{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:43:17Z","timestamp":1760233397464,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Science, Research and Innovation Fund","award":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"],"award-info":[{"award-number":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"]}]},{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand (NRCT) and Naresuan University","doi-asserted-by":"publisher","award":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"],"award-info":[{"award-number":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"]}],"id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Thailand Science Research and Innovation Fund Chulalongkorn University","award":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"],"award-info":[{"award-number":["R2566B001","N42A650331","CU_FRB65_hea (19)_026_30_07"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Vaccination against the SARS-CoV-2 virus (COVID-19) has proven to be the most effective measure to prevent the spread and reduce infection severity. A case report of de novo membranous nephropathy (MN) following immunization with inactivated virus vaccine (CoronaVac\u00ae, Sinovac Biotech) is presented here. A 53-year-old man presented with a sudden onset of leg edema a week after receiving an inactivated virus vaccine and a relapse of nephrotic syndrome (NS) with acute kidney injury (AKI) after a booster dose. Screening for serum anti-phospholipase A2 receptor antibody and secondary causes of MN were negative. Kidney biopsy revealed an early MN pattern with focal spike formation, whilst numerous subepithelial electron-dense deposits and a few small deposits in the mesangial area were observed through electron microscopy. A short course of steroids and oral cyclophosphamide was prescribed, resulting in the complete remission of NS and AKI. MN following SARS-CoV-2 vaccination should call for medical importance. Awareness of the association between vaccination and MN should be kept in mind to avoid unnecessary treatment with long-term immunosuppressive agents.<\/jats:p>","DOI":"10.3390\/vaccines11010080","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T03:31:17Z","timestamp":1672371077000},"page":"80","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Membranous Nephropathy following Full-Dose of Inactivated SARS-CoV-2 Virus Vaccination: A Case Report and Literature Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5134-7106","authenticated-orcid":false,"given":"Theerachai","family":"Thammathiwat","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laor","family":"Chompuk","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1238-1536","authenticated-orcid":false,"given":"Suchin","family":"Worawichawong","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijitr","family":"Boonpucknavig","sequence":"additional","affiliation":[{"name":"NHealth Company, Bangkok Hospital Group, Bangkok 10310, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supinda","family":"Sirilak","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2415-9468","authenticated-orcid":false,"given":"Sutatip","family":"Pongcharoen","sequence":"additional","affiliation":[{"name":"Division of Immunology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Watchara","family":"Pichitsiri","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talerngsak","family":"Kanjanabuch","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"},{"name":"Center of Excellence in Kidney Metabolic Disorders, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41541-021-00292-w","article-title":"SARS-CoV-2 vaccines strategies: A comprehensive review of phase 3 candidates","volume":"6","author":"Kyriakidis","year":"2021","journal-title":"NPJ Vaccines"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Cheng, H., Peng, Z., Luo, W., Si, S., Mo, M., Zhou, H., Xin, X., Liu, H., and Yu, Y. 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