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":36,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["vaccines10101629"],"URL":"https:\/\/doi.org\/10.3390\/vaccines10101629","relation":{},"ISSN":["2076-393X"],"issn-type":[{"value":"2076-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]}}}