{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:59:34Z","timestamp":1790643574751,"version":"4.1.0"},"reference-count":100,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"CONADI-UCC","award":["INV2623"],"award-info":[{"award-number":["INV2623"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Equine influenza is a highly contagious disease caused by the H3N8 equine influenza virus (EIV), which is endemically distributed throughout the world. It infects equids, and interspecies transmission to dogs has been reported. The H3N8 Florida lineage, which is divided into clades 1 and 2, is the most representative lineage in the Americas. The EIV infects the respiratory system, affecting the ciliated epithelial cells and preventing the elimination of foreign bodies and substances. Certain factors related to the disease, such as an outdated vaccination plan, age, training, and close contact with other animals, favor the presentation of equine influenza. This review focuses on the molecular, pathophysiological, and epidemiological characteristics of EIV in the Americas to present updated information to achieve prevention and control of the virus. We also discuss the need for monitoring the disease, the use of vaccines, and the appropriate application of those biologicals, among other biosecurity measures that are important for the control of the virus.<\/jats:p>","DOI":"10.3390\/vaccines10101718","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T05:08:02Z","timestamp":1665983282000},"page":"1718","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Equine Influenza Virus: An Old Known Enemy in the Americas"],"prefix":"10.3390","volume":"10","author":[{"given":"Juliana","family":"Gonzalez-Obando","sequence":"first","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Ciencias Animales\u2014GRICA, Facultad de Medicina Veterinaria y Zootecnia, Universidad Cooperativa de Colombia, Bucaramanga 680002, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Eduardo","family":"Forero","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Microbiolog\u00eda Veterinaria, Escuela de Microbiolog\u00eda, Universidad de Antioquia, Medell\u00edn 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5527-3995","authenticated-orcid":false,"given":"Ang\u00e9lica M","family":"Zuluaga-Cabrera","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Circular 73 N\u00b035-04, Medell\u00edn 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1447-1458","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Ruiz-Saenz","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Ciencias Animales\u2014GRICA, Facultad de Medicina Veterinaria y Zootecnia, Universidad Cooperativa de Colombia, Bucaramanga 680002, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.3389\/fmicb.2018.01941","article-title":"A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies","volume":"9","author":"Singh","year":"2018","journal-title":"Front. 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